JP5519291B2 - Ｈｉｖ−１感染症のためのペプチド及び治療法 - Google Patents
Ｈｉｖ−１感染症のためのペプチド及び治療法 Download PDFInfo
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- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 229960002898 threonine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 239000003104 tissue culture media Substances 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000440 toxicity profile Toxicity 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 108091008023 transcriptional regulators Proteins 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
- 229940035722 triiodothyronine Drugs 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 229960004799 tryptophan Drugs 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
- 229960004295 valine Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 210000005048 vimentin Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87318606P | 2006-12-06 | 2006-12-06 | |
| US60/873,186 | 2006-12-06 | ||
| PCT/US2007/024790 WO2008070049A2 (en) | 2006-12-06 | 2007-12-04 | Peptide and treatment for hiv-1 infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010511706A JP2010511706A (ja) | 2010-04-15 |
| JP2010511706A5 JP2010511706A5 (enExample) | 2011-01-27 |
| JP5519291B2 true JP5519291B2 (ja) | 2014-06-11 |
Family
ID=39492836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009540249A Expired - Fee Related JP5519291B2 (ja) | 2006-12-06 | 2007-12-04 | Ｈｉｖ−１感染症のためのペプチド及び治療法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8334255B2 (enExample) |
| EP (1) | EP2097090B1 (enExample) |
| JP (1) | JP5519291B2 (enExample) |
| AU (1) | AU2007328228B2 (enExample) |
| CA (1) | CA2671410C (enExample) |
| ES (1) | ES2526060T3 (enExample) |
| WO (1) | WO2008070049A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8778890B2 (en) | 2009-03-31 | 2014-07-15 | Temple University—Of the Commonwealth System of Higher Education | Leptin antagonist and methods of use |
| US10588902B2 (en) | 2013-06-24 | 2020-03-17 | Oyagen, Inc. | Camptothecin derivatives as anti-HIV agents and methods of identifying agents that disrupt Vif self-association |
| AU2017248353A1 (en) | 2016-04-07 | 2018-10-25 | Case Western Reserve University | TDP-43 mitochondrial localization inhibitor for the treatment of neurodegenerative disease |
| US11116762B2 (en) | 2017-01-04 | 2021-09-14 | Oyagen, Inc. | Compounds, compositions, and methods for treating human immunodeficiency virus |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0330359A3 (en) * | 1988-02-25 | 1991-06-05 | Bio-Rad Laboratories, Inc. | Composition useful in the diagnosis and treating of hiv-1 infection |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| US6653443B2 (en) | 2001-04-06 | 2003-11-25 | Thomas Jefferson University | Multimerization of HIV-1 Vif protein as a therapeutic target |
| CA2495478A1 (en) | 2002-08-05 | 2004-02-12 | University Of Rochester | Protein transducing domain/deaminase chimeric proteins, related compounds, and uses thereof |
| US7125849B2 (en) * | 2003-01-14 | 2006-10-24 | The Scripps Research Institute | Peptide-based angiogenesis inhibitors and methods of use thereof |
-
2007
- 2007-12-04 EP EP07862468.1A patent/EP2097090B1/en active Active
- 2007-12-04 US US12/448,058 patent/US8334255B2/en not_active Expired - Fee Related
- 2007-12-04 CA CA2671410A patent/CA2671410C/en not_active Expired - Fee Related
- 2007-12-04 AU AU2007328228A patent/AU2007328228B2/en not_active Ceased
- 2007-12-04 WO PCT/US2007/024790 patent/WO2008070049A2/en not_active Ceased
- 2007-12-04 ES ES07862468.1T patent/ES2526060T3/es active Active
- 2007-12-04 JP JP2009540249A patent/JP5519291B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2671410A1 (en) | 2008-06-12 |
| ES2526060T3 (es) | 2015-01-05 |
| EP2097090A2 (en) | 2009-09-09 |
| EP2097090B1 (en) | 2014-10-29 |
| AU2007328228A1 (en) | 2008-06-12 |
| AU2007328228B2 (en) | 2012-09-20 |
| CA2671410C (en) | 2016-11-22 |
| EP2097090A4 (en) | 2012-07-11 |
| WO2008070049A8 (en) | 2008-10-30 |
| JP2010511706A (ja) | 2010-04-15 |
| US20100029570A1 (en) | 2010-02-04 |
| WO2008070049A2 (en) | 2008-06-12 |
| US8334255B2 (en) | 2012-12-18 |
| WO2008070049A3 (en) | 2009-01-29 |
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