CA2671410C - Peptide and treatment for hiv-1 infection - Google Patents

Peptide and treatment for hiv-1 infection Download PDF

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Publication number
CA2671410C
CA2671410C CA2671410A CA2671410A CA2671410C CA 2671410 C CA2671410 C CA 2671410C CA 2671410 A CA2671410 A CA 2671410A CA 2671410 A CA2671410 A CA 2671410A CA 2671410 C CA2671410 C CA 2671410C
Authority
CA
Canada
Prior art keywords
seq
arg
compound
ala
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2671410A
Other languages
English (en)
French (fr)
Other versions
CA2671410A1 (en
Inventor
Hui Zhang
Harold C. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
OYAGEN Inc
Original Assignee
Thomas Jefferson University
OYAGEN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University, OYAGEN Inc filed Critical Thomas Jefferson University
Publication of CA2671410A1 publication Critical patent/CA2671410A1/en
Application granted granted Critical
Publication of CA2671410C publication Critical patent/CA2671410C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2671410A 2006-12-06 2007-12-04 Peptide and treatment for hiv-1 infection Expired - Fee Related CA2671410C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87318606P 2006-12-06 2006-12-06
US60/873,186 2006-12-06
PCT/US2007/024790 WO2008070049A2 (en) 2006-12-06 2007-12-04 Peptide and treatment for hiv-1 infection

Publications (2)

Publication Number Publication Date
CA2671410A1 CA2671410A1 (en) 2008-06-12
CA2671410C true CA2671410C (en) 2016-11-22

Family

ID=39492836

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2671410A Expired - Fee Related CA2671410C (en) 2006-12-06 2007-12-04 Peptide and treatment for hiv-1 infection

Country Status (7)

Country Link
US (1) US8334255B2 (enExample)
EP (1) EP2097090B1 (enExample)
JP (1) JP5519291B2 (enExample)
AU (1) AU2007328228B2 (enExample)
CA (1) CA2671410C (enExample)
ES (1) ES2526060T3 (enExample)
WO (1) WO2008070049A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8778890B2 (en) 2009-03-31 2014-07-15 Temple University—Of the Commonwealth System of Higher Education Leptin antagonist and methods of use
US10588902B2 (en) 2013-06-24 2020-03-17 Oyagen, Inc. Camptothecin derivatives as anti-HIV agents and methods of identifying agents that disrupt Vif self-association
AU2017248353A1 (en) 2016-04-07 2018-10-25 Case Western Reserve University TDP-43 mitochondrial localization inhibitor for the treatment of neurodegenerative disease
US11116762B2 (en) 2017-01-04 2021-09-14 Oyagen, Inc. Compounds, compositions, and methods for treating human immunodeficiency virus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330359A3 (en) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Composition useful in the diagnosis and treating of hiv-1 infection
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
US6653443B2 (en) 2001-04-06 2003-11-25 Thomas Jefferson University Multimerization of HIV-1 Vif protein as a therapeutic target
CA2495478A1 (en) 2002-08-05 2004-02-12 University Of Rochester Protein transducing domain/deaminase chimeric proteins, related compounds, and uses thereof
US7125849B2 (en) * 2003-01-14 2006-10-24 The Scripps Research Institute Peptide-based angiogenesis inhibitors and methods of use thereof

Also Published As

Publication number Publication date
CA2671410A1 (en) 2008-06-12
ES2526060T3 (es) 2015-01-05
EP2097090A2 (en) 2009-09-09
EP2097090B1 (en) 2014-10-29
AU2007328228A1 (en) 2008-06-12
AU2007328228B2 (en) 2012-09-20
EP2097090A4 (en) 2012-07-11
WO2008070049A8 (en) 2008-10-30
JP2010511706A (ja) 2010-04-15
US20100029570A1 (en) 2010-02-04
WO2008070049A2 (en) 2008-06-12
JP5519291B2 (ja) 2014-06-11
US8334255B2 (en) 2012-12-18
WO2008070049A3 (en) 2009-01-29

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MKLA Lapsed

Effective date: 20171204