JP2010509369A5 - - Google Patents
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- Publication number
- JP2010509369A5 JP2010509369A5 JP2009536520A JP2009536520A JP2010509369A5 JP 2010509369 A5 JP2010509369 A5 JP 2010509369A5 JP 2009536520 A JP2009536520 A JP 2009536520A JP 2009536520 A JP2009536520 A JP 2009536520A JP 2010509369 A5 JP2010509369 A5 JP 2010509369A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- vegf
- antibody
- use according
- average thickness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000005557 antagonist Substances 0.000 claims description 17
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims description 16
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims description 16
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims description 12
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims description 12
- 208000000208 Wet Macular Degeneration Diseases 0.000 claims description 4
- 206010064930 age-related macular degeneration Diseases 0.000 claims description 4
- 208000002780 macular degeneration Diseases 0.000 claims description 4
- 238000005259 measurement Methods 0.000 claims description 4
- 238000002560 therapeutic procedure Methods 0.000 claims description 4
- 229960003876 ranibizumab Drugs 0.000 claims description 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 description 14
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86538006P | 2006-11-10 | 2006-11-10 | |
| PCT/US2007/084320 WO2008063932A2 (en) | 2006-11-10 | 2007-11-09 | Method for treating age-related macular degeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010509369A JP2010509369A (ja) | 2010-03-25 |
| JP2010509369A5 true JP2010509369A5 (enExample) | 2010-12-02 |
Family
ID=39323041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009536520A Pending JP2010509369A (ja) | 2006-11-10 | 2007-11-09 | 加齢黄斑変性症を処置するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20100111963A1 (enExample) |
| EP (1) | EP2089059A2 (enExample) |
| JP (1) | JP2010509369A (enExample) |
| AU (1) | AU2007323925A1 (enExample) |
| CA (1) | CA2666709A1 (enExample) |
| WO (1) | WO2008063932A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS52539B (sr) * | 2004-10-21 | 2013-04-30 | Genentech Inc. | Metod za tretiranje intraokularnih neovaskularnih bolesti |
| RU2653753C1 (ru) | 2008-06-25 | 2018-05-14 | ИЭсБиЭйТЕК, ЭН АЛЬКОН БАЙОМЕДИКАЛ РИСЕРЧ ЮНИТ ЭлЭлСи | СТАБИЛЬНЫЕ И РАСТВОРИМЫЕ АНТИТЕЛА, ИНГИБИРУЮЩИЕ TNFα |
| HUE032894T2 (hu) | 2008-06-25 | 2017-11-28 | Esbatech Alcon Biomed Res Unit | VEGF-gátló, stabilis és oldható antitestek |
| AU2009269149B2 (en) * | 2008-06-30 | 2016-03-17 | Mesoblast, Inc. | Treatment of eye diseases and excessive neovascularization using a combined therapy |
| US8821870B2 (en) * | 2008-07-18 | 2014-09-02 | Allergan, Inc. | Method for treating atrophic age related macular degeneration |
| JP5606438B2 (ja) | 2008-07-23 | 2014-10-15 | エフ.ホフマン−ラ ロシュ アーゲー | 抗血管新生療法を受容可能な被験体の同定 |
| AU2011206104A1 (en) * | 2010-01-14 | 2012-07-12 | Nagoya City University | Pharmaceutical for preventing or treating disorders accompanied by ocular angiogenesis and/or elevated ocular vascular permeability |
| AR083495A1 (es) | 2010-10-22 | 2013-02-27 | Esbatech Alcon Biomed Res Unit | Anticuerpos estables y solubles |
| EA022873B1 (ru) * | 2010-10-27 | 2016-03-31 | Новартис Аг | Применение ингибитора vegf-r2 для лечения офтальмологического сосудистого заболевания |
| KR20200077622A (ko) | 2011-01-13 | 2020-06-30 | 리제너론 파아마슈티컬스, 인크. | 혈관신생 눈 장애를 치료하기 위한 vegf 길항제의 용도 |
| EP2671589A4 (en) * | 2011-02-02 | 2014-11-19 | Public Univ Corp Nagoya City Univ | MEDICAMENT FOR PREVENTING OR TREATING DISEASES RELATED TO INTRAOCULAR NEOVASCULARIZATION AND / OR INTRAOCULAR VASCULAR HYPERPERMEABILITY |
| WO2014031429A2 (en) * | 2012-08-21 | 2014-02-27 | Opko Pharmaceuticals, Llc | Liposome formulations |
| US11458199B2 (en) * | 2012-08-21 | 2022-10-04 | Opko Pharmaceuticals, Llc | Liposome formulations |
| AU2014274703B2 (en) * | 2013-06-07 | 2019-07-04 | The Johns Hopkins University | A biomimetic peptide and biodegradable delivery platform for the treatment of angiogenesis- and lymphangiogenesis-dependent diseases |
| HK1220144A1 (zh) * | 2013-10-08 | 2017-04-28 | 豪夫迈‧罗氏有限公司 | N-(4-叔丁基-苄基)-3-氯-n-[2-(4-氯-3-乙基-苯基)-乙基]-2-氟-5-三氟甲基-苯甲酰胺用於治疗眼疾病的用途 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| US20180280414A1 (en) * | 2015-10-13 | 2018-10-04 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of choroidal neovascularisation |
| KR101880670B1 (ko) * | 2015-11-06 | 2018-08-16 | 주식회사 모다이노칩 | 압력 센서를 구비하는 전자기기 |
| CN114712497B (zh) | 2015-12-03 | 2024-03-22 | 雷杰纳荣制药公司 | 抗vegf剂在制备用于治疗新生血管性年龄相关性黄斑变性患者的药物中的用途 |
| BR112018013407A2 (en) | 2015-12-30 | 2018-12-18 | Kodiak Sciences Inc. | antibodies and conjugates thereof |
| WO2018051312A1 (en) * | 2016-09-19 | 2018-03-22 | Lupin Limited | In-line filter for protein/peptide drug administration |
| IL274711B2 (en) | 2017-11-30 | 2024-10-01 | Regeneron Pharma | Use of a vegf antagonist to treat angiogenic eye disorders |
| SG11202006255UA (en) | 2018-02-02 | 2020-07-29 | Univ Kyoto | Medicine for preventing or treating ophthalmic disease associated with enhanced intraocular neovascularization and/or intraocular vascular permeability |
| SG11202008242XA (en) | 2018-03-02 | 2020-09-29 | Kodiak Sciences Inc | Il-6 antibodies and fusion constructs and conjugates thereof |
| US11519020B2 (en) | 2018-05-25 | 2022-12-06 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
| WO2020109343A1 (en) | 2018-11-29 | 2020-06-04 | F. Hoffmann-La Roche Ag | Combination therapy for treatment of macular degeneration |
| KR20250051157A (ko) | 2019-06-05 | 2025-04-16 | 리제너론 파아마슈티컬스, 인크. | 정밀 투여량 전달을 위한 디바이스 및 방법 |
| US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US190317A (en) * | 1877-05-01 | Improvement in barbers chairs | ||
| US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| US6703020B1 (en) * | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| US7306799B2 (en) * | 1999-06-08 | 2007-12-11 | Regeneron Pharmaceuticals, Inc. | Use of VEGF inhibitors for treatment of eye disorders |
| WO2003068801A2 (en) * | 2002-02-11 | 2003-08-21 | Genentech, Inc. | Antibody variants with faster antigen association rates |
-
2007
- 2007-11-09 WO PCT/US2007/084320 patent/WO2008063932A2/en not_active Ceased
- 2007-11-09 EP EP07871431A patent/EP2089059A2/en not_active Withdrawn
- 2007-11-09 US US12/514,445 patent/US20100111963A1/en not_active Abandoned
- 2007-11-09 JP JP2009536520A patent/JP2010509369A/ja active Pending
- 2007-11-09 CA CA002666709A patent/CA2666709A1/en not_active Abandoned
- 2007-11-09 AU AU2007323925A patent/AU2007323925A1/en not_active Abandoned
-
2011
- 2011-09-19 US US13/236,515 patent/US20120009185A1/en not_active Abandoned
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