JP2010515913A - マイクロ流体装置 - Google Patents

マイクロ流体装置 Download PDF

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Publication number
JP2010515913A
JP2010515913A JP2009545234A JP2009545234A JP2010515913A JP 2010515913 A JP2010515913 A JP 2010515913A JP 2009545234 A JP2009545234 A JP 2009545234A JP 2009545234 A JP2009545234 A JP 2009545234A JP 2010515913 A JP2010515913 A JP 2010515913A
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energization
microfluidic
teeth
chamber
layer
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JP2010515913A5 (enExample
Inventor
ワマデヴァ バラチャンドラン，
サヤッド， モハマド アジミ，
ジェレミー アハーン，
マスード ゾルグハルニ，
モハマド レザ バーマンヤル，
プレドラグ スリジェプセヴィック，
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ブルーネル ユニバーシティ
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3032—Micromixers using magneto-hydrodynamic [MHD] phenomena to mix or move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Fluid Mechanics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • Organic Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2009545234A 2007-01-12 2008-01-11 マイクロ流体装置 Withdrawn JP2010515913A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0700653A GB2446204A (en) 2007-01-12 2007-01-12 A Microfluidic device
PCT/GB2008/000094 WO2008084245A2 (en) 2007-01-12 2008-01-11 Microfluidic device

Publications (2)

Publication Number Publication Date
JP2010515913A true JP2010515913A (ja) 2010-05-13
JP2010515913A5 JP2010515913A5 (enExample) 2011-03-03

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JP2009545234A Withdrawn JP2010515913A (ja) 2007-01-12 2008-01-11 マイクロ流体装置

Country Status (11)

Country Link
US (1) US20100216126A1 (enExample)
EP (1) EP2117714A2 (enExample)
JP (1) JP2010515913A (enExample)
KR (1) KR20090104102A (enExample)
CN (1) CN101631616A (enExample)
AU (1) AU2008204364A1 (enExample)
BR (1) BRPI0806582A2 (enExample)
CA (1) CA2675079A1 (enExample)
GB (1) GB2446204A (enExample)
MX (1) MX2009007447A (enExample)
WO (1) WO2008084245A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
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JP2018173414A (ja) * 2012-03-16 2018-11-08 スタット−ダイアグノスティカ アンド イノベーション， エス． エル． 統合された移送モジュールを有する試験カートリッジ
WO2021050723A1 (en) * 2019-09-10 2021-03-18 The Johns Hopkins University Device and method for genetic analysis of plant materials in remote testing sites
JP2023527790A (ja) * 2020-05-21 2023-06-30 バイオシンク・テクノロジーズ・ソシエダッド・リミターダ チップ上に統合されたラボラトリの製造方法
WO2023203925A1 (ja) * 2022-04-20 2023-10-26 株式会社日立ハイテク 自動分析装置

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DE102008003792A1 (de) * 2008-01-10 2009-07-16 Robert Bosch Gmbh Verfahren zum Herstellen einer Mikropumpe sowie Mikropumpe
GB0818609D0 (en) 2008-10-10 2008-11-19 Univ Hull apparatus and method
CN102414550B (zh) 2009-04-27 2014-07-16 Ei频谱有限责任公司 移液器仪器
JP5711239B2 (ja) * 2009-09-11 2015-04-30 コーニンクレッカ フィリップス エヌ ヴェ 磁性ビーズ又は磁化可能なビーズを運搬する装置及び方法
US20130018256A1 (en) * 2009-11-25 2013-01-17 Hanoch Kislev Probing system for measuring the direction and speed of mucus flow in vivo
JP5250574B2 (ja) * 2010-02-10 2013-07-31 富士フイルム株式会社 マイクロ流路デバイス
GB2483858A (en) * 2010-09-21 2012-03-28 Univ Hull Amplifying nucleic acids using microfluidic device to perform PRC
MY155579A (en) * 2010-09-28 2015-11-03 Mimos Berhad Micromixing device for miniturization for use in microfluidic applications
USD650090S1 (en) * 2011-01-18 2011-12-06 Zach Odeh Microfluidic device
CN102692515B (zh) * 2011-03-23 2014-09-17 成功大学 血液凝固测试用的生医晶片与其制造方法及用途
USD650091S1 (en) * 2011-04-19 2011-12-06 Zach Odeh Microfluidic device
USD650911S1 (en) * 2011-04-19 2011-12-20 Zach Odeh Microfluidic device
GB201109203D0 (en) * 2011-06-01 2011-07-13 Carclo Technical Plastics Ltd Fluid flow control
US9044729B2 (en) 2012-07-27 2015-06-02 International Park Of Creativity Methods and devices for electromagnetic amplification of nucleic acids
US10040018B2 (en) 2013-01-09 2018-08-07 Imagine Tf, Llc Fluid filters and methods of use
US9506934B2 (en) 2013-04-29 2016-11-29 Honeywell International Inc. Polymer test cartridge mixer for cell lysis
TW201445135A (zh) * 2013-05-23 2014-12-01 Nat Applied Res Laboratories 以複合電動力捕捉並分析生物微粒的方法與晶片
US9861920B1 (en) 2015-05-01 2018-01-09 Imagine Tf, Llc Three dimensional nanometer filters and methods of use
US10730047B2 (en) 2014-06-24 2020-08-04 Imagine Tf, Llc Micro-channel fluid filters and methods of use
US10124275B2 (en) 2014-09-05 2018-11-13 Imagine Tf, Llc Microstructure separation filters
US10758849B2 (en) 2015-02-18 2020-09-01 Imagine Tf, Llc Three dimensional filter devices and apparatuses
CN104748656B (zh) * 2015-03-20 2018-06-26 江苏大学 基于巨磁阻的微流控磁珠位置检测方法与装置
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US10479046B2 (en) 2015-08-19 2019-11-19 Imagine Tf, Llc Absorbent microstructure arrays and methods of use
WO2017041782A1 (de) * 2015-09-11 2017-03-16 Leibniz-Institut Für Photonische Technologien E.V. Anordnung für die individualisierte patientenblutanalyse
US10207266B2 (en) * 2015-09-29 2019-02-19 Foxconn Interconnect Technology Limited Microfluidic device for detecting cells of blood
JP6570765B2 (ja) * 2015-11-30 2019-09-04 ルクミクロ アーゲーＲｑｍｉｃｒｏ Ａｇ 試料から粒子を抽出するためのマイクロ流体デバイス、アセンブリおよび方法
CN107344125A (zh) * 2016-05-05 2017-11-14 李榕生 流体驱动方式特异的廉价的艾滋病诊断用微流控装置
USD812242S1 (en) * 2016-07-13 2018-03-06 Precision Nanosystems Inc Microfluidic cartridge
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WO2018119401A2 (en) * 2016-12-22 2018-06-28 Daktari Diagnostics, Inc. Devices and methods for determining one or more analytes in fluids
CN106655703B (zh) * 2016-12-23 2019-04-16 上海大学 导电液体微量驱动装置及其应用
EP3612307A4 (en) * 2017-04-21 2021-06-09 Zoetis Services LLC SYSTEMS, DEVICES AND METHODS FOR MICROFLUIDIC ANALYSIS
CN107384776A (zh) * 2017-08-04 2017-11-24 深圳市合川医疗科技有限公司 微流控芯片
EP3697537A4 (en) 2017-10-18 2021-10-20 Group K Diagnostics, Inc. SINGLE-LAYER MICROFLUIDIC DEVICE AND ITS MANUFACTURING AND USE METHODS
CN108536013B (zh) * 2018-03-29 2021-02-26 宁波大学 终端封闭微通道中粒子移动耦合模型控制方法
CN110433876B (zh) * 2018-05-03 2022-05-17 香港科技大学 微流控装置及其制造方法、口罩和过滤悬浮颗粒的方法
USD879999S1 (en) 2018-11-02 2020-03-31 Group K Diagnostics, Inc. Microfluidic device
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KR102203994B1 (ko) * 2019-01-25 2021-01-18 한국기술교육대학교 산학협력단 감염원에 대한 항생제 감수성 검사용 유체 칩 및 이의 제조방법
USD951479S1 (en) * 2019-06-24 2022-05-10 Precision Nanosystems Inc. Microfluidic cartridge
CN111190022A (zh) * 2020-01-07 2020-05-22 中国科学院半导体研究所 基于谐振式传感器的生化检测系统及检测方法
USD989342S1 (en) * 2020-02-04 2023-06-13 Ut-Battelle, Llc Microfluidic polymer chip interface bracket
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USD1016324S1 (en) 2020-07-08 2024-02-27 NanoCav, LLC Biological cell processing chip
CN114100704B (zh) * 2020-09-22 2022-12-06 中国科学院深圳先进技术研究院 一种磁分选微流控芯片及其制作方法
WO2022165751A1 (zh) 2021-02-05 2022-08-11 京东方科技集团股份有限公司 微流控芯片
USD983405S1 (en) * 2021-04-15 2023-04-11 Cytoaurora Biotechnologies, Inc. Microfluidic chip
CN113522385B (zh) * 2021-07-14 2022-07-22 中新国际联合研究院 一种磁性数字微流体的移动结构及其自动化设备
CN113858540B (zh) * 2021-10-08 2023-07-28 佛山华智新材料有限公司 微流控芯片及其制造方法
CN117380112B (zh) * 2023-11-08 2026-06-26 中国科学院长春光学精密机械与物理研究所 三维微反应器的制作方法及三维微反应器

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018173414A (ja) * 2012-03-16 2018-11-08 スタット−ダイアグノスティカ アンド イノベーション， エス． エル． 統合された移送モジュールを有する試験カートリッジ
WO2021050723A1 (en) * 2019-09-10 2021-03-18 The Johns Hopkins University Device and method for genetic analysis of plant materials in remote testing sites
JP2023527790A (ja) * 2020-05-21 2023-06-30 バイオシンク・テクノロジーズ・ソシエダッド・リミターダ チップ上に統合されたラボラトリの製造方法
WO2023203925A1 (ja) * 2022-04-20 2023-10-26 株式会社日立ハイテク 自動分析装置
JP2023159560A (ja) * 2022-04-20 2023-11-01 株式会社日立ハイテク 自動分析装置
JP7791768B2 (ja) 2022-04-20 2025-12-24 株式会社日立ハイテク 自動分析装置

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Publication number Publication date
CA2675079A1 (en) 2008-07-17
CN101631616A (zh) 2010-01-20
EP2117714A2 (en) 2009-11-18
WO2008084245A3 (en) 2009-03-19
MX2009007447A (es) 2010-03-01
BRPI0806582A2 (pt) 2014-05-06
US20100216126A1 (en) 2010-08-26
AU2008204364A1 (en) 2008-07-17
WO2008084245A2 (en) 2008-07-17
GB0700653D0 (en) 2007-02-21
GB2446204A (en) 2008-08-06
KR20090104102A (ko) 2009-10-05

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