JP2010520290A5 - - Google Patents

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Publication number
JP2010520290A5
JP2010520290A5 JP2009552761A JP2009552761A JP2010520290A5 JP 2010520290 A5 JP2010520290 A5 JP 2010520290A5 JP 2009552761 A JP2009552761 A JP 2009552761A JP 2009552761 A JP2009552761 A JP 2009552761A JP 2010520290 A5 JP2010520290 A5 JP 2010520290A5
Authority
JP
Japan
Prior art keywords
epha3
antibody
pharmaceutical composition
composition according
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009552761A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010520290A (ja
JP5311060B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/003149 external-priority patent/WO2008112192A2/en
Publication of JP2010520290A publication Critical patent/JP2010520290A/ja
Publication of JP2010520290A5 publication Critical patent/JP2010520290A5/ja
Application granted granted Critical
Publication of JP5311060B2 publication Critical patent/JP5311060B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009552761A 2007-03-08 2008-03-10 固形腫瘍の治療のためのEphA3抗体 Active JP5311060B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89384807P 2007-03-08 2007-03-08
US60/893,848 2007-03-08
PCT/US2008/003149 WO2008112192A2 (en) 2007-03-08 2008-03-10 Epha3 antibodies for the treatment of solid tumors

Publications (3)

Publication Number Publication Date
JP2010520290A JP2010520290A (ja) 2010-06-10
JP2010520290A5 true JP2010520290A5 (index.php) 2011-04-21
JP5311060B2 JP5311060B2 (ja) 2013-10-09

Family

ID=39689392

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009552761A Active JP5311060B2 (ja) 2007-03-08 2008-03-10 固形腫瘍の治療のためのEphA3抗体

Country Status (13)

Country Link
US (1) US8637016B2 (index.php)
EP (2) EP2136838B1 (index.php)
JP (1) JP5311060B2 (index.php)
CN (1) CN101641115B (index.php)
AU (1) AU2008226905C1 (index.php)
CA (1) CA2679986C (index.php)
DK (1) DK3199180T3 (index.php)
ES (1) ES2910298T3 (index.php)
IL (1) IL200764A (index.php)
NZ (1) NZ579478A (index.php)
PL (1) PL3199180T3 (index.php)
PT (1) PT3199180T (index.php)
WO (1) WO2008112192A2 (index.php)

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US8470966B2 (en) 2007-08-10 2013-06-25 Protelica, Inc. Universal fibronectin type III binding-domain libraries
NZ594950A (en) * 2009-03-06 2013-06-28 Kalobios Pharmaceuticals Inc Treatment of leukemias and chronic myeloproliferative diseases with antibodies to epha3
PT2488554T (pt) 2009-10-14 2019-09-13 Humanigen Inc Anticorpos para epha3
US20110243934A1 (en) * 2010-04-01 2011-10-06 Kalobios Pharmaceuticals Inc. Epha3 antibodies for the treatment of multiple myeloma
CA2802723A1 (en) * 2010-06-18 2011-12-22 Kalobios Pharmaceuticals, Inc. Detection of epha3 as a marker of the presence of a solid tumor
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CN107903325B (zh) 2011-05-16 2021-10-29 埃泰美德(香港)有限公司 多特异性fab融合蛋白及其使用方法
CN104254340A (zh) * 2011-08-12 2014-12-31 卡罗生物制药股份有限公司 通过靶向骨髓中异常血管系统上表达的EphA3来治疗血液增殖性疾病的方法
EP3068797B1 (en) 2013-11-11 2020-01-08 Wake Forest University Health Sciences Constructs for multi-valent targeting of tumors
AU2017233121B2 (en) 2016-03-15 2023-12-21 Itabmed (Hk) Limited Multispecific Fab fusion proteins and use thereof
CN112867735B (zh) 2018-09-07 2025-05-09 埃泰美德(香港)有限公司 双特异性抗原结合蛋白及其用途
JP2022552786A (ja) * 2019-10-09 2022-12-20 ザ・カウンシル・オヴ・ザ・クイーンズランド・インスティテュート・オヴ・メディカル・リサーチ 標的化epha3及びその使用

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