JP2010511729A - ドライアイのための処置 - Google Patents

ドライアイのための処置 Download PDF

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Publication number
JP2010511729A
JP2010511729A JP2009540451A JP2009540451A JP2010511729A JP 2010511729 A JP2010511729 A JP 2010511729A JP 2009540451 A JP2009540451 A JP 2009540451A JP 2009540451 A JP2009540451 A JP 2009540451A JP 2010511729 A JP2010511729 A JP 2010511729A
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JP
Japan
Prior art keywords
composition
progestagen
pharmaceutically acceptable
concentration
acceptable carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2009540451A
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English (en)
Japanese (ja)
Other versions
JP2010511729A5 (enExample
Inventor
チャールズ ジー. コナー,
チャールズ ハイン,
Original Assignee
サザン カレッジ オブ オプトメトリー
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Application filed by サザン カレッジ オブ オプトメトリー filed Critical サザン カレッジ オブ オプトメトリー
Publication of JP2010511729A publication Critical patent/JP2010511729A/ja
Publication of JP2010511729A5 publication Critical patent/JP2010511729A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Eyeglasses (AREA)
JP2009540451A 2006-12-05 2007-12-05 ドライアイのための処置 Pending JP2010511729A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/634,347 US20080132475A1 (en) 2006-12-05 2006-12-05 Treatment for dry eye
PCT/US2007/086515 WO2008070726A2 (en) 2006-12-05 2007-12-05 Treatment for dry eye

Publications (2)

Publication Number Publication Date
JP2010511729A true JP2010511729A (ja) 2010-04-15
JP2010511729A5 JP2010511729A5 (enExample) 2012-01-05

Family

ID=39476533

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009540451A Pending JP2010511729A (ja) 2006-12-05 2007-12-05 ドライアイのための処置
JP2009540453A Pending JP2010511730A (ja) 2006-12-05 2007-12-05 テストステロンおよびプロゲスターゲンを用いたドライアイのための処置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009540453A Pending JP2010511730A (ja) 2006-12-05 2007-12-05 テストステロンおよびプロゲスターゲンを用いたドライアイのための処置

Country Status (12)

Country Link
US (3) US20080132475A1 (enExample)
EP (2) EP2101785A4 (enExample)
JP (2) JP2010511729A (enExample)
KR (2) KR20090104814A (enExample)
CN (2) CN101636164A (enExample)
AU (1) AU2009202711A1 (enExample)
BR (2) BRPI0719918A2 (enExample)
CA (2) CA2671769A1 (enExample)
EA (2) EA200900663A1 (enExample)
IL (1) IL199094A0 (enExample)
MX (2) MX2009005994A (enExample)
WO (2) WO2008070728A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015524434A (ja) * 2012-07-27 2015-08-24 ローズ テクノロジーズ 眼の疾病及び疾患のための組成物及び治療
JP2016513691A (ja) * 2013-03-15 2016-05-16 グリア エルエルシーGlia, Llc 医薬品の頭蓋部送達

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JP5894364B2 (ja) * 2007-08-16 2016-03-30 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド 眼および付属器組織の炎症を処置するための治療組成物
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen
US20110144077A1 (en) * 2008-08-05 2011-06-16 Thomas Cotter Treatment of retinal degeneration
WO2012103186A2 (en) * 2011-01-26 2012-08-02 Allergan, Inc. Androgen composition for treating an opthalmic condition
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
HRP20211377T1 (hr) 2011-11-23 2022-01-07 Therapeuticsmd, Inc. Prirodne kombinirane hormonske supstitucijske formulacije i terapije
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
KR20170005819A (ko) 2014-05-22 2017-01-16 쎄러퓨틱스엠디, 인코퍼레이티드 천연 복합 호르몬 대체 제형 및 요법
RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
EP4413974A3 (en) * 2014-10-20 2024-10-09 Oyster Point Pharma, Inc. Methods of treating ocular conditions
BR112017021044A2 (pt) * 2015-04-03 2018-07-24 Santen Pharmaceutical Co., Ltd. agente terapêutico para o olho seco compreendendo nandrolona ou éster da mesma ou metenolona ou éster da mesma como um ingrediente ativo
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
KR102630701B1 (ko) 2016-09-07 2024-01-29 글리아, 엘엘씨 두개 신경의 약리학적 피부 활성화에 의한 신경변성 질환과 관련된 증상의 치료
EP4057840A4 (en) * 2019-11-13 2023-11-15 Glia, LLC TESTOSTERONE COMPOSITIONS
WO2023107796A1 (en) * 2021-12-11 2023-06-15 The Regents Of The University Of California Ophthalmic formulations for macular degeneration

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WO1997020578A1 (en) * 1995-12-04 1997-06-12 University Of Miami Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance
US20030144635A1 (en) * 2002-01-30 2003-07-31 Connor Charles Gerald Method to use transdermal administration of androgens to the adnexa of the eye
WO2004045510A2 (en) * 2002-11-15 2004-06-03 Panaseca, Inc. Methods and compositions for alleviating dry eyes

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US20030144635A1 (en) * 2002-01-30 2003-07-31 Connor Charles Gerald Method to use transdermal administration of androgens to the adnexa of the eye
WO2004045510A2 (en) * 2002-11-15 2004-06-03 Panaseca, Inc. Methods and compositions for alleviating dry eyes

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015524434A (ja) * 2012-07-27 2015-08-24 ローズ テクノロジーズ 眼の疾病及び疾患のための組成物及び治療
JP2016513691A (ja) * 2013-03-15 2016-05-16 グリア エルエルシーGlia, Llc 医薬品の頭蓋部送達

Also Published As

Publication number Publication date
EP2124958A2 (en) 2009-12-02
BRPI0720172A2 (pt) 2014-01-07
EA200900663A1 (ru) 2009-12-30
MX2009005993A (es) 2009-12-14
KR20090104813A (ko) 2009-10-06
US20210008079A1 (en) 2021-01-14
CA2671698A1 (en) 2008-06-12
AU2009202711A1 (en) 2009-07-23
US20080132475A1 (en) 2008-06-05
CN101636165A (zh) 2010-01-27
US20140113889A1 (en) 2014-04-24
MX2009005994A (es) 2009-12-14
IL199094A0 (en) 2010-03-28
WO2008070728A3 (en) 2008-08-07
WO2008070728A2 (en) 2008-06-12
EP2101785A2 (en) 2009-09-23
WO2008070726A2 (en) 2008-06-12
EP2124958A4 (en) 2009-12-30
KR20090104814A (ko) 2009-10-06
WO2008070726A3 (en) 2008-08-21
EA200900662A1 (ru) 2009-12-30
BRPI0719918A2 (pt) 2014-03-04
EP2101785A4 (en) 2009-12-30
CA2671769A1 (en) 2008-06-12
CN101636164A (zh) 2010-01-27
JP2010511730A (ja) 2010-04-15

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