JP2010509281A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010509281A5 JP2010509281A5 JP2009535724A JP2009535724A JP2010509281A5 JP 2010509281 A5 JP2010509281 A5 JP 2010509281A5 JP 2009535724 A JP2009535724 A JP 2009535724A JP 2009535724 A JP2009535724 A JP 2009535724A JP 2010509281 A5 JP2010509281 A5 JP 2010509281A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- triazol
- propyl
- compound
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*1C=CC(c2n[n]nc2*)=C*(*)C=C1 Chemical compound C*1C=CC(c2n[n]nc2*)=C*(*)C=C1 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06380289A EP1921071A1 (en) | 2006-11-10 | 2006-11-10 | 1,2,3- triazole derivatives as sigma receptor inhibitors |
| PCT/EP2007/062010 WO2008055933A1 (en) | 2006-11-10 | 2007-11-07 | 1,2,3-triazole derivatives as sigma receptor inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010509281A JP2010509281A (ja) | 2010-03-25 |
| JP2010509281A5 true JP2010509281A5 (https=) | 2010-12-24 |
Family
ID=37963991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535724A Pending JP2010509281A (ja) | 2006-11-10 | 2007-11-07 | シグマ受容体阻害剤としての１，２，３−トリアゾール誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8193223B2 (https=) |
| EP (2) | EP1921071A1 (https=) |
| JP (1) | JP2010509281A (https=) |
| KR (1) | KR20090087032A (https=) |
| CN (1) | CN101589029A (https=) |
| AU (1) | AU2007316606A1 (https=) |
| BR (1) | BRPI0718586A2 (https=) |
| CA (1) | CA2668996A1 (https=) |
| ES (1) | ES2413559T3 (https=) |
| MX (1) | MX2009004745A (https=) |
| RU (1) | RU2009122198A (https=) |
| WO (1) | WO2008055933A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2116539A1 (en) | 2008-04-25 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof |
| EP2353591A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof |
| EP2388005A1 (en) | 2010-05-21 | 2011-11-23 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy |
| EP2395003A1 (en) | 2010-05-27 | 2011-12-14 | Laboratorios Del. Dr. Esteve, S.A. | Pyrazole compounds as sigma receptor inhibitors |
| EP2415471A1 (en) | 2010-08-03 | 2012-02-08 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in opioid-induced hyperalgesia |
| EP2524694A1 (en) | 2011-05-19 | 2012-11-21 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in diabetes type-2 associated pain |
| EP2548878A1 (en) * | 2011-07-21 | 2013-01-23 | Laboratorios Del. Dr. Esteve, S.A. | Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligands |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2752411A1 (en) | 2013-01-07 | 2014-07-09 | Laboratorios Del Dr. Esteve, S.A. | 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders |
| EP2792679A1 (en) * | 2013-04-19 | 2014-10-22 | Laboratorios Del. Dr. Esteve, S.A. | Tricyclic triazolic compounds |
| WO2014173901A1 (en) | 2013-04-23 | 2014-10-30 | Laboratorios Del Dr. Esteve, S.A. | PYRAZINO[1,2-a]INDOLE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS |
| ES2786052T3 (es) | 2013-04-23 | 2020-10-08 | Esteve Pharmaceuticals Sa | Compuestos de pirazino[1,2-a]indol, su preparación y su uso en medicamentos |
| EP2832720A1 (en) | 2013-07-30 | 2015-02-04 | Laboratorios Del. Dr. Esteve, S.A. | 1,2-disubstituted cyclobutyl compounds |
| TW201607538A (zh) | 2013-12-17 | 2016-03-01 | 以斯提夫博士實驗室股份有限公司 | 血清素－去甲腎上腺素再攝取抑制劑（ＳＮＲＩＳ）和σ受體配體組合物 |
| MA41177A (fr) * | 2014-12-15 | 2017-10-24 | Esteve Labor Dr | Utilisation de ligands des récepteurs sigma dans l'arthrose |
| AU2016211292B2 (en) | 2015-01-30 | 2020-05-07 | Neurocrine Biosciences, Inc. | Substituted triazoles and methods relating thereto |
| CN106866555B (zh) * | 2017-02-08 | 2019-04-30 | 东南大学 | 1-二苯甲基-4-甲基哌嗪类化合物其制备方法和应用 |
| EP3893892A4 (en) * | 2018-12-12 | 2022-09-14 | Rutgers, the State University of New Jersey | ORGANIC COMPOUNDS |
| CN116178286B (zh) * | 2021-11-26 | 2024-12-03 | 华东师范大学 | 一种n2烷基取代的三氮唑衍生物及其合成方法与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0507863A4 (en) | 1989-12-28 | 1993-07-07 | Virginia Commonwealth University | Sigma receptor ligands and the use thereof |
| EP1343497A4 (en) * | 2000-11-02 | 2005-01-26 | K And K Biosciences Inc | ANTICONVULSIVE AGENTS BASED ON $ G (D) -2, -1,2,3-TRIAZOLINE AND THEIR METABOLIC ACTIVE ANALOGUES, AMINOALKYLPYRIDINES, EXCITATOR AMINO ACID ANTAGONISTS AND ANTI-ISCHEMIC AGENTS USEFUL IN THE TREATMENT OF RESULTING BRAIN ISCHEMIA AN ATTACK |
| US20090258885A1 (en) * | 2005-11-04 | 2009-10-15 | Armstrong Helen M | Diphenylmethane Derivatives as Inhibitors of Leukotriene Biosynthesis |
-
2006
- 2006-11-10 EP EP06380289A patent/EP1921071A1/en not_active Withdrawn
-
2007
- 2007-11-07 RU RU2009122198/04A patent/RU2009122198A/ru not_active Application Discontinuation
- 2007-11-07 EP EP07822321A patent/EP2097392B1/en not_active Not-in-force
- 2007-11-07 KR KR1020097011468A patent/KR20090087032A/ko not_active Withdrawn
- 2007-11-07 BR BRPI0718586-3A2A patent/BRPI0718586A2/pt not_active Application Discontinuation
- 2007-11-07 ES ES07822321T patent/ES2413559T3/es active Active
- 2007-11-07 CN CNA2007800418260A patent/CN101589029A/zh active Pending
- 2007-11-07 CA CA002668996A patent/CA2668996A1/en not_active Abandoned
- 2007-11-07 WO PCT/EP2007/062010 patent/WO2008055933A1/en not_active Ceased
- 2007-11-07 AU AU2007316606A patent/AU2007316606A1/en not_active Abandoned
- 2007-11-07 US US12/514,213 patent/US8193223B2/en not_active Expired - Fee Related
- 2007-11-07 JP JP2009535724A patent/JP2010509281A/ja active Pending
- 2007-11-07 MX MX2009004745A patent/MX2009004745A/es not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010509281A5 (https=) | ||
| JP2010509280A5 (https=) | ||
| RU2009122198A (ru) | Производные 1,2,3-триазола в качестве ингибиторов сигма-рецепторов | |
| RU2009122197A (ru) | Производные 1,2,4-триазолы в качестве ингибиторов сигма-рецептора | |
| DK145644B (da) | Analogifremgangsmaade til fremstilling af imidazolforbindelser | |
| HU220088B (hu) | Tetrahidro-piridin- (vagy -4-hidroxi-piperidin)-alkil-azol-származékok és alkalmazásuk | |
| JP5391269B2 (ja) | ピペラジン化合物、それを含む医薬組成物 | |
| HUE034430T2 (en) | Process for the preparation of triazole compounds | |
| EP3452467A1 (de) | Verfahren zur herstellung von 5-hydroxyalkyl-substituierten 1-phenyl-1,2,4-triazolderivativen | |
| JP2016540793A5 (https=) | ||
| JP2009528319A5 (https=) | ||
| CN1169798C (zh) | 新型三氮唑醇类抗真菌化合物及其制备方法 | |
| US8772299B2 (en) | Phenyl piperazine compounds, pharmaceutical composition including the same and use thereof | |
| PT841327E (pt) | Agente anti-fungico de triazole | |
| DE60013515T2 (de) | 4-Arylpiperidinderivate zur Behandlung von Pruritus | |
| CA2249529A1 (en) | New triazoles as therapeutic agents for fungal infections | |
| US4785117A (en) | 5,5-disubstituted-3-phenyl-3-phenyl-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2-methylisoxazolidine derivatives (IR 3012) | |
| US4835283A (en) | 3,5-diphenyl-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2 | |
| US4767868A (en) | 3-Phenyl-3-(1H-imidazol-1-ylmethyl)-2-methyl-5-[(phenylamino)methyl]isoxazolidines | |
| EP0310061A1 (en) | 5-Mono or Disubstituted-3-(phenyl or 2-naphthalenyl)-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2-(methyl or benzyl)isoxazolidines | |
| US4831154A (en) | 5-alkyl(or alkenyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines | |
| US4767867A (en) | 5-(alkoxyalkyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines | |
| JP2005272450A5 (https=) | ||
| US4777264A (en) | 5-carbonyl derivatives of 3-phenyl-3-(1H-imadazol-1-ylmethyl)-2-methylisoxazolidines and related compounds thereof |