JP2010519939A - 少なくとも1つの薬剤の注入のための装置 - Google Patents
少なくとも1つの薬剤の注入のための装置 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
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- A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
【選択図】図1
Description
それ故、「PPVを最大化すること」(「1回排出量を最大化すること」のための代理として)が、外科手術処理の間に、臨床目的として選ばれたとき、図3に示されるアルゴリズムが、閉ループコントローラシステムによって適用され得る。
は、オーバラップする2つの動作領域によって生じ、1以上の薬剤の注入を増加させ、又は減少させるように指示する。判断ツリーで促されることが不可能である処置は、例えば図10における曲線をなす特性要因図で実現される。
Claims (8)
- 少なくとも2つの薬剤(20,40)が注入されるようにするための少なくとも2つのアクチュエータ(10,20)、
少なくとも2つのパラメータを測定するための少なくとも1つのセンサ(50,54)、
アクチュエータ(10,20)を制御するためのコントローラ(60)、を含み、
コントローラ(60)が、2つのパラメータの値に従ってアクチュエータを作動させるようにプラグラムされる少なくとも1つの薬剤の注入のための装置(1)であって、
コントローラが薬剤の依存性を考慮して設けられる少なくとも1つの薬剤の注入のための装置。 - パラメータは、収縮期動脈圧(SAP)、平均動脈圧(MAP)、パルス酸素濃度プレチスモグラフ波形変動(POPV)、ヘモグロビン(Hb)、ヘマトクリット(hct)、心拍数(HR)、脈圧変動(PPV)、収縮期圧変動(SPV)、前駆出期変動(PEPV)及び中心静脈酸素飽和度(ScVO2)のグループから選択される請求項1に記載の装置。
- 薬剤は、流体、赤血球、血管作用剤、及び陽性的に変力的な作用剤、のグループから選択される請求項1又は2に記載の装置。
- コントローラ(60)は、
薬剤(20,40)の最大投与量についての値を含む最大メモリ(91)、
注入される薬剤(20,40)の投与量を決定するための投与量決定装置(92)、及び
注入された薬剤が最大投与量に達した場合に、薬剤(20,40)の注入を停止するための最大ストッパ(93)、
を含むマキシマム装置(90)をさらに含む請求項1から3のいずれか1項に記載の装置。 - コントローラ(60)は、
薬剤(20,40)のリスト及び対応する期待されるパラメータ変化を保存するための効果メモリ(101)、
及び、薬剤(20,40)の注入を停止するためのストッパ(102)、
を含む効果制御装置(100)をさらに含み、
効果制御装置(100)は、薬剤(20,40)が注入され、そして、少なくとも1つの対応する期待されるパラメータ変化が生じない場合に、ストッパ(102)を作動するようにプログラムされる請求項1から4のいずれか1項に記載の装置。 - コントローラ(60)は、
閾値(126)と、実際に測定されるパラメータによって定められるパラメータポジション(127)との間の距離を決定する距離分析器(80)、
及び、距離を薬剤(20,40)の投与量に変換するための変換ユニット(81)、
を備え、かつ、コントローラ(60)が薬剤(20,40)のこの投与量によりアクチュエータ(10,30)を作動させるようにプログラムされる請求項1から5のいずれか1項に記載の装置。 - コントローラ(60)が閉ループコントローラである請求項1から6のいずれか1項に記載の装置。
- 少なくとも2つのパラメータを測定すること、
少なくとも2つの薬剤(20,40)を2つのパラメータの値に従って注入されるようにすること、を含む少なくとも1つの薬剤の注入のための方法であって、
薬剤の依存性が考慮される少なくとも1つ薬剤の注入のための方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007010326.5 | 2007-03-02 | ||
DE102007010326A DE102007010326A1 (de) | 2007-03-02 | 2007-03-02 | Vorrichtung zur Infusion von mindestens einem Medikament |
PCT/EP2008/001624 WO2008107127A1 (en) | 2007-03-02 | 2008-02-29 | Device for infusion of at least two medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010519939A true JP2010519939A (ja) | 2010-06-10 |
JP5604112B2 JP5604112B2 (ja) | 2014-10-08 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2009551140A Active JP5604112B2 (ja) | 2007-03-02 | 2008-02-29 | 少なくとも1つの薬剤の注入のための装置 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8608683B2 (ja) |
EP (1) | EP2131897B1 (ja) |
JP (1) | JP5604112B2 (ja) |
DE (1) | DE102007010326A1 (ja) |
WO (1) | WO2008107127A1 (ja) |
Cited By (1)
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KR101914049B1 (ko) * | 2010-09-15 | 2018-11-02 | 싱가포르 헬스 서비시즈 피티이. 엘티디. | 약물 주입장치 및 혈압 조절방법 |
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US8956291B2 (en) | 2005-02-22 | 2015-02-17 | Admetsys Corporation | Balanced physiological monitoring and treatment system |
WO2010006047A2 (en) * | 2008-07-10 | 2010-01-14 | Ethicon Endo-Surgery, Inc. | Medical system which controls delivery of a drug and which includes a backpack pouch |
WO2010011805A1 (en) * | 2008-07-24 | 2010-01-28 | Admetsys Corporation | Device and method for automatically sampling and measuring blood analytes |
US9480789B2 (en) | 2009-06-01 | 2016-11-01 | Ethicon Endo-Surgery, Inc. | Method and sedation delivery system including a pump assembly and a co-formulation of first and second drugs |
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PL2482870T3 (pl) | 2009-09-29 | 2018-05-30 | Admetsys Corporation | System i sposób rozróżniania pojemników w podawaniu leków |
US8568327B2 (en) * | 2010-04-30 | 2013-10-29 | Lidco Group, Plc | Monitoring device and method |
AU2015258349B2 (en) * | 2010-09-15 | 2017-12-21 | Singapore Health Services Pte Ltd. | Drug infusion system and method for controlling blood pressure |
DE102010054361B4 (de) * | 2010-12-13 | 2013-02-21 | Nli Gmbh | Therapiegerät |
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US20140081098A1 (en) * | 2012-09-14 | 2014-03-20 | Nellcor Puritan Bennett Llc | Sensor system |
US20150217056A1 (en) * | 2013-12-31 | 2015-08-06 | Stratos Group Llc | Therapy systems and methods utilizing tissue oxygenation detection |
GB2537629B (en) * | 2015-04-21 | 2017-06-28 | Gen Electric | System and method for controlling a valve of a portable medical device |
BR112019012214A8 (pt) | 2016-12-15 | 2023-03-28 | Baxter Int | Sistema e método para monitorar e determinar parâmetros do paciente a partir de forma de onda venosa detectada |
US20190133886A1 (en) * | 2017-11-09 | 2019-05-09 | Kristine Brecht | System and method for dispensing medication |
FR3075652B1 (fr) * | 2017-12-22 | 2022-04-22 | Univ Pierre Et Marie Curie Paris 6 | Dispositif d'administration automatisee d'un vasopresseur et d'un liquide de remplissage vasculaire |
US11039754B2 (en) | 2018-05-14 | 2021-06-22 | Baxter International Inc. | System and method for monitoring and determining patient parameters from sensed venous waveform |
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- 2008-02-29 JP JP2009551140A patent/JP5604112B2/ja active Active
- 2008-02-29 US US12/529,493 patent/US8608683B2/en active Active
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KR101914049B1 (ko) * | 2010-09-15 | 2018-11-02 | 싱가포르 헬스 서비시즈 피티이. 엘티디. | 약물 주입장치 및 혈압 조절방법 |
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EP2131897B1 (en) | 2019-12-04 |
US8608683B2 (en) | 2013-12-17 |
US20100137828A1 (en) | 2010-06-03 |
EP2131897A1 (en) | 2009-12-16 |
WO2008107127A1 (en) | 2008-09-12 |
DE102007010326A1 (de) | 2008-09-04 |
JP5604112B2 (ja) | 2014-10-08 |
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