JP2024500036A5 - - Google Patents

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Publication number
JP2024500036A5
JP2024500036A5 JP2023533634A JP2023533634A JP2024500036A5 JP 2024500036 A5 JP2024500036 A5 JP 2024500036A5 JP 2023533634 A JP2023533634 A JP 2023533634A JP 2023533634 A JP2023533634 A JP 2023533634A JP 2024500036 A5 JP2024500036 A5 JP 2024500036A5
Authority
JP
Japan
Application number
JP2023533634A
Other languages
Japanese (ja)
Other versions
JPWO2022136673A5 (https=
JP2024500036A (ja
Filing date
Publication date
Priority claimed from GBGB2020534.0A external-priority patent/GB202020534D0/en
Application filed filed Critical
Publication of JP2024500036A publication Critical patent/JP2024500036A/ja
Publication of JPWO2022136673A5 publication Critical patent/JPWO2022136673A5/ja
Publication of JP2024500036A5 publication Critical patent/JP2024500036A5/ja
Pending legal-status Critical Current

Links

JP2023533634A 2020-12-23 2021-12-23 抱合体 Pending JP2024500036A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2020534.0A GB202020534D0 (en) 2020-12-23 2020-12-23 Conjugate
GB2020534.0 2020-12-23
PCT/EP2021/087570 WO2022136673A1 (en) 2020-12-23 2021-12-23 Conjugate

Publications (3)

Publication Number Publication Date
JP2024500036A JP2024500036A (ja) 2024-01-04
JPWO2022136673A5 JPWO2022136673A5 (https=) 2024-12-26
JP2024500036A5 true JP2024500036A5 (https=) 2024-12-26

Family

ID=74221032

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023533634A Pending JP2024500036A (ja) 2020-12-23 2021-12-23 抱合体

Country Status (5)

Country Link
US (1) US20240352463A1 (https=)
EP (1) EP4244357A1 (https=)
JP (1) JP2024500036A (https=)
GB (2) GB202020534D0 (https=)
WO (1) WO2022136673A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120265773A (zh) * 2022-10-14 2025-07-04 美国圣因生物股份有限公司 靶向c3的小干扰rna及其用途
WO2024169908A1 (zh) * 2023-02-17 2024-08-22 苏州时安生物技术有限公司 一种调节补体C5表达的siRNA、其缀合物和药物组合物及用途
WO2024187102A2 (en) * 2023-03-09 2024-09-12 Leal Therapeutics, Inc. Compositions and methods for modulating c3
EP4680740A1 (en) * 2023-03-14 2026-01-21 Argonaute Rna Limited Conjugate comprising a double stranded rna molecule linked to a single stranded dna molecule
GB2629617B (en) * 2023-05-04 2025-05-14 Argonaute Rna Ltd Dual Silencing
WO2024228030A2 (en) * 2023-05-04 2024-11-07 Argonaute RNA Limited Dual silencing
AU2024312039A1 (en) * 2023-06-21 2026-01-22 Changzhou Hansoh Pharmaceutical Co., Ltd. Sirna, conjugate which contain sirna, pharmaceutical composition and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2500224C (en) 2002-09-25 2015-04-28 University Of Massachusetts In vivo gene silencing by chemically modified and stable sirna
EP1863912A2 (en) 2005-03-08 2007-12-12 Qiagen GmbH Modified short interfering rna
US8067572B2 (en) * 2005-05-25 2011-11-29 The University Of York Hybrid interfering RNA
EP2845607A1 (en) 2013-09-09 2015-03-11 University of Vienna Antisense oligonucleotides with improved pharmacokinetic properties
JP7105065B2 (ja) * 2014-12-15 2022-07-22 ダイセルナ ファーマシューティカルズ, インコーポレイテッド リガンド修飾二本鎖核酸
EP4365291A3 (en) * 2015-06-12 2024-08-14 Alnylam Pharmaceuticals, Inc. Complement component c5 irna compositions and methods of use thereof
JPWO2018164186A1 (ja) * 2017-03-09 2020-01-09 協和キリン株式会社 Masp2の発現を抑制する核酸
WO2018185252A1 (en) * 2017-04-05 2018-10-11 Silence Therapeutics Gmbh Nucleic acid conjugates
CA3119234A1 (en) * 2018-11-23 2020-05-28 Silence Therapeutics Gmbh Nucleic acids for inhibiting expression of c3 in a cell
US20230027604A1 (en) * 2019-07-02 2023-01-26 Argonaute RNA Limited Apolipoprotein b antagonist
US20230183694A1 (en) * 2020-03-16 2023-06-15 Argonaute RNA Limited Antagonist of pcsk9

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