JP5340913B2 - 生分解性ポリマー領域を有する医療デバイス - Google Patents
生分解性ポリマー領域を有する医療デバイス Download PDFInfo
- Publication number
- JP5340913B2 JP5340913B2 JP2009501433A JP2009501433A JP5340913B2 JP 5340913 B2 JP5340913 B2 JP 5340913B2 JP 2009501433 A JP2009501433 A JP 2009501433A JP 2009501433 A JP2009501433 A JP 2009501433A JP 5340913 B2 JP5340913 B2 JP 5340913B2
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- biodegradable polymer
- implantable
- biodegradable
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Description
〔詳細な記載〕
Claims (13)
- 生分解性ポリマー領域を有する植え込み可能または挿入可能な結晶性フラグメントを含まない医療デバイスであって、前記生分解性ポリマー領域が、(a)1000から2000ダルトンの範囲の数平均分子量(Mn)を有するポリ(エチレングリコール)ブロックを含む37°Cを下回るガラス転移温度を示す非結晶性ポリマーブロック、および(b)ポリ(d,lラクチド)ブロックを含む37°Cを超えるガラス転移温度を示す非結晶性生分解性ポリマーブロック、を有する生分解性ブロックコポリマーを含む、植え込み可能または挿入可能な医療デバイス。
- 前記医療デバイスが、ステント、ステントグラフト、血管グラフト、ガイドワイヤ、バルーン、大静脈フィルタ、大脳動脈瑠フィラーコイル、心筋プラグ、心臓弁、血管弁および組織工学スカフォルドから選択される、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ブロックコポリマーが、37°Cを下回るガラス転移温度を示す複数の前記非結晶性ポリマーブロックを含む、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ブロックコポリマーが、37°Cを超えるガラス転移温度を示す複数の前記非結晶性生分解性ポリマーブロックを含む、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ブロックコポリマーが、(a)37°Cを下回るガラス転移温度を示す単一の非結晶性ポリマーブロック、および(b)37°Cを超えるガラス転移温度を示す2つの非結晶性生分解性ポリマーブロック、を含むトリブロックコポリマーである、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 複数の前記生分解性ポリマー領域を有する、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域が、繊維の形態である、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域が、医療デバイス基板の上に配置される生分解性ポリマー層の形態である、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域の下、またはその中に配置された治療剤をさらに有する、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域が、生分解性ポリマー層の形態であり、前記ポリマー層が、治療剤を有する領域の上に配置される、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域が、生分解性ポリマー層の形態であり、前記ポリマー層が治療剤を有する、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域が、溶剤および前記生分解性ブロックコポリマーを含む溶液からの溶剤の蒸発または分散によって形成される、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
- 前記生分解性ポリマー領域が、前記生分解性ブロックコポリマーを含む溶融物を冷却することによって形成される、請求項1に記載の植え込み可能または挿入可能な医療デバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/386,273 | 2006-03-22 | ||
US11/386,273 US20070224234A1 (en) | 2006-03-22 | 2006-03-22 | Medical devices having biodegradable polymeric regions |
PCT/US2007/005654 WO2007111808A2 (en) | 2006-03-22 | 2007-03-05 | Medical devices having biodegradable polymeric regions |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009530023A JP2009530023A (ja) | 2009-08-27 |
JP5340913B2 true JP5340913B2 (ja) | 2013-11-13 |
Family
ID=38456558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009501433A Expired - Fee Related JP5340913B2 (ja) | 2006-03-22 | 2007-03-05 | 生分解性ポリマー領域を有する医療デバイス |
Country Status (6)
Country | Link |
---|---|
US (1) | US20070224234A1 (ja) |
EP (1) | EP2007447B1 (ja) |
JP (1) | JP5340913B2 (ja) |
AT (1) | ATE535267T1 (ja) |
CA (1) | CA2646751A1 (ja) |
WO (1) | WO2007111808A2 (ja) |
Families Citing this family (47)
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EP1545705A4 (en) | 2000-11-16 | 2010-04-28 | Microspherix Llc | FLEXIBLE AND / OR ELASTIC BRACHYTHERAPY SEED OR STRAND |
US6761680B2 (en) * | 2001-11-02 | 2004-07-13 | Richard A. Terwilliger | Delivery system and method for interstitial radiation therapy using seed strands constructed with preformed strand housing |
US7060020B2 (en) | 2001-11-02 | 2006-06-13 | Ideamatrix, Inc. | Delivery system and method for interstitial radiation therapy |
US7074291B2 (en) | 2001-11-02 | 2006-07-11 | Worldwide Medical Technologies, L.L.C. | Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings |
US6997862B2 (en) | 2003-05-13 | 2006-02-14 | Ideamatrix, Inc. | Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing |
GB0329654D0 (en) | 2003-12-23 | 2004-01-28 | Smith & Nephew | Tunable segmented polyacetal |
US7785291B2 (en) | 2005-03-01 | 2010-08-31 | Tulip Medical Ltd. | Bioerodible self-deployable intragastric implants |
US7699863B2 (en) * | 2005-03-01 | 2010-04-20 | Tulip Medical Ltd. | Bioerodible self-deployable intragastric implants |
US7736293B2 (en) | 2005-07-22 | 2010-06-15 | Biocompatibles Uk Limited | Implants for use in brachytherapy and other radiation therapy that resist migration and rotation |
US8187159B2 (en) | 2005-07-22 | 2012-05-29 | Biocompatibles, UK | Therapeutic member including a rail used in brachytherapy and other radiation therapy |
US7988611B2 (en) * | 2006-05-09 | 2011-08-02 | Biocompatibles Uk Limited | After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy |
CN101500623B (zh) | 2006-06-15 | 2016-08-24 | 微温森公司 | 一种由可膨胀聚合物构成的栓塞器械 |
US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
US7878964B1 (en) | 2006-09-07 | 2011-02-01 | Biocompatibles Uk Limited | Echogenic spacers and strands |
US7874976B1 (en) | 2006-09-07 | 2011-01-25 | Biocompatibles Uk Limited | Echogenic strands and spacers therein |
ES2393639T3 (es) | 2007-01-21 | 2012-12-26 | Hemoteq Ag | Producto médico para tratar cierres de conductos corporales y prevención de nuevos cierres |
WO2008129245A1 (en) | 2007-04-18 | 2008-10-30 | Smith & Nephew Plc | Expansion moulding of shape memory polymers |
EP2142227B1 (en) | 2007-04-19 | 2012-02-29 | Smith & Nephew, Inc. | Multi-modal shape memory polymers |
DE602008006181D1 (de) | 2007-04-19 | 2011-05-26 | Smith & Nephew Inc | Graft-fixierung |
US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
US7956100B2 (en) * | 2007-09-28 | 2011-06-07 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from block copolymers |
CA2709379C (en) | 2007-12-21 | 2016-08-16 | Microvention, Inc. | Hydrogel filaments for biomedical uses |
US20100042202A1 (en) * | 2008-08-13 | 2010-02-18 | Kamal Ramzipoor | Composite stent having multi-axial flexibility |
US20100030313A1 (en) * | 2008-07-31 | 2010-02-04 | Boston Scientific Scimed, Inc. | Medical articles comprising biodegradable block copolymers |
US10369256B2 (en) | 2009-07-10 | 2019-08-06 | Boston Scientific Scimed, Inc. | Use of nanocrystals for drug delivery from a balloon |
JP5933434B2 (ja) | 2009-07-17 | 2016-06-08 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 薬剤送達バルーンの製造方法 |
US8653155B2 (en) * | 2009-08-13 | 2014-02-18 | Boston Scientific Scimed, Inc. | Polymers having lipophilic hydrocarbon and biodegradable polymeric segments |
CA2777171C (en) | 2009-10-26 | 2017-09-19 | Microvention, Inc. | Embolization device constructed from expansile polymer |
EP2611476B1 (en) | 2010-09-02 | 2016-08-10 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
WO2012145431A2 (en) | 2011-04-18 | 2012-10-26 | Microvention, Inc. | Embolic devices |
WO2013022458A1 (en) | 2011-08-05 | 2013-02-14 | Boston Scientific Scimed, Inc. | Methods of converting amorphous drug substance into crystalline form |
WO2013028208A1 (en) | 2011-08-25 | 2013-02-28 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
US9180228B2 (en) * | 2011-10-03 | 2015-11-10 | Abbott Cardiovascular Systems Inc. | Rubber toughened bioresorbable polymer peripheral scaffolds |
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WO2013183058A2 (en) | 2012-06-07 | 2013-12-12 | Tulip Medical Ltd. | Expanded device |
CN104363922B (zh) | 2012-06-14 | 2017-06-30 | 微仙美国有限公司 | 聚合物治疗组合物 |
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-
2006
- 2006-03-22 US US11/386,273 patent/US20070224234A1/en not_active Abandoned
-
2007
- 2007-03-05 AT AT07752364T patent/ATE535267T1/de active
- 2007-03-05 CA CA002646751A patent/CA2646751A1/en not_active Abandoned
- 2007-03-05 EP EP07752364A patent/EP2007447B1/en not_active Not-in-force
- 2007-03-05 JP JP2009501433A patent/JP5340913B2/ja not_active Expired - Fee Related
- 2007-03-05 WO PCT/US2007/005654 patent/WO2007111808A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US20070224234A1 (en) | 2007-09-27 |
ATE535267T1 (de) | 2011-12-15 |
CA2646751A1 (en) | 2007-10-04 |
WO2007111808A3 (en) | 2008-08-07 |
EP2007447B1 (en) | 2011-11-30 |
EP2007447A2 (en) | 2008-12-31 |
WO2007111808A2 (en) | 2007-10-04 |
JP2009530023A (ja) | 2009-08-27 |
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