JP2010516254A5 - - Google Patents

Download PDF

Info

Publication number
JP2010516254A5
JP2010516254A5 JP2009546507A JP2009546507A JP2010516254A5 JP 2010516254 A5 JP2010516254 A5 JP 2010516254A5 JP 2009546507 A JP2009546507 A JP 2009546507A JP 2009546507 A JP2009546507 A JP 2009546507A JP 2010516254 A5 JP2010516254 A5 JP 2010516254A5
Authority
JP
Japan
Prior art keywords
ubiquitin
seq
uba6
biologically active
sirna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009546507A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010516254A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/051312 external-priority patent/WO2008089329A2/en
Publication of JP2010516254A publication Critical patent/JP2010516254A/ja
Publication of JP2010516254A5 publication Critical patent/JP2010516254A5/ja
Pending legal-status Critical Current

Links

JP2009546507A 2007-01-18 2008-01-17 ユビキチンに対する新規活性化および転移カスケード Pending JP2010516254A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88543107P 2007-01-18 2007-01-18
US94675707P 2007-06-28 2007-06-28
PCT/US2008/051312 WO2008089329A2 (en) 2007-01-18 2008-01-17 Novel activation and transfer cascade for ubiquitin

Publications (2)

Publication Number Publication Date
JP2010516254A JP2010516254A (ja) 2010-05-20
JP2010516254A5 true JP2010516254A5 (https=) 2013-12-26

Family

ID=39636707

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009546507A Pending JP2010516254A (ja) 2007-01-18 2008-01-17 ユビキチンに対する新規活性化および転移カスケード

Country Status (4)

Country Link
US (3) US8198059B2 (https=)
EP (1) EP2102657A4 (https=)
JP (1) JP2010516254A (https=)
WO (1) WO2008089329A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12059413B2 (en) 2016-11-02 2024-08-13 The Research Foundation For The State University Of New York Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction
EP3962933A1 (en) 2019-04-18 2022-03-09 Dana-Farber Cancer Institute, Inc. Selective targeting of ubiquitin- and ubiquitin-like e1-activating enzymes by structurally-stabilized peptides
WO2023218453A1 (en) * 2022-05-09 2023-11-16 Ramot At Tel-Aviv University Ltd. Methods of treating diseases associated with polyalanine expansion mutations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1320590A2 (en) * 2000-07-13 2003-06-25 Millennium Pharmaceuticals, Inc. 47885, a novel human ubiquitin-activating enzyme and uses therefor
US20040043386A1 (en) * 2002-08-30 2004-03-04 Todd Pray Methods and compositions for functional ubiquitin assays
RS52458B (sr) * 2005-02-04 2013-02-28 Millennium Pharmaceuticals Inc. Inhibitori e1 aktivirajućih enzima

Similar Documents

Publication Publication Date Title
Ye et al. A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
Willis et al. Signaling to and from the RNA polymerase III transcription and processing machinery
Turner et al. Function and fate of myofibroblasts after myocardial infarction
Stone et al. Genomics of human fibrotic diseases: disordered wound healing response
RU2019119609A (ru) Пептиды, способные реактивировать мутанты р53
CN118546256A (zh) 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法
Dai et al. SETD4 regulates cell quiescence and catalyzes the trimethylation of H4K20 during diapause formation in Artemia
BRPI0821088A2 (pt) construção de ácido nucléico, célula hospedeira microbiana transgênica, e, métodos para produzir um polipeptídeo tendo atividade de feruloil esterase, para produzir um mutante de uma célula-mãe, para inibir a expressão de um polipeptídeo tendo atividade de feruloil esterase em uma célula, para produzir uma proteína, e, para degradar um material contendo xilano.
CA2782676C (en) Pharmaceutical compositions for intracellular delivery of nucleic acids and proteins and uses thereof for treatment of ureca cycle metabolic disorders
JP2009528346A5 (https=)
CY1108689T1 (el) Ολιγοπεπτιδια για την ελαττωση αυξημενης συγκεντρωσεως της ουριας στο αιμα
JP2013529919A5 (https=)
Qiao et al. A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseases
JP2013507934A5 (https=)
WO2008098569A3 (de) Biologisch wirksame moleküle, insbesondere auf grundlage von pna und sirna, verfahren zu deren zellspezifischen aktivierung sowie applikationskit zur verabreichung
NZ602474A (en) Regeneration of pancreatic islets and reversal of diabetes by islet transcription factor genes delivered in vivo
WO2007015771A3 (en) Composition and method for introduction of rna interference sequences into targeted cells and tissues
Su et al. The influence of circadian rhythms on DNA damage repair in skin Photoaging
Yang et al. Cell volume regulation modulates macrophage-related inflammatory responses via JAK/STAT signaling pathways
Nicosia et al. Mimicking molecular pathways in the design of smart hydrogels for the design of vascularized engineered tissues
Li et al. Adenovirus-mediated LAMA3 transduction enhances hemidesmosome formation and periodontal reattachment during wound healing
JP2014527801A5 (https=)
Koli et al. Ribosomal dormancy at the nexus of ribosome homeostasis and protein synthesis
JP2010516254A5 (https=)
Guan et al. CaMKK2 regulates macrophage polarization induced by matrix stiffness: implications for shaping the immune response in stiffened tissues