JP2010511706A5 - - Google Patents
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- Publication number
- JP2010511706A5 JP2010511706A5 JP2009540249A JP2009540249A JP2010511706A5 JP 2010511706 A5 JP2010511706 A5 JP 2010511706A5 JP 2009540249 A JP2009540249 A JP 2009540249A JP 2009540249 A JP2009540249 A JP 2009540249A JP 2010511706 A5 JP2010511706 A5 JP 2010511706A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence number
- compound
- amino acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000001875 compounds Chemical class 0.000 claims 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 235000018102 proteins Nutrition 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 230000026683 transduction Effects 0.000 claims 6
- 238000010361 transduction Methods 0.000 claims 6
- 208000030507 AIDS Diseases 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 4
- 235000001014 amino acid Nutrition 0.000 claims 3
- 229940024606 amino acid Drugs 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 208000011580 syndromic disease Diseases 0.000 claims 3
- 208000031886 HIV Infections Diseases 0.000 claims 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 claims 1
- 208000037357 HIV infectious disease Diseases 0.000 claims 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 1
- 101710201961 Virion infectivity factor Proteins 0.000 claims 1
- 229960001230 asparagine Drugs 0.000 claims 1
- 235000009582 asparagine Nutrition 0.000 claims 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 1
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 claims 1
- 230000029812 viral genome replication Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87318606P | 2006-12-06 | 2006-12-06 | |
| US60/873,186 | 2006-12-06 | ||
| PCT/US2007/024790 WO2008070049A2 (en) | 2006-12-06 | 2007-12-04 | Peptide and treatment for hiv-1 infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010511706A JP2010511706A (ja) | 2010-04-15 |
| JP2010511706A5 true JP2010511706A5 (enExample) | 2011-01-27 |
| JP5519291B2 JP5519291B2 (ja) | 2014-06-11 |
Family
ID=39492836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009540249A Expired - Fee Related JP5519291B2 (ja) | 2006-12-06 | 2007-12-04 | Ｈｉｖ−１感染症のためのペプチド及び治療法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8334255B2 (enExample) |
| EP (1) | EP2097090B1 (enExample) |
| JP (1) | JP5519291B2 (enExample) |
| AU (1) | AU2007328228B2 (enExample) |
| CA (1) | CA2671410C (enExample) |
| ES (1) | ES2526060T3 (enExample) |
| WO (1) | WO2008070049A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8778890B2 (en) | 2009-03-31 | 2014-07-15 | Temple University—Of the Commonwealth System of Higher Education | Leptin antagonist and methods of use |
| US10588902B2 (en) | 2013-06-24 | 2020-03-17 | Oyagen, Inc. | Camptothecin derivatives as anti-HIV agents and methods of identifying agents that disrupt Vif self-association |
| AU2017248353A1 (en) | 2016-04-07 | 2018-10-25 | Case Western Reserve University | TDP-43 mitochondrial localization inhibitor for the treatment of neurodegenerative disease |
| US11116762B2 (en) | 2017-01-04 | 2021-09-14 | Oyagen, Inc. | Compounds, compositions, and methods for treating human immunodeficiency virus |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0330359A3 (en) * | 1988-02-25 | 1991-06-05 | Bio-Rad Laboratories, Inc. | Composition useful in the diagnosis and treating of hiv-1 infection |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| US6653443B2 (en) | 2001-04-06 | 2003-11-25 | Thomas Jefferson University | Multimerization of HIV-1 Vif protein as a therapeutic target |
| CA2495478A1 (en) | 2002-08-05 | 2004-02-12 | University Of Rochester | Protein transducing domain/deaminase chimeric proteins, related compounds, and uses thereof |
| US7125849B2 (en) * | 2003-01-14 | 2006-10-24 | The Scripps Research Institute | Peptide-based angiogenesis inhibitors and methods of use thereof |
-
2007
- 2007-12-04 EP EP07862468.1A patent/EP2097090B1/en active Active
- 2007-12-04 US US12/448,058 patent/US8334255B2/en not_active Expired - Fee Related
- 2007-12-04 CA CA2671410A patent/CA2671410C/en not_active Expired - Fee Related
- 2007-12-04 AU AU2007328228A patent/AU2007328228B2/en not_active Ceased
- 2007-12-04 WO PCT/US2007/024790 patent/WO2008070049A2/en not_active Ceased
- 2007-12-04 ES ES07862468.1T patent/ES2526060T3/es active Active
- 2007-12-04 JP JP2009540249A patent/JP5519291B2/ja not_active Expired - Fee Related