JP2010512747A5 - - Google Patents

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Publication number
JP2010512747A5
JP2010512747A5 JP2009541384A JP2009541384A JP2010512747A5 JP 2010512747 A5 JP2010512747 A5 JP 2010512747A5 JP 2009541384 A JP2009541384 A JP 2009541384A JP 2009541384 A JP2009541384 A JP 2009541384A JP 2010512747 A5 JP2010512747 A5 JP 2010512747A5
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JP
Japan
Prior art keywords
nucleic acid
acid molecule
isolated nucleic
seq
molecule according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009541384A
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English (en)
Japanese (ja)
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JP2010512747A (ja
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Publication date
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Priority claimed from PCT/US2007/025535 external-priority patent/WO2008076324A2/en
Publication of JP2010512747A publication Critical patent/JP2010512747A/ja
Publication of JP2010512747A5 publication Critical patent/JP2010512747A5/ja
Withdrawn legal-status Critical Current

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JP2009541384A 2006-12-14 2007-12-13 筋疾患および心臓血管障害を処置するための組成物および方法 Withdrawn JP2010512747A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86993706P 2006-12-14 2006-12-14
PCT/US2007/025535 WO2008076324A2 (en) 2006-12-14 2007-12-13 Compositions and methods to treat muscular & cardiovascular disorders

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2011178297A Division JP2012019789A (ja) 2006-12-14 2011-08-17 筋疾患および心臓血管障害を処置するための組成物および方法
JP2012034691A Division JP2012131812A (ja) 2006-12-14 2012-02-21 筋疾患および心臓血管障害を処置するための組成物および方法

Publications (2)

Publication Number Publication Date
JP2010512747A JP2010512747A (ja) 2010-04-30
JP2010512747A5 true JP2010512747A5 (https=) 2011-02-03

Family

ID=39536897

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2009541384A Withdrawn JP2010512747A (ja) 2006-12-14 2007-12-13 筋疾患および心臓血管障害を処置するための組成物および方法
JP2011178297A Withdrawn JP2012019789A (ja) 2006-12-14 2011-08-17 筋疾患および心臓血管障害を処置するための組成物および方法
JP2012034691A Withdrawn JP2012131812A (ja) 2006-12-14 2012-02-21 筋疾患および心臓血管障害を処置するための組成物および方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011178297A Withdrawn JP2012019789A (ja) 2006-12-14 2011-08-17 筋疾患および心臓血管障害を処置するための組成物および方法
JP2012034691A Withdrawn JP2012131812A (ja) 2006-12-14 2012-02-21 筋疾患および心臓血管障害を処置するための組成物および方法

Country Status (11)

Country Link
US (3) US20100280094A1 (https=)
EP (1) EP2104733A2 (https=)
JP (3) JP2010512747A (https=)
KR (1) KR20090098818A (https=)
CN (2) CN101563458A (https=)
AU (1) AU2007334502B2 (https=)
BR (1) BRPI0719995A2 (https=)
CA (1) CA2672606A1 (https=)
EA (2) EA200900782A1 (https=)
MX (1) MX2009006310A (https=)
WO (1) WO2008076324A2 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101485495B1 (ko) 2006-08-01 2015-01-22 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 베타-마이오신 중사슬의 발현을 활성화하는 마이크로-rna의 동정
WO2009018492A2 (en) 2007-07-31 2009-02-05 The Board Of Regents Of The University Of Texas System Micro-rnas that control myosin expression and myofiber identity
CN102356162A (zh) * 2009-02-04 2012-02-15 得克萨斯系统大学董事会 Mir-208和mir-499在治疗心脏病症中的双重靶向
IE20090047A1 (en) * 2009-02-26 2010-09-29 Nat Univ Ireland Protein targets in disease
US9034605B2 (en) 2009-03-12 2015-05-19 Brandeis University Reagents and methods for PCR
EA201370139A1 (ru) 2010-12-15 2013-10-30 Мираген Терапеутикс Ингибиторы микро-рнк, содержащие закрытые нуклеотиды
WO2013052965A2 (en) 2011-10-06 2013-04-11 Miragen Therapeutics Control of whole body energy homeostasis by microrna regulation
US9388408B2 (en) 2012-06-21 2016-07-12 MiRagen Therapeutics, Inc. Oligonucleotide-based inhibitors comprising locked nucleic acid motif
HK1212597A1 (zh) 2012-10-15 2016-06-17 Isis Pharmaceuticals, Inc. 用於調節c90rf72表達的組合物
WO2014062736A1 (en) 2012-10-15 2014-04-24 Isis Pharmaceuticals, Inc. Methods for monitoring c9orf72 expression
WO2014169126A1 (en) * 2013-04-10 2014-10-16 Reveragen Biopharma, Inc. Methods and agents to increase therapeutic dystrophin expression in muscle
EP4166667A3 (en) 2013-10-11 2023-08-02 Ionis Pharmaceuticals, Inc. Compositions for modulating c9orf72 expression
CN108064175A (zh) * 2014-08-04 2018-05-22 米拉根医疗股份有限公司 Myh7b的抑制剂及其用途
US9885042B2 (en) 2015-01-20 2018-02-06 MiRagen Therapeutics, Inc. miR-92 inhibitors and uses thereof
RS60230B1 (sr) 2015-04-16 2020-06-30 Ionis Pharmaceuticals Inc Kompozicije za moduliranje ekspresije c9orf72
US11260073B2 (en) 2015-11-02 2022-03-01 Ionis Pharmaceuticals, Inc. Compounds and methods for modulating C90RF72
CN106148519A (zh) * 2016-07-05 2016-11-23 无锡市第二人民医院 一种microRNA‑499的快速检测方法
WO2019014656A1 (en) 2017-07-14 2019-01-17 Han Si Ping METALLIC OLIGONUCLEOTIDE JONCTIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS
EP3665281A4 (en) * 2017-08-10 2021-05-05 City of Hope CONDITIONAL SIRNA AND ITS USE IN THE TREATMENT OF CARDIAC HYERTROPHY
KR102281710B1 (ko) 2021-02-19 2021-07-28 조기정 에어튜브를 이용한 선박 안전장치
CN119246849B (zh) * 2024-12-09 2025-03-14 上海基灵生物科技有限公司 一种检测犬心脏损伤的试剂盒及应用

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US5489677A (en) * 1990-07-27 1996-02-06 Isis Pharmaceuticals, Inc. Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
US5602240A (en) * 1990-07-27 1997-02-11 Ciba Geigy Ag. Backbone modified oligonucleotide analogs
ES2083593T3 (es) * 1990-08-03 1996-04-16 Sterling Winthrop Inc Compuestos y metodos para inhibir la expresion de genes.
US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
US5700922A (en) * 1991-12-24 1997-12-23 Isis Pharmaceuticals, Inc. PNA-DNA-PNA chimeric macromolecules
JP3516167B2 (ja) * 1992-12-08 2004-04-05 ローム株式会社 タンタルコンデンサチップの製造方法
US6271359B1 (en) * 1999-04-14 2001-08-07 Musc Foundation For Research Development Tissue-specific and pathogen-specific toxic agents and ribozymes
US20040259247A1 (en) * 2000-12-01 2004-12-23 Thomas Tuschl Rna interference mediating small rna molecules
ES2559828T3 (es) * 2003-07-16 2016-02-16 Protiva Biotherapeutics Inc. ARN de interferencia encapsulado en lípidos
US7521184B2 (en) * 2003-08-22 2009-04-21 Sirna Therapeutics, Inc. Detection and quantitation of nucleic acid molecules in biological samples
CA2566519C (en) * 2004-05-14 2020-04-21 Rosetta Genomics Ltd. Micrornas and uses thereof
WO2006107826A2 (en) * 2005-04-04 2006-10-12 The Board Of Regents Of The University Of Texas System Micro-rna's that regulate muscle cells
US20070092882A1 (en) * 2005-10-21 2007-04-26 Hui Wang Analysis of microRNA
EP1984497A2 (en) * 2006-01-10 2008-10-29 Koninklijke Nederlandse Akademie van Wetenschappen Nucleic acid molecules and collections thereof, their application and identification
KR101485495B1 (ko) * 2006-08-01 2015-01-22 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 베타-마이오신 중사슬의 발현을 활성화하는 마이크로-rna의 동정
WO2009018492A2 (en) * 2007-07-31 2009-02-05 The Board Of Regents Of The University Of Texas System Micro-rnas that control myosin expression and myofiber identity

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