JP2010505836A5 - - Google Patents

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Publication number
JP2010505836A5
JP2010505836A5 JP2009531440A JP2009531440A JP2010505836A5 JP 2010505836 A5 JP2010505836 A5 JP 2010505836A5 JP 2009531440 A JP2009531440 A JP 2009531440A JP 2009531440 A JP2009531440 A JP 2009531440A JP 2010505836 A5 JP2010505836 A5 JP 2010505836A5
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JP
Japan
Prior art keywords
composition
disease
radiation
cancer
renal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009531440A
Other languages
English (en)
Japanese (ja)
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JP2010505836A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/021259 external-priority patent/WO2008060372A2/en
Publication of JP2010505836A publication Critical patent/JP2010505836A/ja
Publication of JP2010505836A5 publication Critical patent/JP2010505836A5/ja
Withdrawn legal-status Critical Current

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JP2009531440A 2006-10-04 2007-10-02 ヒンバシンの修飾された三環単位に基づいたトロンビン受容体アンタゴニスト Withdrawn JP2010505836A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84928406P 2006-10-04 2006-10-04
PCT/US2007/021259 WO2008060372A2 (en) 2006-10-04 2007-10-02 Thrombin receptor antagonists based on the modified tricyclic unit of himbacine

Publications (2)

Publication Number Publication Date
JP2010505836A JP2010505836A (ja) 2010-02-25
JP2010505836A5 true JP2010505836A5 (enExample) 2010-04-22

Family

ID=39284222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009531440A Withdrawn JP2010505836A (ja) 2006-10-04 2007-10-02 ヒンバシンの修飾された三環単位に基づいたトロンビン受容体アンタゴニスト

Country Status (12)

Country Link
US (1) US20080085923A1 (enExample)
EP (1) EP2078012A2 (enExample)
JP (1) JP2010505836A (enExample)
KR (1) KR20090058583A (enExample)
CN (1) CN101553484A (enExample)
AR (1) AR063095A1 (enExample)
AU (1) AU2007320029A1 (enExample)
CA (1) CA2666903A1 (enExample)
IL (1) IL198011A0 (enExample)
MX (1) MX2009003758A (enExample)
TW (1) TW200823206A (enExample)
WO (1) WO2008060372A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8227412B2 (en) * 2007-03-29 2012-07-24 Tsopanoglou Nikos E Bioactive parstatin peptides and methods of use
MX2011012861A (es) * 2009-06-04 2012-01-25 Schering Corp Metabolito activo de un antagonista de receptor de trombina.
WO2011041217A1 (en) * 2009-10-02 2011-04-07 Schering Corporation The use of a par-1 antagonist in combination with a p2y12adp receptor antagonist for inhibition of thrombosis
CN105777681B (zh) * 2014-12-17 2019-03-01 博瑞生物医药(苏州)股份有限公司 喜巴辛类似物及其中间体的制备方法
JPWO2016114386A1 (ja) * 2015-01-15 2017-10-19 国立研究開発法人国立精神・神経医療研究センター 進行型免疫性脱髄疾患治療剤
CN105985303B (zh) * 2015-02-13 2020-08-14 上海彩迩文生化科技有限公司 抗凝血剂的制备方法、中间体及其制备方法
CN106866450B (zh) * 2017-01-13 2019-01-11 阜阳欣奕华材料科技有限公司 硫酸沃拉帕沙中间体的制备方法
CN110483455A (zh) * 2019-09-29 2019-11-22 天津力生制药股份有限公司 一种硫酸沃拉帕沙中间体醛基物的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063847A (en) * 1997-11-25 2000-05-16 Schering Corporation Thrombin receptor antagonists
MY130642A (en) * 2000-06-15 2007-07-31 Schering Corp Nor-seco himbacine derivatives useful as thrombin receptor antagonists
MXPA04003610A (es) * 2001-10-18 2004-07-27 Schering Corp Analogos de himbacina como antagonistas del receptor de trombina.
ATE378330T1 (de) * 2002-04-16 2007-11-15 Schering Corp Trizyklische thrombin rezeptor antagonisten

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