JP2010509369A - 加齢黄斑変性症を処置するための方法 - Google Patents
加齢黄斑変性症を処置するための方法 Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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| PCT/US2007/084320 WO2008063932A2 (en) | 2006-11-10 | 2007-11-09 | Method for treating age-related macular degeneration |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012105610A1 (ja) * | 2011-02-02 | 2012-08-09 | 公立大学法人名古屋市立大学 | 眼内血管新生及び／又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬 |
| JP2014503555A (ja) * | 2011-01-13 | 2014-02-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2016521712A (ja) * | 2013-06-07 | 2016-07-25 | ザ ジョンズ ホプキンス ユニバーシティ | 血管新生およびリンパ管新生依存性疾患の処置のための生体模倣ペプチドおよび生分解性送達プラットフォーム |
| JP2016532658A (ja) * | 2013-10-08 | 2016-10-20 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 眼病の処置のためのＮ−（４−ｔｅｒｔ−ブチルベンジル）−３−クロロ−Ｎ−［２−（４−クロロ−３−エチル−フェニル）−エチル］−２−フルオロ−５−トリフルオロメチル−ベンズアミドの使用 |
| US11519020B2 (en) | 2018-05-25 | 2022-12-06 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
| US11769597B2 (en) | 2015-12-03 | 2023-09-26 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
| US12280093B2 (en) | 2017-11-30 | 2025-04-22 | Regenron Pharmaceuticals, Inc. | Use of a VEGF receptor-based fusion protein antagonist to treat nonproliferative diabetic retinopathy |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005299701B2 (en) * | 2004-10-21 | 2011-11-17 | Genentech, Inc. | Method for treating intraocular neovascular diseases |
| KR101737466B1 (ko) | 2008-06-25 | 2017-05-18 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | Ｖｅｇｆ를 억제하는 안정하고 가용성인 항체 |
| WO2009155723A2 (en) | 2008-06-25 | 2009-12-30 | Esbatech, An Alcon Biomedical Research Unit Llc | STABLE AND SOLUBLE ANTIBODIES INHIBITING TNFα |
| SG10201510586PA (en) * | 2008-06-30 | 2016-01-28 | Mesoblast Inc | Treatment of Eye Diseases And Excessive Neovascularization Using A Combined Therapy |
| US8821870B2 (en) * | 2008-07-18 | 2014-09-02 | Allergan, Inc. | Method for treating atrophic age related macular degeneration |
| WO2010010153A1 (en) | 2008-07-23 | 2010-01-28 | F. Hoffmann-La Roche Ag | Identification of subjects being susceptible to anti-angiogenesis therapy |
| CN102711756A (zh) * | 2010-01-14 | 2012-10-03 | 株式会社三和化学研究所 | 用于预防或治疗伴有眼内血管生成及/或眼内血管通透性增高的疾病的药物 |
| UY33679A (es) | 2010-10-22 | 2012-03-30 | Esbatech | Anticuerpos estables y solubles |
| CA2814439A1 (en) * | 2010-10-27 | 2012-05-03 | Novartis Ag | Dosing regimes for the treatment of ocular vascular disease |
| US11458199B2 (en) * | 2012-08-21 | 2022-10-04 | Opko Pharmaceuticals, Llc | Liposome formulations |
| US10548841B2 (en) * | 2012-08-21 | 2020-02-04 | Opko Pharmaceuticals, Llc | Liposome formulations |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| EP3362095B1 (en) * | 2015-10-13 | 2020-11-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of choroidal neovascularisation |
| KR101880670B1 (ko) * | 2015-11-06 | 2018-08-16 | 주식회사 모다이노칩 | 압력 센서를 구비하는 전자기기 |
| CA3010056A1 (en) | 2015-12-30 | 2017-07-06 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| EP3515536A1 (en) * | 2016-09-19 | 2019-07-31 | Lupin Limited | In-line filter for protein/peptide drug administration |
| JPWO2019151470A1 (ja) | 2018-02-02 | 2021-02-25 | 国立大学法人京都大学 | 眼内血管新生及び／又は眼内血管透過性亢進を伴う眼科疾患の予防又は治療のための医薬 |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| WO2020109343A1 (en) | 2018-11-29 | 2020-06-04 | F. Hoffmann-La Roche Ag | Combination therapy for treatment of macular degeneration |
| CN114786731A (zh) | 2019-10-10 | 2022-07-22 | 科达制药股份有限公司 | 治疗眼部病症的方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US190317A (en) * | 1877-05-01 | Improvement in barbers chairs | ||
| US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| US6703020B1 (en) * | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| US7306799B2 (en) * | 1999-06-08 | 2007-12-11 | Regeneron Pharmaceuticals, Inc. | Use of VEGF inhibitors for treatment of eye disorders |
| BR0307548A (pt) * | 2002-02-11 | 2006-01-17 | Genentech Inc | Método de produção de uma variante de anticorpo, variante de anticorpo, composição, ácido nucléico isolado, vetor, célula hospedeira, processo para a produção de uma variante de anticorpo e método de determinação do coeficiente de associação de antìgeno de um anticorpo |
-
2007
- 2007-11-09 JP JP2009536520A patent/JP2010509369A/ja active Pending
- 2007-11-09 CA CA002666709A patent/CA2666709A1/en not_active Abandoned
- 2007-11-09 US US12/514,445 patent/US20100111963A1/en not_active Abandoned
- 2007-11-09 AU AU2007323925A patent/AU2007323925A1/en not_active Abandoned
- 2007-11-09 WO PCT/US2007/084320 patent/WO2008063932A2/en not_active Ceased
- 2007-11-09 EP EP07871431A patent/EP2089059A2/en not_active Withdrawn
-
2011
- 2011-09-19 US US13/236,515 patent/US20120009185A1/en not_active Abandoned
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| JPN5010000495; ＨＥＩＥＲ Ｊ Ｓ: ＩＯＶＳ Ｖ４６ Ｎ．ＳＵＰＰＬ．Ｓ, 2005, ＡＢＳＴＲＡＣＴ １３９３ * |
| JPN5010000496; ［ＯＮＬＩＮＥ］ , 20060603 * |
| JPN5010000498; ＲＯＳＥＮＦＥＬＤ Ｐ: ＲＥＶＩＥＷ ＯＦ ＯＰＨＴＨＡＬＭＯＬＯＧＹ ［ＯＮＬＩＮＥ］ Ｖ１２ Ｎ１２, 20051201 * |
| JPN6012064424; ＬＵＣＥＮＴＩＳ Ｐｒｅｓｃｒｉｂｉｎｇ Ｉｎｆｏｒｍａｔｉｏｎ - Ｇｅｎｅｎｔｅｃｈ , 200610 * |
| JPN6012064426; 臨床眼科， Ｖｏｌ．５８ Ｎｏ．７， ｐ．１２６５-３９ （２００４） * |
| JPN6012064428; 臨床眼科， Ｖｏｌ．６０ Ｎｏ．４， ｐ．５７７-８０ （２００６ Ａｐｒ） * |
| JPN6012064430; 眼科， Ｖｏｌ．４２， ｐ．８８７-８９３ （２０００） * |
| JPN6012064432; Ｂｒ Ｊ Ｏｐｈｔｈａｌｍｏｌ．， Ｖｏｌ．８９ ｐ．３１６-２０ （２００５） * |
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| US11253572B2 (en) | 2011-01-13 | 2022-02-22 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US9254338B2 (en) | 2011-01-13 | 2016-02-09 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US12268730B2 (en) | 2011-01-13 | 2025-04-08 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US11986511B2 (en) | 2011-01-13 | 2024-05-21 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| JP2017061467A (ja) * | 2011-01-13 | 2017-03-30 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| US9669069B2 (en) | 2011-01-13 | 2017-06-06 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US10130681B2 (en) | 2011-01-13 | 2018-11-20 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US10828345B2 (en) | 2011-01-13 | 2020-11-10 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US11975045B2 (en) | 2011-01-13 | 2024-05-07 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| JP2014503555A (ja) * | 2011-01-13 | 2014-02-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| US11730794B2 (en) | 2011-01-13 | 2023-08-22 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US10857205B2 (en) | 2011-01-13 | 2020-12-08 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US11559564B2 (en) | 2011-01-13 | 2023-01-24 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US11707506B2 (en) | 2011-01-13 | 2023-07-25 | Regeneren Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| WO2012105610A1 (ja) * | 2011-02-02 | 2012-08-09 | 公立大学法人名古屋市立大学 | 眼内血管新生及び／又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬 |
| JP2016521712A (ja) * | 2013-06-07 | 2016-07-25 | ザ ジョンズ ホプキンス ユニバーシティ | 血管新生およびリンパ管新生依存性疾患の処置のための生体模倣ペプチドおよび生分解性送達プラットフォーム |
| JP2016532658A (ja) * | 2013-10-08 | 2016-10-20 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 眼病の処置のためのＮ−（４−ｔｅｒｔ−ブチルベンジル）−３−クロロ−Ｎ−［２−（４−クロロ−３−エチル−フェニル）−エチル］−２−フルオロ−５−トリフルオロメチル−ベンズアミドの使用 |
| US11769597B2 (en) | 2015-12-03 | 2023-09-26 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
| US12280093B2 (en) | 2017-11-30 | 2025-04-22 | Regenron Pharmaceuticals, Inc. | Use of a VEGF receptor-based fusion protein antagonist to treat nonproliferative diabetic retinopathy |
| US11519020B2 (en) | 2018-05-25 | 2022-12-06 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
| US12116622B2 (en) | 2018-05-25 | 2024-10-15 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2089059A2 (en) | 2009-08-19 |
| WO2008063932A2 (en) | 2008-05-29 |
| CA2666709A1 (en) | 2008-05-29 |
| US20120009185A1 (en) | 2012-01-12 |
| AU2007323925A1 (en) | 2008-05-29 |
| WO2008063932A3 (en) | 2008-09-04 |
| US20100111963A1 (en) | 2010-05-06 |
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