JP2010518139A5 - - Google Patents

Info

Publication number

JP2010518139A5

JP2010518139A5 JP2009549396A JP2009549396A JP2010518139A5 JP 2010518139 A5 JP2010518139 A5 JP 2010518139A5 JP 2009549396 A JP2009549396 A JP 2009549396A JP 2009549396 A JP2009549396 A JP 2009549396A JP 2010518139 A5 JP2010518139 A5 JP 2010518139A5

Authority

JP

Japan

Prior art keywords

chitosan

physiologically acceptable

acceptable salt

aminopolysaccharide

amino

Prior art date

2008-02-07

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 229920001661 Chitosan Polymers 0.000 claims 18
• 150000003839 salts Chemical class 0.000 claims 13
• 229920001282 polysaccharide Polymers 0.000 claims 9
• 239000005017 polysaccharide Substances 0.000 claims 9
• -1 Amino polysaccharides Chemical class 0.000 claims 8
• 239000004480 active ingredient Substances 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 238000009472 formulation Methods 0.000 claims 3
• 239000000203 mixture Substances 0.000 claims 3
• WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 2
• 229940079593 drug Drugs 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 208000027866 inflammatory disease Diseases 0.000 claims 2
• YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 2
• BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 1
• 239000005711 Benzoic acid Substances 0.000 claims 1
• VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 claims 1
• PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical group CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 1
• 108010036949 Cyclosporine Proteins 0.000 claims 1
• 206010012438 Dermatitis atopic Diseases 0.000 claims 1
• 241000195955 Equisetum hyemale Species 0.000 claims 1
• 241000207963 Harpagophytum Species 0.000 claims 1
• 206010028703 Nail psoriasis Diseases 0.000 claims 1
• OGQICQVSFDPSEI-UHFFFAOYSA-N Zorac Chemical compound N1=CC(C(=O)OCC)=CC=C1C#CC1=CC=C(SCCC2(C)C)C2=C1 OGQICQVSFDPSEI-UHFFFAOYSA-N 0.000 claims 1
• 229960001138 acetylsalicylic acid Drugs 0.000 claims 1
• 229960005339 acitretin Drugs 0.000 claims 1
• IHUNBGSDBOWDMA-AQFIFDHZSA-N all-trans-acitretin Chemical compound COC1=CC(C)=C(\C=C\C(\C)=C\C=C\C(\C)=C\C(O)=O)C(C)=C1C IHUNBGSDBOWDMA-AQFIFDHZSA-N 0.000 claims 1
• SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 1
• 208000004631 alopecia areata Diseases 0.000 claims 1
• 230000002682 anti-psoriatic effect Effects 0.000 claims 1
• 230000002421 anti-septic effect Effects 0.000 claims 1
• 229940064004 antiseptic throat preparations Drugs 0.000 claims 1
• 201000008937 atopic dermatitis Diseases 0.000 claims 1
• 235000010233 benzoic acid Nutrition 0.000 claims 1
• 229960002537 betamethasone Drugs 0.000 claims 1
• UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
• 229960004436 budesonide Drugs 0.000 claims 1
• 229960005084 calcitriol Drugs 0.000 claims 1
• GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 claims 1
• 235000020964 calcitriol Nutrition 0.000 claims 1
• 239000011612 calcitriol Substances 0.000 claims 1
• 229960001265 ciclosporin Drugs 0.000 claims 1
• 229960002842 clobetasol Drugs 0.000 claims 1
• CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 claims 1
• 239000003246 corticosteroid Substances 0.000 claims 1
• 229960001334 corticosteroids Drugs 0.000 claims 1
• 239000006071 cream Substances 0.000 claims 1
• 229930182912 cyclosporin Natural products 0.000 claims 1
• DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims 1
• 229960001259 diclofenac Drugs 0.000 claims 1
• 239000006260 foam Substances 0.000 claims 1
• 239000000499 gel Substances 0.000 claims 1
• 125000002768 hydroxyalkyl group Chemical group 0.000 claims 1
• 229940054190 hydroxypropyl chitosan Drugs 0.000 claims 1
• 239000003018 immunosuppressive agent Substances 0.000 claims 1
• 229940125721 immunosuppressive agent Drugs 0.000 claims 1
• 239000003410 keratolytic agent Substances 0.000 claims 1
• DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 claims 1
• 229960000991 ketoprofen Drugs 0.000 claims 1
• 239000004922 lacquer Substances 0.000 claims 1
• 201000011486 lichen planus Diseases 0.000 claims 1
• 239000006210 lotion Substances 0.000 claims 1
• 230000003020 moisturizing effect Effects 0.000 claims 1
• 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
• 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
• 239000002674 ointment Substances 0.000 claims 1
• FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 1
• 239000000419 plant extract Substances 0.000 claims 1
• 229960004889 salicylic acid Drugs 0.000 claims 1
• 239000007921 spray Substances 0.000 claims 1
• 238000005728 strengthening Methods 0.000 claims 1
• 229960000565 tazarotene Drugs 0.000 claims 1
• 239000012049 topical pharmaceutical composition Substances 0.000 claims 1
• 229960001727 tretinoin Drugs 0.000 claims 1