JP2010507619A - オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 - Google Patents
オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 Download PDFInfo
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- JP2010507619A JP2010507619A JP2009533834A JP2009533834A JP2010507619A JP 2010507619 A JP2010507619 A JP 2010507619A JP 2009533834 A JP2009533834 A JP 2009533834A JP 2009533834 A JP2009533834 A JP 2009533834A JP 2010507619 A JP2010507619 A JP 2010507619A
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- Prior art keywords
- oxadiazol
- phenyl
- pyridine
- pyridin
- benzonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85407806P | 2006-10-25 | 2006-10-25 | |
| DKPA200601380 | 2006-10-25 | ||
| PCT/EP2007/061433 WO2008049864A1 (en) | 2006-10-25 | 2007-10-24 | Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010507619A true JP2010507619A (ja) | 2010-03-11 |
| JP2010507619A5 JP2010507619A5 (enExample) | 2010-08-05 |
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|---|---|---|---|
| JP2009533834A Abandoned JP2010507619A (ja) | 2006-10-25 | 2007-10-24 | オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100029685A1 (enExample) |
| EP (1) | EP2079734A1 (enExample) |
| JP (1) | JP2010507619A (enExample) |
| AU (1) | AU2007310897A1 (enExample) |
| CA (1) | CA2667545A1 (enExample) |
| IL (1) | IL197397A0 (enExample) |
| MX (1) | MX2009003892A (enExample) |
| NO (1) | NO20091977L (enExample) |
| WO (1) | WO2008049864A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013544792A (ja) * | 2010-10-22 | 2013-12-19 | バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー | 殺害虫剤としての新規ヘテロ環式化合物 |
| JP2019500352A (ja) * | 2015-12-10 | 2019-01-10 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
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| ES2655466T3 (es) | 2007-08-13 | 2018-02-20 | Monsanto Technology Llc | Composiciones y procedimientos de control de nematodos |
| AU2013203849B2 (en) * | 2007-08-13 | 2016-01-14 | Monsanto Technology Llc | Compositions and methods for controlling nematodes |
| GB0723719D0 (en) * | 2007-12-04 | 2008-01-16 | Glaxo Group Ltd | Compounds |
| GB0723815D0 (en) * | 2007-12-05 | 2008-01-16 | Glaxo Group Ltd | Compounds |
| WO2009149135A1 (en) * | 2008-06-04 | 2009-12-10 | Abbott Laboratories | Bis (hetero ) aryl substituted isoxazoles for use as neuronal nicotinic receptor modulators |
| CA2730844A1 (en) * | 2008-07-17 | 2010-01-21 | Thomas Bretschneider | Heterocyclic compounds used as pesticides |
| KR20110050680A (ko) * | 2008-09-02 | 2011-05-16 | 뉴로서치 에이/에스 | 트리아졸 유도체, 및 니코틴성 아세틸콜린 수용체 조절제로서의 이들의 용도 |
| HUE025314T2 (en) | 2009-02-10 | 2016-02-29 | Monsanto Technology Llc | Preparations and procedures for controlling nematodes |
| WO2011047129A1 (en) | 2009-10-15 | 2011-04-21 | Southern Research Institute | Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such |
| WO2011073299A1 (en) | 2009-12-18 | 2011-06-23 | Neurosearch A/S | Pyridinyl oxadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
| EP2568809A4 (en) | 2010-05-12 | 2013-11-06 | Univ Vanderbilt | HETEROCYCLIC ALLOSTERE SULFON MGLUR4 POTENTIATORS, COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTIONS |
| JP5826848B2 (ja) | 2010-09-02 | 2015-12-02 | モンサント テクノロジー エルエルシー | 線虫を防除する新規組成物および方法 |
| EP2967065A4 (en) | 2013-03-15 | 2016-08-24 | Monsanto Technology Llc | N-, C-SUBSTITUTED AZOLE FOR COMBATING NEMATODE PENINS |
| CZ305680B6 (cs) * | 2013-04-04 | 2016-02-03 | Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové | Substituovaný diazol, jeho použití a farmaceutický přípravek ho obsahující |
| US10513110B2 (en) * | 2014-06-13 | 2019-12-24 | Electronics For Imaging, Inc. | Integration of a line-scan camera on a single pass inkjet printer |
| EP4151627A1 (en) | 2017-06-05 | 2023-03-22 | PTC Therapeutics, Inc. | Compounds for treating huntington's disease |
| CN111182898B (zh) | 2017-06-28 | 2024-04-16 | Ptc医疗公司 | 用于治疗亨廷顿氏病的方法 |
| CN111163838B (zh) | 2017-06-28 | 2023-03-28 | Ptc医疗公司 | 用于治疗亨廷顿氏病的方法 |
| BR112020019373A2 (pt) | 2018-03-27 | 2020-12-29 | Ptc Therapeutics, Inc. | Compostos para o tratamento da doença de hutington |
| IL279688B2 (en) | 2018-06-27 | 2025-01-01 | Ptc Therapeutics Inc | Heterocyclic and heteroaryl compounds for the treatment of Huntington's disease |
| WO2020005882A1 (en) | 2018-06-27 | 2020-01-02 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating huntington's disease |
| KR20210038845A (ko) | 2018-06-27 | 2021-04-08 | 피티씨 테라퓨틱스, 인크. | 헌팅턴병 치료를 위한 헤테로아릴 화합물 |
| CA3139821A1 (en) | 2019-05-13 | 2020-11-19 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| BR112022003959A2 (pt) * | 2019-09-05 | 2022-05-24 | Trevena Inc | Métodos para tratamento de epilepsia |
| MX2022005766A (es) | 2019-11-19 | 2022-08-08 | Trevena Inc | Compuestos y métodos para la preparación de compuestos moduladores de esfingosina 1-fosfato tipo 1 (s1p1). |
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| NL261797A (enExample) * | 1960-03-01 | |||
| CH411906A (de) * | 1960-03-01 | 1966-04-30 | Ciba Geigy | Verfahren zur Herstellung neuer 1,3,4-Thiadiazole |
| NL287227A (enExample) * | 1961-12-28 | |||
| US3574842A (en) * | 1969-11-10 | 1971-04-13 | American Cyanamid Co | Compositions of 4-(1,2,4-oxadiazole-3 or 5-yl)pyridinium salts and method of lowering blood sugar levels with same |
| US3964896A (en) * | 1971-08-09 | 1976-06-22 | Uniroyal, Inc. | Oxadiazole benzoic acid derivatives as herbicides |
| US3947263A (en) * | 1974-07-29 | 1976-03-30 | Uniroyal, Inc. | Plant growth regulants |
| EP0288432A1 (de) * | 1987-04-09 | 1988-10-26 | Ciba-Geigy Ag | Schädlingsbekämpfungsmittel |
| FR2636628B1 (fr) * | 1988-08-25 | 1990-12-28 | Sanofi Sa | Derives du thiadiazole-1,3,4, leur procede d'obtention et compositions pharmaceutiques en contenant |
| JP2801269B2 (ja) * | 1989-07-10 | 1998-09-21 | キヤノン株式会社 | 化合物およびこれを含む液晶組成物およびこれを使用した液晶素子 |
| US5670526A (en) * | 1995-12-21 | 1997-09-23 | Otsuka Pharmaceutical Co., Ltd. | 1,3,4-oxadiazoles |
| PL334570A1 (en) * | 1997-01-14 | 2000-03-13 | Egyt Gyogyszervegyeszeti Gyar | Derivatives of 2-(1,2,4-triazol-1-yl)-1,3,4-thiadiazole acting on central nervous system and hearth |
| US6699853B2 (en) * | 1997-06-16 | 2004-03-02 | Hoechst Schering Agrevo Gmbh | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides |
| DE19725450A1 (de) * | 1997-06-16 | 1998-12-17 | Hoechst Schering Agrevo Gmbh | 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclylpyrimidine, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| AR032653A1 (es) * | 2001-02-09 | 2003-11-19 | Telik Inc | Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos. |
| PL369598A1 (en) * | 2001-02-21 | 2005-05-02 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| US7041685B2 (en) * | 2001-06-08 | 2006-05-09 | Cytovia, Inc. | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| FR2832712B1 (fr) * | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique |
| FR2832713B1 (fr) * | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique |
| KR20060125885A (ko) * | 2004-02-04 | 2006-12-06 | 뉴로서치 에이/에스 | 콜린 수용체 조절제로서의 디아자바이사이클릭 아릴 유도체 |
| GB0403744D0 (en) * | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Chemical process |
| EP1758579A1 (en) * | 2004-05-29 | 2007-03-07 | 7TM Pharma A/S | Crth2 receptor ligands for medicinal uses |
| NZ571288A (en) * | 2006-05-30 | 2011-05-27 | Neurosearch As | Novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use |
| US20080015193A1 (en) * | 2006-06-20 | 2008-01-17 | Mendoza Jose S | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof |
| US8147807B2 (en) * | 2006-07-20 | 2012-04-03 | National University Corporation Okayama University | Oral composition for dental purposes |
| JP2010536839A (ja) * | 2007-08-17 | 2010-12-02 | アストラゼネカ アクチボラグ | 化合物９７９ |
| EP2195311B1 (en) * | 2007-08-17 | 2011-03-23 | Actelion Pharmaceuticals Ltd. | Pyridine derivatives as s1p1/edg1 receptor modulators |
| KR20100101165A (ko) * | 2007-12-26 | 2010-09-16 | 사노피-아벤티스 | 사이클릭 피리딜ｎ（１,３,４）티아디아졸２일-벤젠 설폰아미드, 이들의 제조방법 및 약제로서의 이들의 용도 |
| NZ589694A (en) * | 2008-06-09 | 2012-05-25 | Sanofi Aventis | Annelated n-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals |
| WO2010117662A1 (en) * | 2009-03-30 | 2010-10-14 | Exelixis, Inc. | Modulators of s1p and methods of making and using |
| SA110310332B1 (ar) * | 2009-05-01 | 2013-12-10 | Astrazeneca Ab | مركبات ميثانون (3 استبدال -ازيتيدين -1-يل )(5- فينيل -1، 3، 4- أوكساديازول -2-يل ) |
| US8399451B2 (en) * | 2009-08-07 | 2013-03-19 | Bristol-Myers Squibb Company | Heterocyclic compounds |
-
2007
- 2007-10-24 EP EP07821796A patent/EP2079734A1/en not_active Withdrawn
- 2007-10-24 MX MX2009003892A patent/MX2009003892A/es not_active Application Discontinuation
- 2007-10-24 JP JP2009533834A patent/JP2010507619A/ja not_active Abandoned
- 2007-10-24 AU AU2007310897A patent/AU2007310897A1/en not_active Abandoned
- 2007-10-24 CA CA002667545A patent/CA2667545A1/en not_active Abandoned
- 2007-10-24 US US12/447,205 patent/US20100029685A1/en not_active Abandoned
- 2007-10-24 WO PCT/EP2007/061433 patent/WO2008049864A1/en not_active Ceased
-
2009
- 2009-03-04 IL IL197397A patent/IL197397A0/en unknown
- 2009-05-20 NO NO20091977A patent/NO20091977L/no not_active Application Discontinuation
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013544792A (ja) * | 2010-10-22 | 2013-12-19 | バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー | 殺害虫剤としての新規ヘテロ環式化合物 |
| US9173396B2 (en) | 2010-10-22 | 2015-11-03 | Bayer Intellectual Property Gmbh | Heterocyclic compounds as pesticides |
| JP2019500352A (ja) * | 2015-12-10 | 2019-01-10 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP2021028331A (ja) * | 2015-12-10 | 2021-02-25 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP2021042211A (ja) * | 2015-12-10 | 2021-03-18 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP7025508B2 (ja) | 2015-12-10 | 2022-02-24 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP7053760B2 (ja) | 2015-12-10 | 2022-04-12 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100029685A1 (en) | 2010-02-04 |
| EP2079734A1 (en) | 2009-07-22 |
| AU2007310897A1 (en) | 2008-05-02 |
| WO2008049864A1 (en) | 2008-05-02 |
| IL197397A0 (en) | 2009-12-24 |
| NO20091977L (no) | 2009-05-20 |
| MX2009003892A (es) | 2009-04-23 |
| CA2667545A1 (en) | 2008-05-02 |
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