JP2010512730A - 肺癌の腫瘍マーカーおよび治療標的としてのttk - Google Patents

肺癌の腫瘍マーカーおよび治療標的としてのttk Download PDF

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JP2010512730A
JP2010512730A JP2009524832A JP2009524832A JP2010512730A JP 2010512730 A JP2010512730 A JP 2010512730A JP 2009524832 A JP2009524832 A JP 2009524832A JP 2009524832 A JP2009524832 A JP 2009524832A JP 2010512730 A JP2010512730 A JP 2010512730A
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seq
ttk
polypeptide
egfr
amino acid
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JP2010512730A5 (enExample
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祐輔 中村
弥太郎 醍醐
修一 中鶴
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Oncotherapy Science Inc
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
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  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
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  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2009524832A 2006-12-13 2007-12-12 肺癌の腫瘍マーカーおよび治療標的としてのttk Withdrawn JP2010512730A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87479106P 2006-12-13 2006-12-13
PCT/JP2007/074359 WO2008072777A2 (en) 2006-12-13 2007-12-12 Ttk as tumor marker and therapeutic target for lung cancer

Publications (2)

Publication Number Publication Date
JP2010512730A true JP2010512730A (ja) 2010-04-30
JP2010512730A5 JP2010512730A5 (enExample) 2012-01-19

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JP2009524832A Withdrawn JP2010512730A (ja) 2006-12-13 2007-12-12 肺癌の腫瘍マーカーおよび治療標的としてのttk

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Country Link
US (1) US20100009920A1 (enExample)
EP (3) EP2468887A1 (enExample)
JP (1) JP2010512730A (enExample)
TW (1) TW200831673A (enExample)
WO (1) WO2008072777A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014501496A (ja) * 2010-10-20 2014-01-23 ユニヴェルシテ ボルドー セガラン 消化管間質腫瘍における臨床転帰のシグネチャーおよび消化管間質腫瘍の治療の方法
JP2016516669A (ja) * 2013-02-22 2016-06-09 ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 転写因子atf5の阻害により腫瘍細胞を阻害するための組成物および方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7847060B2 (en) * 2005-02-25 2010-12-07 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing TTK, URLC10 or KOC1 polypeptides
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
ES2339524B1 (es) * 2008-08-28 2011-03-22 Proyecto De Biomedicina Cima, S.L. Nuevo biomarcador como diana terapeutica en cancer de pulmon.
TW201102081A (en) 2009-05-11 2011-01-16 Oncotherapy Science Inc TTK peptides and vaccines including the same
EP2343294A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
WO2011130644A2 (en) * 2010-04-16 2011-10-20 Arqule, Inc. Phosphorylated nf45 biomarkers, antibodies and methods of using same
KR101232084B1 (ko) * 2011-10-31 2013-02-08 연세대학교 산학협력단 암 세포 바이오 마커를 동정하는 방법 및 상기 방법으로 동정한 nmd-무관 암 세포 바이오 마커
US10316077B2 (en) 2017-02-20 2019-06-11 Sapience Therapeutics, Inc. Cell-penetrating ATF5 polypeptides and uses thereof
CN109423517B (zh) * 2017-08-28 2022-08-05 中国医学科学院肿瘤医院 外泌体在肿瘤诊断、治疗和预后评估中的用途
JP6971508B2 (ja) 2018-01-03 2021-11-24 サピエンス・セラピューティクス・インコーポレーテッド Atf5ペプチド多様体及びそれらの使用

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US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
ES2294844T3 (es) 1998-06-25 2008-04-01 Green Peptide Co., Ltd. Peptidos antigenicos tumorales derivados de ciclofilina b.
US20020103360A1 (en) 1998-09-01 2002-08-01 Yang Pan Novel protein related to melanoma-inhibiting protein and uses thereof
US20030045491A1 (en) * 2001-02-23 2003-03-06 Christoph Reinhard TTK in diagnosis and as a therapeutic target in cancer
CN101732717A (zh) * 2001-02-21 2010-06-16 诺华疫苗和诊断公司 用于诊断和作为癌症治疗靶标的ttk
CA2467936C (en) 2001-11-21 2013-11-05 Mitsubishi Chemical Corporation Method of inhibiting gene expression
AU2003207708A1 (en) 2002-02-20 2003-09-09 Sirna Therapeutics, Inc. Rna interference mediated inhibition of map kinase genes
ATE513843T1 (de) 2002-09-25 2011-07-15 Univ Massachusetts Abstellen von genen in vivo durch chemischmodifizierte und stabile sirna
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20060024692A1 (en) * 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
DE602004015064D1 (de) * 2003-01-06 2008-08-28 Wyeth Corp Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs
WO2004070062A2 (en) * 2003-02-04 2004-08-19 Wyeth Compositions and methods for diagnosing and treating cancers
WO2005044976A2 (en) 2003-06-20 2005-05-19 Isis Pharmaceuticals, Inc. Oligomeric compounds for use in gene modulation
US20050136437A1 (en) 2003-08-25 2005-06-23 Nastech Pharmaceutical Company Inc. Nanoparticles for delivery of nucleic acids and stable double-stranded RNA
WO2005045037A2 (en) 2003-10-23 2005-05-19 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF 5-ALPHA REDUCTASE AND ANDROGEN RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2006021817A2 (en) 2004-08-23 2006-03-02 Sylentis S.A.U. Treatment of eye disorders characterized by an elevated introacular pressure by sirnas
EP2395109A1 (en) * 2004-12-08 2011-12-14 Aventis Pharmaceuticals Inc. Method for measuring resistance or sensitivity to docetaxel
EP2295601A1 (en) * 2005-02-10 2011-03-16 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
US7847060B2 (en) * 2005-02-25 2010-12-07 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing TTK, URLC10 or KOC1 polypeptides
US8053183B2 (en) * 2005-07-27 2011-11-08 Oncotherapy Science, Inc. Method of diagnosing esophageal cancer
TW201008574A (en) * 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014501496A (ja) * 2010-10-20 2014-01-23 ユニヴェルシテ ボルドー セガラン 消化管間質腫瘍における臨床転帰のシグネチャーおよび消化管間質腫瘍の治療の方法
JP2016516669A (ja) * 2013-02-22 2016-06-09 ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 転写因子atf5の阻害により腫瘍細胞を阻害するための組成物および方法
US10155796B2 (en) 2013-02-22 2018-12-18 The Trustees Of Columbia University In The City Of New York Compositions and methods for inhibiting tumor cells by inhibiting the transcription factor ATF5
US10273274B2 (en) 2013-02-22 2019-04-30 The Regents Of The University Of California Compositions and methods for inhibiting tumor cells by inhibiting the transcription factor ATF5
US11555057B2 (en) 2013-02-22 2023-01-17 The Trustees Of Columbia University In The City Of New York Compositions and methods for inhibiting tumor cells by inhibiting the transcription factor ATF5

Also Published As

Publication number Publication date
US20100009920A1 (en) 2010-01-14
EP2102360A2 (en) 2009-09-23
EP2468886A1 (en) 2012-06-27
EP2468887A1 (en) 2012-06-27
WO2008072777A2 (en) 2008-06-19
TW200831673A (en) 2008-08-01
WO2008072777A3 (en) 2008-07-31

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