JP2010522153A5 - - Google Patents
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- Publication number
- JP2010522153A5 JP2010522153A5 JP2009554085A JP2009554085A JP2010522153A5 JP 2010522153 A5 JP2010522153 A5 JP 2010522153A5 JP 2009554085 A JP2009554085 A JP 2009554085A JP 2009554085 A JP2009554085 A JP 2009554085A JP 2010522153 A5 JP2010522153 A5 JP 2010522153A5
- Authority
- JP
- Japan
- Prior art keywords
- crystal
- forming compound
- propiconazole
- group
- crystal forming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000013078 crystal Substances 0.000 claims 24
- 150000001875 compounds Chemical class 0.000 claims 14
- 239000005822 Propiconazole Substances 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 claims 6
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims 5
- DHLUJPLHLZJUBW-UHFFFAOYSA-N 6-methylpyridin-3-ol Chemical compound CC1=CC=C(O)C=N1 DHLUJPLHLZJUBW-UHFFFAOYSA-N 0.000 claims 4
- 125000002947 alkylene group Chemical group 0.000 claims 4
- 125000000524 functional group Chemical group 0.000 claims 4
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- BZUNJUAMQZRJIP-UHFFFAOYSA-N 15-hydroxypentadecanoic acid Chemical compound OCCCCCCCCCCCCCCC(O)=O BZUNJUAMQZRJIP-UHFFFAOYSA-N 0.000 claims 2
- 229930185605 Bisphenol Natural products 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 claims 2
- 230000000855 fungicidal effect Effects 0.000 claims 2
- 239000012770 industrial material Substances 0.000 claims 2
- VFQXVTODMYMSMJ-UHFFFAOYSA-N isonicotinamide Chemical compound NC(=O)C1=CC=NC=C1 VFQXVTODMYMSMJ-UHFFFAOYSA-N 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- DGQOCLATAPFASR-UHFFFAOYSA-N tetrahydroxy-1,4-benzoquinone Chemical compound OC1=C(O)C(=O)C(O)=C(O)C1=O DGQOCLATAPFASR-UHFFFAOYSA-N 0.000 claims 2
- ALVZNPYWJMLXKV-UHFFFAOYSA-N 1,9-Nonanediol Chemical compound OCCCCCCCCCO ALVZNPYWJMLXKV-UHFFFAOYSA-N 0.000 claims 1
- DNCYBUMDUBHIJZ-UHFFFAOYSA-N 1h-pyrimidin-6-one Chemical compound O=C1C=CN=CN1 DNCYBUMDUBHIJZ-UHFFFAOYSA-N 0.000 claims 1
- JEAVIRYCMBDJIU-UHFFFAOYSA-N 6-methyl-1h-pyridin-2-one Chemical compound CC1=CC=CC(O)=N1 JEAVIRYCMBDJIU-UHFFFAOYSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 206010017533 Fungal infection Diseases 0.000 claims 1
- 241000023320 Luma <angiosperm> Species 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- 208000031888 Mycoses Diseases 0.000 claims 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 239000012872 agrochemical composition Substances 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- VCCBEIPGXKNHFW-UHFFFAOYSA-N biphenyl-4,4'-diol Chemical group C1=CC(O)=CC=C1C1=CC=C(O)C=C1 VCCBEIPGXKNHFW-UHFFFAOYSA-N 0.000 claims 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 claims 1
- 230000008025 crystallization Effects 0.000 claims 1
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 150000002576 ketones Chemical class 0.000 claims 1
- WFJRIDQGVSJLLH-UHFFFAOYSA-N methyl n-aminocarbamate Chemical compound COC(=O)NN WFJRIDQGVSJLLH-UHFFFAOYSA-N 0.000 claims 1
- 229960003966 nicotinamide Drugs 0.000 claims 1
- 235000005152 nicotinamide Nutrition 0.000 claims 1
- 239000011570 nicotinamide Substances 0.000 claims 1
- 230000000361 pesticidal effect Effects 0.000 claims 1
- 239000003090 pesticide formulation Substances 0.000 claims 1
- 150000003141 primary amines Chemical class 0.000 claims 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims 1
- 150000003335 secondary amines Chemical class 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 239000004546 suspension concentrate Substances 0.000 claims 1
- 150000003512 tertiary amines Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0705657A GB0705657D0 (en) | 2007-03-23 | 2007-03-23 | Co-Crystals |
| GB0705659A GB0705659D0 (en) | 2007-03-23 | 2007-03-23 | Co-Crystals |
| PCT/GB2008/001019 WO2008117037A1 (en) | 2007-03-23 | 2008-03-20 | Co-crystals of propiconazole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522153A JP2010522153A (ja) | 2010-07-01 |
| JP2010522153A5 true JP2010522153A5 (https=) | 2011-03-24 |
Family
ID=39472667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009554085A Ceased JP2010522153A (ja) | 2007-03-23 | 2008-03-20 | 共結晶 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8318789B2 (https=) |
| EP (1) | EP2139885B1 (https=) |
| JP (1) | JP2010522153A (https=) |
| CN (1) | CN101679389B (https=) |
| AT (1) | ATE490962T1 (https=) |
| CA (1) | CA2680351A1 (https=) |
| DE (1) | DE602008003911D1 (https=) |
| RU (1) | RU2462465C2 (https=) |
| WO (1) | WO2008117037A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0817513D0 (en) | 2008-09-24 | 2008-10-29 | Syngenta Ltd | Co-crystals |
| KR20120115492A (ko) * | 2009-11-06 | 2012-10-18 | 바스프 에스이 | ４―히드록시 벤조산 및 선택된 살충제의 결정질 복합체 |
| US8318807B2 (en) | 2010-02-03 | 2012-11-27 | Laurus Labs Private Limited | Pterostilbene cocrystals |
| GB201006326D0 (en) * | 2010-04-15 | 2010-06-02 | Syngenta Ltd | Formulation |
| CN102188365B (zh) * | 2011-05-11 | 2012-12-05 | 中山大学 | 一种难溶性药物共晶固体分散体及其制备方法 |
| US9895371B2 (en) | 2014-06-24 | 2018-02-20 | Viktor Veniaminovich Tets | Fungicidal agent |
| CN104557733A (zh) * | 2015-01-05 | 2015-04-29 | 哈尔滨医科大学 | 异烟酰胺为前驱体的5-氟尿嘧啶药物共晶及其制备方法和应用 |
| RU2595870C1 (ru) | 2015-08-04 | 2016-08-27 | Виктор Вениаминович Тец | Средство против грибковых инфекций |
| CN107915561B (zh) * | 2017-12-07 | 2020-03-24 | 中国工程物理研究院化工材料研究所 | 硝仿联三唑共晶炸药及其制备方法 |
| US11632956B2 (en) | 2017-12-20 | 2023-04-25 | Upl Ltd | Co-crystals of boscalid and triazoles |
| CN108997235A (zh) * | 2018-07-01 | 2018-12-14 | 王新民 | 一种高溶解度植物生长调节剂及其制备方法 |
| CN110183310A (zh) * | 2019-06-05 | 2019-08-30 | 西北师范大学 | 利用超声辅助共结晶法制备白藜芦醇药物共晶的方法 |
| JP2021054781A (ja) * | 2019-09-26 | 2021-04-08 | デボン エルエス，リミテッド | 共結晶形エフィナコナゾール、及びその製造方法 |
| CN113402575B (zh) * | 2021-06-18 | 2022-04-22 | 邦泰生物工程(深圳)有限公司 | 一种制备烟酰胺单核苷酸共晶体的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ179111A (en) * | 1974-11-18 | 1978-03-06 | Janssen Pharmaceutica Nv | I-(aryl)-ethyl-1h-1,2,4-triazole ketals,anti-microbial and plant growth controlling compositions |
| BE879215A (nl) * | 1978-10-06 | 1980-04-08 | Janssen Pharmaceutica Nv | Nieuwe antimicrobiele triazoolderivaten |
| IT1186784B (it) * | 1985-11-04 | 1987-12-16 | Montedison Spa | Azoliderivati ad attivita' antufungina |
| US4940799A (en) * | 1987-07-20 | 1990-07-10 | Ciba-Geigy Corporation | Preparation of the diastereomeric mixture 2R,4S-1-[2-(2,4-dichlorophenyl)-4-n-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole |
| ES2117748T3 (es) * | 1993-11-16 | 1998-08-16 | Bayer Ag | Empleo de esteres del acido fosforico como inhibidores de cristalizacion. |
| BR9607957A (pt) * | 1995-03-08 | 1998-07-14 | Du Pont | Composição fungicida e método de tratamento de um local para controlar patógenos fúngicos |
| JP3838661B2 (ja) * | 1995-11-29 | 2006-10-25 | ローヌ−プーラン・アグロシミ | 昆虫類防除用の乳化性組成物 |
| DE19751631A1 (de) * | 1997-11-21 | 1999-05-27 | Bayer Ag | Verwendung von Cyclodextrin-Komplexen zur Applikation von agrochemischen Wirkstoffen in den Saftstrom von Pflanzen |
| DE19751630A1 (de) * | 1997-11-21 | 1999-05-27 | Bayer Ag | Inklusionskomplexe aus modifizierten Kohlenhydraten und agrochemischen Wirkstoffen |
| JP5069905B2 (ja) * | 2003-01-21 | 2012-11-07 | アプテュイト （ウエスト ラファイエット）、エルエルシー | 新規な共結晶化 |
| WO2006007448A2 (en) * | 2004-06-17 | 2006-01-19 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions and related methods of use |
| CN101069501A (zh) * | 2007-05-28 | 2007-11-14 | 江苏龙灯化学有限公司 | 双取代长链烷基酰胺类作为结晶抑制剂在唑类农药液剂中的应用 |
-
2008
- 2008-03-20 JP JP2009554085A patent/JP2010522153A/ja not_active Ceased
- 2008-03-20 EP EP08718856A patent/EP2139885B1/en not_active Not-in-force
- 2008-03-20 DE DE602008003911T patent/DE602008003911D1/de active Active
- 2008-03-20 CA CA002680351A patent/CA2680351A1/en not_active Abandoned
- 2008-03-20 RU RU2009139066/04A patent/RU2462465C2/ru not_active IP Right Cessation
- 2008-03-20 US US12/532,212 patent/US8318789B2/en not_active Expired - Fee Related
- 2008-03-20 WO PCT/GB2008/001019 patent/WO2008117037A1/en not_active Ceased
- 2008-03-20 AT AT08718856T patent/ATE490962T1/de not_active IP Right Cessation
- 2008-03-20 CN CN200880009323XA patent/CN101679389B/zh not_active Expired - Fee Related
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