JP2010515913A - マイクロ流体装置 - Google Patents

マイクロ流体装置 Download PDF

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Publication number
JP2010515913A
JP2010515913A JP2009545234A JP2009545234A JP2010515913A JP 2010515913 A JP2010515913 A JP 2010515913A JP 2009545234 A JP2009545234 A JP 2009545234A JP 2009545234 A JP2009545234 A JP 2009545234A JP 2010515913 A JP2010515913 A JP 2010515913A
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energization
microfluidic
teeth
chamber
layer
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JP2010515913A5 (https=
Inventor
ワマデヴァ バラチャンドラン，
サヤッド， モハマド アジミ，
ジェレミー アハーン，
マスード ゾルグハルニ，
モハマド レザ バーマンヤル，
プレドラグ スリジェプセヴィック，
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ブルーネル ユニバーシティ
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3032—Micromixers using magneto-hydrodynamic [MHD] phenomena to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Fluid Mechanics (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2009545234A 2007-01-12 2008-01-11 マイクロ流体装置 Withdrawn JP2010515913A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0700653A GB2446204A (en) 2007-01-12 2007-01-12 A Microfluidic device
PCT/GB2008/000094 WO2008084245A2 (en) 2007-01-12 2008-01-11 Microfluidic device

Publications (2)

Publication Number Publication Date
JP2010515913A true JP2010515913A (ja) 2010-05-13
JP2010515913A5 JP2010515913A5 (https=) 2011-03-03

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JP2009545234A Withdrawn JP2010515913A (ja) 2007-01-12 2008-01-11 マイクロ流体装置

Country Status (11)

Country Link
US (1) US20100216126A1 (https=)
EP (1) EP2117714A2 (https=)
JP (1) JP2010515913A (https=)
KR (1) KR20090104102A (https=)
CN (1) CN101631616A (https=)
AU (1) AU2008204364A1 (https=)
BR (1) BRPI0806582A2 (https=)
CA (1) CA2675079A1 (https=)
GB (1) GB2446204A (https=)
MX (1) MX2009007447A (https=)
WO (1) WO2008084245A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
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JP2018173414A (ja) * 2012-03-16 2018-11-08 スタット−ダイアグノスティカ アンド イノベーション， エス． エル． 統合された移送モジュールを有する試験カートリッジ
WO2021050723A1 (en) * 2019-09-10 2021-03-18 The Johns Hopkins University Device and method for genetic analysis of plant materials in remote testing sites
JP2023527790A (ja) * 2020-05-21 2023-06-30 バイオシンク・テクノロジーズ・ソシエダッド・リミターダ チップ上に統合されたラボラトリの製造方法
WO2023203925A1 (ja) * 2022-04-20 2023-10-26 株式会社日立ハイテク 自動分析装置

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DE102008003792A1 (de) * 2008-01-10 2009-07-16 Robert Bosch Gmbh Verfahren zum Herstellen einer Mikropumpe sowie Mikropumpe
GB0818609D0 (en) 2008-10-10 2008-11-19 Univ Hull apparatus and method
JP5550719B2 (ja) 2009-04-27 2014-07-16 イーアイ・スペクトラ・エルエルシー ピペット機器
EP2475459A1 (en) * 2009-09-11 2012-07-18 Koninklijke Philips Electronics N.V. Device and method for transporting magnetic or magnetisable beads
US20130018256A1 (en) * 2009-11-25 2013-01-17 Hanoch Kislev Probing system for measuring the direction and speed of mucus flow in vivo
JP5250574B2 (ja) * 2010-02-10 2013-07-31 富士フイルム株式会社 マイクロ流路デバイス
GB2483858A (en) * 2010-09-21 2012-03-28 Univ Hull Amplifying nucleic acids using microfluidic device to perform PRC
MY155579A (en) * 2010-09-28 2015-11-03 Mimos Berhad Micromixing device for miniturization for use in microfluidic applications
USD650090S1 (en) * 2011-01-18 2011-12-06 Zach Odeh Microfluidic device
CN102692515B (zh) * 2011-03-23 2014-09-17 成功大学 血液凝固测试用的生医晶片与其制造方法及用途
USD650911S1 (en) * 2011-04-19 2011-12-20 Zach Odeh Microfluidic device
USD650091S1 (en) * 2011-04-19 2011-12-06 Zach Odeh Microfluidic device
GB201109203D0 (en) * 2011-06-01 2011-07-13 Carclo Technical Plastics Ltd Fluid flow control
US9044729B2 (en) 2012-07-27 2015-06-02 International Park Of Creativity Methods and devices for electromagnetic amplification of nucleic acids
US10040018B2 (en) 2013-01-09 2018-08-07 Imagine Tf, Llc Fluid filters and methods of use
US9506934B2 (en) 2013-04-29 2016-11-29 Honeywell International Inc. Polymer test cartridge mixer for cell lysis
TW201445135A (zh) * 2013-05-23 2014-12-01 Nat Applied Res Laboratories 以複合電動力捕捉並分析生物微粒的方法與晶片
US9861920B1 (en) 2015-05-01 2018-01-09 Imagine Tf, Llc Three dimensional nanometer filters and methods of use
US10730047B2 (en) 2014-06-24 2020-08-04 Imagine Tf, Llc Micro-channel fluid filters and methods of use
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US10758849B2 (en) 2015-02-18 2020-09-01 Imagine Tf, Llc Three dimensional filter devices and apparatuses
CN104748656B (zh) * 2015-03-20 2018-06-26 江苏大学 基于巨磁阻的微流控磁珠位置检测方法与装置
US10118842B2 (en) 2015-07-09 2018-11-06 Imagine Tf, Llc Deionizing fluid filter devices and methods of use
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US10479046B2 (en) 2015-08-19 2019-11-19 Imagine Tf, Llc Absorbent microstructure arrays and methods of use
EP3347691B1 (de) * 2015-09-11 2022-01-12 Leibniz-Institut für Photonische Technologien e.V. Anordnung für die individualisierte patientenblutanalyse und verwendung
US10207266B2 (en) * 2015-09-29 2019-02-19 Foxconn Interconnect Technology Limited Microfluidic device for detecting cells of blood
US11033902B2 (en) * 2015-11-30 2021-06-15 Rqmicro Ag Microfluidic device, assemblies, and method for extracting particles from a sample
CN107344125A (zh) * 2016-05-05 2017-11-14 李榕生 流体驱动方式特异的廉价的艾滋病诊断用微流控装置
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CN106655703B (zh) * 2016-12-23 2019-04-16 上海大学 导电液体微量驱动装置及其应用
KR102344675B1 (ko) * 2017-04-21 2021-12-31 조에티스 서비시즈 엘엘씨 미세유체 분석용 시스템, 장치 및 방법
CN107384776A (zh) * 2017-08-04 2017-11-24 深圳市合川医疗科技有限公司 微流控芯片
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CN108536013B (zh) * 2018-03-29 2021-02-26 宁波大学 终端封闭微通道中粒子移动耦合模型控制方法
CN110433876B (zh) * 2018-05-03 2022-05-17 香港科技大学 微流控装置及其制造方法、口罩和过滤悬浮颗粒的方法
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USD951479S1 (en) * 2019-06-24 2022-05-10 Precision Nanosystems Inc. Microfluidic cartridge
CN111190022A (zh) * 2020-01-07 2020-05-22 中国科学院半导体研究所 基于谐振式传感器的生化检测系统及检测方法
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018173414A (ja) * 2012-03-16 2018-11-08 スタット−ダイアグノスティカ アンド イノベーション， エス． エル． 統合された移送モジュールを有する試験カートリッジ
WO2021050723A1 (en) * 2019-09-10 2021-03-18 The Johns Hopkins University Device and method for genetic analysis of plant materials in remote testing sites
JP2023527790A (ja) * 2020-05-21 2023-06-30 バイオシンク・テクノロジーズ・ソシエダッド・リミターダ チップ上に統合されたラボラトリの製造方法
WO2023203925A1 (ja) * 2022-04-20 2023-10-26 株式会社日立ハイテク 自動分析装置
JP2023159560A (ja) * 2022-04-20 2023-11-01 株式会社日立ハイテク 自動分析装置
JP7791768B2 (ja) 2022-04-20 2025-12-24 株式会社日立ハイテク 自動分析装置

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Publication number Publication date
KR20090104102A (ko) 2009-10-05
WO2008084245A3 (en) 2009-03-19
GB0700653D0 (en) 2007-02-21
AU2008204364A1 (en) 2008-07-17
BRPI0806582A2 (pt) 2014-05-06
US20100216126A1 (en) 2010-08-26
GB2446204A (en) 2008-08-06
WO2008084245A2 (en) 2008-07-17
MX2009007447A (es) 2010-03-01
CN101631616A (zh) 2010-01-20
EP2117714A2 (en) 2009-11-18
CA2675079A1 (en) 2008-07-17

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