JP2010522624A - 治療剤の放出のための生体侵食性層を有する医療装置 - Google Patents

治療剤の放出のための生体侵食性層を有する医療装置 Download PDF

Info

Publication number
JP2010522624A
JP2010522624A JP2010501217A JP2010501217A JP2010522624A JP 2010522624 A JP2010522624 A JP 2010522624A JP 2010501217 A JP2010501217 A JP 2010501217A JP 2010501217 A JP2010501217 A JP 2010501217A JP 2010522624 A JP2010522624 A JP 2010522624A
Authority
JP
Japan
Prior art keywords
polymer
medical device
layer
component
bioerodible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010501217A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010522624A5 (enExample
Inventor
コートニー サイクス
マーク ステッケル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Scimed Inc
Original Assignee
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scimed Life Systems Inc filed Critical Scimed Life Systems Inc
Publication of JP2010522624A publication Critical patent/JP2010522624A/ja
Publication of JP2010522624A5 publication Critical patent/JP2010522624A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
JP2010501217A 2007-03-28 2008-03-27 治療剤の放出のための生体侵食性層を有する医療装置 Pending JP2010522624A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92039407P 2007-03-28 2007-03-28
PCT/US2008/058407 WO2008121702A2 (en) 2007-03-28 2008-03-27 Medical devices having bioerodable layers for the release of therapeutic agents

Publications (2)

Publication Number Publication Date
JP2010522624A true JP2010522624A (ja) 2010-07-08
JP2010522624A5 JP2010522624A5 (enExample) 2011-05-19

Family

ID=39808861

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010501217A Pending JP2010522624A (ja) 2007-03-28 2008-03-27 治療剤の放出のための生体侵食性層を有する医療装置

Country Status (4)

Country Link
US (1) US20090074838A1 (enExample)
EP (1) EP2134380A2 (enExample)
JP (1) JP2010522624A (enExample)
WO (1) WO2008121702A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016523145A (ja) * 2013-06-21 2016-08-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 撓みコネクタを備えたステント

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8057876B2 (en) * 2008-02-25 2011-11-15 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with layers having different degradation rates
US8653155B2 (en) * 2009-08-13 2014-02-18 Boston Scientific Scimed, Inc. Polymers having lipophilic hydrocarbon and biodegradable polymeric segments
US8685433B2 (en) * 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
CN104587534A (zh) * 2013-10-31 2015-05-06 先健科技(深圳)有限公司 可吸收铁基合金支架
CN103933620B (zh) * 2014-04-09 2015-09-16 北京颐合恒瑞医疗科技有限公司 一种可吸收皮肤缝合钉及制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056312A1 (en) * 1997-06-13 1998-12-17 Scimed Life Systems, Inc. Stents having multiple layers of biodegradable polymeric composition
JP2000507218A (ja) * 1996-03-05 2000-06-13 ゲープフェリッヒ アヒム 薬剤物質を段階放出するインプラント
WO2005086831A2 (en) * 2004-03-10 2005-09-22 Orbus Medical Technologies, Inc. Endothelial ligand binding coated medical device
JP2005538809A (ja) * 2002-09-18 2005-12-22 メドトロニック ヴァスキュラー インコーポレイテッド 医療装置のための制御可能な薬剤放出勾配コーティング
WO2006027994A1 (ja) * 2004-09-08 2006-03-16 Kaneka Corporation 生体留置用ステント
WO2006074391A2 (en) * 2005-01-05 2006-07-13 Surmodics, Inc. Biodegradable coating compositions comprising blends

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5464450A (en) * 1991-10-04 1995-11-07 Scimed Lifesystems Inc. Biodegradable drug delivery vascular stent
US6663881B2 (en) * 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5824048A (en) * 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US6368658B1 (en) * 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6258121B1 (en) * 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6338739B1 (en) * 1999-12-22 2002-01-15 Ethicon, Inc. Biodegradable stent
US6545097B2 (en) * 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US20040220660A1 (en) * 2001-02-05 2004-11-04 Shanley John F. Bioresorbable stent with beneficial agent reservoirs
US20030050687A1 (en) * 2001-07-03 2003-03-13 Schwade Nathan D. Biocompatible stents and method of deployment
WO2003099169A1 (en) * 2002-05-20 2003-12-04 Orbus Medical Technologies Inc. Drug eluting implantable medical device
KR20060028695A (ko) * 2003-06-16 2006-03-31 난양 테크놀러지컬 유니버시티 고분자 스텐트 및 이의 제조 방법
WO2006002365A2 (en) * 2004-06-24 2006-01-05 Angiotech International Ag Microparticles with high loadings of a bioactive agent
KR100705210B1 (ko) * 2004-09-23 2007-04-06 주식회사 한독약품 경구투여를 위한 당뇨병 치료용 약제학적 복합제제
US20060147491A1 (en) * 2005-01-05 2006-07-06 Dewitt David M Biodegradable coating compositions including multiple layers
US8075906B2 (en) * 2005-02-01 2011-12-13 Boston Scientific Scimed, Inc. Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species
PT1883665T (pt) * 2005-04-22 2017-11-14 Univ Geneve Composições polilactídeo e usos das mesmas
US8778375B2 (en) * 2005-04-29 2014-07-15 Advanced Cardiovascular Systems, Inc. Amorphous poly(D,L-lactide) coating
US9248219B2 (en) * 2007-09-14 2016-02-02 Boston Scientific Scimed, Inc. Medical devices having bioerodable layers for the release of therapeutic agents

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507218A (ja) * 1996-03-05 2000-06-13 ゲープフェリッヒ アヒム 薬剤物質を段階放出するインプラント
WO1998056312A1 (en) * 1997-06-13 1998-12-17 Scimed Life Systems, Inc. Stents having multiple layers of biodegradable polymeric composition
JP2005538809A (ja) * 2002-09-18 2005-12-22 メドトロニック ヴァスキュラー インコーポレイテッド 医療装置のための制御可能な薬剤放出勾配コーティング
WO2005086831A2 (en) * 2004-03-10 2005-09-22 Orbus Medical Technologies, Inc. Endothelial ligand binding coated medical device
WO2006027994A1 (ja) * 2004-09-08 2006-03-16 Kaneka Corporation 生体留置用ステント
WO2006074391A2 (en) * 2005-01-05 2006-07-13 Surmodics, Inc. Biodegradable coating compositions comprising blends

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016523145A (ja) * 2013-06-21 2016-08-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 撓みコネクタを備えたステント

Also Published As

Publication number Publication date
WO2008121702A3 (en) 2009-11-05
EP2134380A2 (en) 2009-12-23
WO2008121702A2 (en) 2008-10-09
US20090074838A1 (en) 2009-03-19

Similar Documents

Publication Publication Date Title
US9248219B2 (en) Medical devices having bioerodable layers for the release of therapeutic agents
US8900619B2 (en) Medical devices for the release of therapeutic agents
US7919137B2 (en) Medical devices having adherent polymeric layers with depth-dependent properties
JP5340913B2 (ja) 生分解性ポリマー領域を有する医療デバイス
EP1838362B1 (en) Use of supercritical fluids to incorporate biologically active agents into nanoporous medical articles
JP5134013B2 (ja) スチレンイソブチレン共重合体に基づくポリマー領域を有する医療デバイス
US8586072B2 (en) Medical devices having coatings for controlled therapeutic agent delivery
US20050220853A1 (en) Controlled delivery of therapeutic agents from medical articles
KR102410365B1 (ko) 기능성 내피 세포 층의 복구를 가능하게 하는 약물 용출 스텐트 및 이의 사용 방법
EP2205292B1 (en) Therapeutic agent-eluting medical devices having textured polymeric surfaces
US8722074B2 (en) Medical devices containing radiation resistant polymers
JP2010522624A (ja) 治療剤の放出のための生体侵食性層を有する医療装置
US7767220B2 (en) Implantable or insertable medical articles having covalently modified, biocompatible surfaces
KR20230150790A (ko) 약물 용출 스텐트

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110325

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110325

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130415

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130716

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131105