JP2024500036A5 - - Google Patents
Info
- Publication number
- JP2024500036A5 JP2024500036A5 JP2023533634A JP2023533634A JP2024500036A5 JP 2024500036 A5 JP2024500036 A5 JP 2024500036A5 JP 2023533634 A JP2023533634 A JP 2023533634A JP 2023533634 A JP2023533634 A JP 2023533634A JP 2024500036 A5 JP2024500036 A5 JP 2024500036A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- double
- molecule
- stranded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2020534.0A GB202020534D0 (en) | 2020-12-23 | 2020-12-23 | Conjugate |
| GB2020534.0 | 2020-12-23 | ||
| PCT/EP2021/087570 WO2022136673A1 (en) | 2020-12-23 | 2021-12-23 | Conjugate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024500036A JP2024500036A (ja) | 2024-01-04 |
| JP2024500036A5 true JP2024500036A5 (https=) | 2024-12-26 |
Family
ID=74221032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023533634A Pending JP2024500036A (ja) | 2020-12-23 | 2021-12-23 | 抱合体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240352463A1 (https=) |
| EP (1) | EP4244357A1 (https=) |
| JP (1) | JP2024500036A (https=) |
| GB (2) | GB202020534D0 (https=) |
| WO (1) | WO2022136673A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250088573A (ko) * | 2022-10-14 | 2025-06-17 | 사네진 바이오 유에스에이 인크. | C3을 표적화하는 소형 간섭 rna 및 그의 용도 |
| WO2024169908A1 (zh) * | 2023-02-17 | 2024-08-22 | 苏州时安生物技术有限公司 | 一种调节补体C5表达的siRNA、其缀合物和药物组合物及用途 |
| WO2024187102A2 (en) * | 2023-03-09 | 2024-09-12 | Leal Therapeutics, Inc. | Compositions and methods for modulating c3 |
| WO2024189348A1 (en) * | 2023-03-14 | 2024-09-19 | Argonaute RNA Limited | Conjugate comprising a double stranded rna molecule linked to a single stranded dna molecule |
| WO2024228030A2 (en) * | 2023-05-04 | 2024-11-07 | Argonaute RNA Limited | Dual silencing |
| GB2629617B (en) * | 2023-05-04 | 2025-05-14 | Argonaute Rna Ltd | Dual Silencing |
| TW202516005A (zh) * | 2023-06-21 | 2025-04-16 | 美商翰森生物有限責任公司 | Ｓｉｒｎａ，含有ｓｉｒｎａ的綴合物，醫藥組成物及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2881743A1 (en) | 2002-09-25 | 2004-04-08 | University Of Massachusetts | In vivo gene silencing by chemically modified and stable sirna |
| EP2157182A3 (en) | 2005-03-08 | 2012-04-25 | Qiagen GmbH | Modified short interfering RNA |
| EP1891216B1 (en) * | 2005-05-25 | 2012-02-22 | The University Of York | Hybrid interfering rna |
| EP2845607A1 (en) | 2013-09-09 | 2015-03-11 | University of Vienna | Antisense oligonucleotides with improved pharmacokinetic properties |
| DK3569711T3 (da) * | 2014-12-15 | 2021-02-22 | Dicerna Pharmaceuticals Inc | Ligandmodificerede dobbeltstrengede nukleinsyrer |
| WO2016201301A1 (en) * | 2015-06-12 | 2016-12-15 | Alnylam Pharmaceuticals, Inc. | Complement component c5 irna compositions and methods of use thereof |
| AU2018232367A1 (en) * | 2017-03-09 | 2019-10-03 | Kyowa Kirin Co., Ltd. | Nucleic acid capable of inhibiting expression of MASP2 |
| WO2018185252A1 (en) * | 2017-04-05 | 2018-10-11 | Silence Therapeutics Gmbh | Nucleic acid conjugates |
| US20220017899A1 (en) * | 2018-11-23 | 2022-01-20 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of c3 in a cell |
| WO2021001646A2 (en) * | 2019-07-02 | 2021-01-07 | Argonaute RNA Limited | Apolipoprotein b antagonist |
| CN115066498A (zh) * | 2020-03-16 | 2022-09-16 | 阿尔戈诺特Rna有限公司 | Pcsk9的拮抗剂 |
-
2020
- 2020-12-23 GB GBGB2020534.0A patent/GB202020534D0/en not_active Ceased
-
2021
- 2021-12-23 US US18/268,769 patent/US20240352463A1/en active Pending
- 2021-12-23 GB GB2118938.6A patent/GB2604987A/en not_active Withdrawn
- 2021-12-23 JP JP2023533634A patent/JP2024500036A/ja active Pending
- 2021-12-23 EP EP21845035.1A patent/EP4244357A1/en not_active Withdrawn
- 2021-12-23 WO PCT/EP2021/087570 patent/WO2022136673A1/en not_active Ceased
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