JP2010518120A - ７−エチル−１０−ヒドロキシカンプトテシンのマルチアームポリマー複合体を用いた抵抗性または難治性の癌の治療方法 - Google Patents

７−エチル−１０−ヒドロキシカンプトテシンのマルチアームポリマー複合体を用いた抵抗性または難治性の癌の治療方法 Download PDF

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JP2010518120A
JP2010518120A JP2009549259A JP2009549259A JP2010518120A JP 2010518120 A JP2010518120 A JP 2010518120A JP 2009549259 A JP2009549259 A JP 2009549259A JP 2009549259 A JP2009549259 A JP 2009549259A JP 2010518120 A JP2010518120 A JP 2010518120A
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cancer
substituted
refractory
resistant
acid
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JP2010518120A5 (https=
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ザオ，ホン
サプラ，プジャ
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Enzon Pharmaceuticals Inc
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Enzon Pharmaceuticals Inc
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61P3/00—Drugs for disorders of the metabolism
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JP2009549259A 2007-02-09 2008-02-08 ７−エチル−１０−ヒドロキシカンプトテシンのマルチアームポリマー複合体を用いた抵抗性または難治性の癌の治療方法 Pending JP2010518120A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90059207P 2007-02-09 2007-02-09
PCT/US2008/053438 WO2008098178A2 (en) 2007-02-09 2008-02-08 Treatment of resistant or refractory cancers with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin

Publications (2)

Publication Number Publication Date
JP2010518120A true JP2010518120A (ja) 2010-05-27
JP2010518120A5 JP2010518120A5 (https=) 2012-04-12

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JP2009549259A Pending JP2010518120A (ja) 2007-02-09 2008-02-08 ７−エチル−１０−ヒドロキシカンプトテシンのマルチアームポリマー複合体を用いた抵抗性または難治性の癌の治療方法

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US (2) US7928095B2 (https=)
EP (1) EP2109448B1 (https=)
JP (1) JP2010518120A (https=)
KR (1) KR20090108082A (https=)
CN (1) CN101605539B (https=)
AU (1) AU2008213576B2 (https=)
BR (1) BRPI0807232A2 (https=)
CA (1) CA2677798A1 (https=)
IL (1) IL200100A0 (https=)
MX (1) MX2009008549A (https=)
RU (1) RU2009133793A (https=)
TW (1) TW200902066A (https=)
WO (1) WO2008098178A2 (https=)

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CN110448533B (zh) * 2014-12-05 2022-03-29 天津键凯科技有限公司 一种聚乙二醇修饰的喜树碱类衍生物的药物组合物及其制备方法
CN108727584B (zh) * 2017-04-21 2021-01-05 博瑞生物医药（苏州）股份有限公司 抗癌偶联物
CN107670050B (zh) * 2017-08-30 2019-06-07 重庆阿普格雷生物科技有限公司 基于pki-587的抗癌中间体和聚乙二醇偶联抗癌药物、及其制备方法和应用
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IL200100A0 (en) 2010-04-15
US7928095B2 (en) 2011-04-19
AU2008213576A1 (en) 2008-08-14
BRPI0807232A2 (pt) 2014-04-29
AU2008213576B2 (en) 2013-01-17
EP2109448A2 (en) 2009-10-21
MX2009008549A (es) 2009-08-18
EP2109448A4 (en) 2011-04-13
US20080193408A1 (en) 2008-08-14
US20110195990A1 (en) 2011-08-11
AU2008213576A2 (en) 2009-09-03
CN101605539A (zh) 2009-12-16
KR20090108082A (ko) 2009-10-14
CA2677798A1 (en) 2008-08-14
RU2009133793A (ru) 2011-03-20
CN101605539B (zh) 2013-01-02

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