JP2010511694A5 - - Google Patents

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Publication number
JP2010511694A5
JP2010511694A5 JP2009539869A JP2009539869A JP2010511694A5 JP 2010511694 A5 JP2010511694 A5 JP 2010511694A5 JP 2009539869 A JP2009539869 A JP 2009539869A JP 2009539869 A JP2009539869 A JP 2009539869A JP 2010511694 A5 JP2010511694 A5 JP 2010511694A5
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JP
Japan
Prior art keywords
halogen
growth factor
receptor
factor receptor
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009539869A
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English (en)
Japanese (ja)
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JP2010511694A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IL2007/001494 external-priority patent/WO2008068751A1/en
Publication of JP2010511694A publication Critical patent/JP2010511694A/ja
Publication of JP2010511694A5 publication Critical patent/JP2010511694A5/ja
Pending legal-status Critical Current

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JP2009539869A 2006-12-04 2007-12-04 新規なタンパク質キナーゼ修飾因子および治療におけるその使用 Pending JP2010511694A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87251106P 2006-12-04 2006-12-04
PCT/IL2007/001494 WO2008068751A1 (en) 2006-12-04 2007-12-04 Novel protein kinase modulators and therapeutic uses thereof

Publications (2)

Publication Number Publication Date
JP2010511694A JP2010511694A (ja) 2010-04-15
JP2010511694A5 true JP2010511694A5 (https=) 2012-02-02

Family

ID=39111493

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009539869A Pending JP2010511694A (ja) 2006-12-04 2007-12-04 新規なタンパク質キナーゼ修飾因子および治療におけるその使用

Country Status (8)

Country Link
US (1) US8058309B2 (https=)
EP (1) EP2125712B1 (https=)
JP (1) JP2010511694A (https=)
CN (1) CN101652345A (https=)
AU (1) AU2007330333A1 (https=)
BR (1) BRPI0719708A2 (https=)
CA (1) CA2671632A1 (https=)
WO (1) WO2008068751A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2758016A1 (en) * 2008-06-05 2009-12-10 Novotyr Therapeutics Ltd. Novel modulators of protein kinase signaling
ES2566673T3 (es) 2010-12-27 2016-04-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Derivados 2-(2-feniletenilo)-1,3-benzotiazol útiles para el tratamiento del cáncer
WO2012117396A1 (en) 2011-03-01 2012-09-07 Novotyr Therapeutics Ltd Tyrphostin derivative in combination with cytotoxic compounds for treating cancer
EP3021944B1 (en) * 2013-07-14 2018-12-19 Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. Igf-1r signaling pathway inhibitors useful in the treatment of neurodegenerative diseases
CN107250108B (zh) * 2015-02-05 2020-11-27 特尔诺沃有限公司 用于治疗癌症的irs/stat3双重调节剂与抗癌剂的组合
WO2019097503A1 (en) 2017-11-16 2019-05-23 Tyrnovo Ltd. Combinations of irs/stat3 dual modulators and anti pd-1/pd-l1 antibodies for treating cancer
WO2019246273A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor
CN115466205B (zh) * 2021-11-04 2023-10-24 特尔诺沃有限公司 分离的3-(2-溴-3,4-二羟基-苯基)-n-(3,4,5-三羟基-苄基)-硫代丙烯酰胺的反式异构体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217999A (en) 1987-12-24 1993-06-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Styryl compounds which inhibit EGF receptor protein tyrosine kinase
WO1995024190A2 (en) * 1994-03-07 1995-09-14 Sugen, Inc. Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
US20040197335A1 (en) * 2001-06-14 2004-10-07 Shimon Slavin Non-myeloablative tolerogenic treatment with tyrphostins
CA2466928A1 (en) * 2001-12-10 2003-07-03 Yansheng Du Treatment of neurodegenerative and cardiovascular disorders
WO2003101927A1 (en) * 2002-05-31 2003-12-11 Proteotech, Inc. Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease

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