JP2010522624A5 - - Google Patents
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- Publication number
- JP2010522624A5 JP2010522624A5 JP2010501217A JP2010501217A JP2010522624A5 JP 2010522624 A5 JP2010522624 A5 JP 2010522624A5 JP 2010501217 A JP2010501217 A JP 2010501217A JP 2010501217 A JP2010501217 A JP 2010501217A JP 2010522624 A5 JP2010522624 A5 JP 2010522624A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- component
- medical device
- layer
- bioerodible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920000642 polymer Polymers 0.000 claims 23
- 239000010410 layer Substances 0.000 claims 20
- 229920006125 amorphous polymer Polymers 0.000 claims 16
- 229920013641 bioerodible polymer Polymers 0.000 claims 16
- 239000000178 monomer Substances 0.000 claims 15
- 239000003814 drug Substances 0.000 claims 10
- 229940124597 therapeutic agent Drugs 0.000 claims 9
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 8
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 claims 4
- 235000014655 lactic acid Nutrition 0.000 claims 4
- 239000004310 lactic acid Substances 0.000 claims 4
- 239000000758 substrate Substances 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- 229920005689 PLLA-PGA Polymers 0.000 claims 2
- 239000003146 anticoagulant agent Substances 0.000 claims 2
- 229920000229 biodegradable polyester Polymers 0.000 claims 2
- 239000004622 biodegradable polyester Substances 0.000 claims 2
- 230000010261 cell growth Effects 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000013047 polymeric layer Substances 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 210000005167 vascular cell Anatomy 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims 1
- 229940035674 anesthetics Drugs 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000002095 anti-migrative effect Effects 0.000 claims 1
- 230000002927 anti-mitotic effect Effects 0.000 claims 1
- 230000000118 anti-neoplastic effect Effects 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 230000002785 anti-thrombosis Effects 0.000 claims 1
- 239000003529 anticholesteremic agent Substances 0.000 claims 1
- 229940127226 anticholesterol agent Drugs 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 239000003080 antimitotic agent Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229940034982 antineoplastic agent Drugs 0.000 claims 1
- 229920002988 biodegradable polymer Polymers 0.000 claims 1
- 239000004621 biodegradable polymer Substances 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 239000003193 general anesthetic agent Substances 0.000 claims 1
- 239000003966 growth inhibitor Substances 0.000 claims 1
- 239000007952 growth promoter Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 230000008520 organization Effects 0.000 claims 1
- 229940124549 vasodilator Drugs 0.000 claims 1
- 239000003071 vasodilator agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92039407P | 2007-03-28 | 2007-03-28 | |
| PCT/US2008/058407 WO2008121702A2 (en) | 2007-03-28 | 2008-03-27 | Medical devices having bioerodable layers for the release of therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522624A JP2010522624A (ja) | 2010-07-08 |
| JP2010522624A5 true JP2010522624A5 (enExample) | 2011-05-19 |
Family
ID=39808861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010501217A Pending JP2010522624A (ja) | 2007-03-28 | 2008-03-27 | 治療剤の放出のための生体侵食性層を有する医療装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090074838A1 (enExample) |
| EP (1) | EP2134380A2 (enExample) |
| JP (1) | JP2010522624A (enExample) |
| WO (1) | WO2008121702A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8057876B2 (en) * | 2008-02-25 | 2011-11-15 | Abbott Cardiovascular Systems Inc. | Bioabsorbable stent with layers having different degradation rates |
| US8653155B2 (en) * | 2009-08-13 | 2014-02-18 | Boston Scientific Scimed, Inc. | Polymers having lipophilic hydrocarbon and biodegradable polymeric segments |
| US8685433B2 (en) * | 2010-03-31 | 2014-04-01 | Abbott Cardiovascular Systems Inc. | Absorbable coating for implantable device |
| WO2014205346A1 (en) * | 2013-06-21 | 2014-12-24 | Boston Scientific Scimed, Inc. | Stent with deflecting connector |
| CN104587534A (zh) * | 2013-10-31 | 2015-05-06 | 先健科技(深圳)有限公司 | 可吸收铁基合金支架 |
| CN103933620B (zh) * | 2014-04-09 | 2015-09-16 | 北京颐合恒瑞医疗科技有限公司 | 一种可吸收皮肤缝合钉及制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5464450A (en) * | 1991-10-04 | 1995-11-07 | Scimed Lifesystems Inc. | Biodegradable drug delivery vascular stent |
| US6663881B2 (en) * | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5824048A (en) * | 1993-04-26 | 1998-10-20 | Medtronic, Inc. | Method for delivering a therapeutic substance to a body lumen |
| DE19608423A1 (de) * | 1996-03-05 | 1997-09-11 | Merck Patent Gmbh | Implantate mit phasenweiser Arzneistoffabgabe |
| WO1998056312A1 (en) * | 1997-06-13 | 1998-12-17 | Scimed Life Systems, Inc. | Stents having multiple layers of biodegradable polymeric composition |
| US6368658B1 (en) * | 1999-04-19 | 2002-04-09 | Scimed Life Systems, Inc. | Coating medical devices using air suspension |
| US6258121B1 (en) * | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
| US6338739B1 (en) * | 1999-12-22 | 2002-01-15 | Ethicon, Inc. | Biodegradable stent |
| US6545097B2 (en) * | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
| US20040220660A1 (en) * | 2001-02-05 | 2004-11-04 | Shanley John F. | Bioresorbable stent with beneficial agent reservoirs |
| US20030050687A1 (en) * | 2001-07-03 | 2003-03-13 | Schwade Nathan D. | Biocompatible stents and method of deployment |
| WO2003099169A1 (en) * | 2002-05-20 | 2003-12-04 | Orbus Medical Technologies Inc. | Drug eluting implantable medical device |
| US20070078513A1 (en) * | 2002-09-18 | 2007-04-05 | Medtronic Vascular, Inc. | Controllable drug releasing gradient coatings for medical devices |
| KR20060028695A (ko) * | 2003-06-16 | 2006-03-31 | 난양 테크놀러지컬 유니버시티 | 고분자 스텐트 및 이의 제조 방법 |
| CN101141933B (zh) * | 2004-03-10 | 2015-07-29 | 祥丰医疗有限公司 | 内皮配体结合涂覆的医疗装置 |
| WO2006002365A2 (en) * | 2004-06-24 | 2006-01-05 | Angiotech International Ag | Microparticles with high loadings of a bioactive agent |
| WO2006027994A1 (ja) * | 2004-09-08 | 2006-03-16 | Kaneka Corporation | 生体留置用ステント |
| KR100705210B1 (ko) * | 2004-09-23 | 2007-04-06 | 주식회사 한독약품 | 경구투여를 위한 당뇨병 치료용 약제학적 복합제제 |
| US20060147491A1 (en) * | 2005-01-05 | 2006-07-06 | Dewitt David M | Biodegradable coating compositions including multiple layers |
| US20060198868A1 (en) * | 2005-01-05 | 2006-09-07 | Dewitt David M | Biodegradable coating compositions comprising blends |
| US8075906B2 (en) * | 2005-02-01 | 2011-12-13 | Boston Scientific Scimed, Inc. | Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species |
| PT1883665T (pt) * | 2005-04-22 | 2017-11-14 | Univ Geneve | Composições polilactídeo e usos das mesmas |
| US8778375B2 (en) * | 2005-04-29 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Amorphous poly(D,L-lactide) coating |
| US9248219B2 (en) * | 2007-09-14 | 2016-02-02 | Boston Scientific Scimed, Inc. | Medical devices having bioerodable layers for the release of therapeutic agents |
-
2008
- 2008-03-27 WO PCT/US2008/058407 patent/WO2008121702A2/en not_active Ceased
- 2008-03-27 JP JP2010501217A patent/JP2010522624A/ja active Pending
- 2008-03-27 EP EP08732921A patent/EP2134380A2/en not_active Withdrawn
- 2008-03-27 US US12/056,689 patent/US20090074838A1/en not_active Abandoned
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