JP2010505109A - 小型閾値センサ - Google Patents
小型閾値センサ Download PDFInfo
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- JP2010505109A JP2010505109A JP2009529837A JP2009529837A JP2010505109A JP 2010505109 A JP2010505109 A JP 2010505109A JP 2009529837 A JP2009529837 A JP 2009529837A JP 2009529837 A JP2009529837 A JP 2009529837A JP 2010505109 A JP2010505109 A JP 2010505109A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
- A61B2562/0214—Capacitive electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
- A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
- A61M2210/1053—Stomach
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
C=(ε0*εr*A)/d
ここで、ε0は自由空間の誘電率を表す定数で、εrは誘電体の組成及び厚さに従って変化する誘電率である。
Claims (22)
- サイズが小型であって低消費電力の複数の電極;及び
該電極の外側に設けられたコーティング;
を有するセンサであって、
前記コーティングは標的状態と相互作用し、
該相互作用により、前記電極表面での物理特性、電気特性、及び化学特性のうちの少なくとも1つが変化し、かつ
該変化は前記電極によって電気信号に変換される、
センサ。 - 空洞内で用いられる、請求項1に記載のセンサ。
- 体腔内で用いられる、請求項2に記載のセンサ。
- 前記体腔が、胃腸管、腹膜管、腹管、脳脊髄腔、肺、泌尿生殖器腔、血管、皮下部位、及び筋肉内部位からなる群から選ばれる、請求項3に記載のセンサ。
- 前記空洞は、建築構造物での位置、地下での位置、水中での位置、大気中での位置、農業での位置、及び自然発生した位置からなる群から選ばれる、請求項2に記載のセンサ。
- 前記低電力消費が少なくとも0.1μワットから10μワットである、請求項1に記載のセンサ。
- 前記低電力消費が少なくとも50μワットから1000μワットである、請求項1に記載のセンサ。
- 前記コーティングがpH感受性のポリマーを有する、請求項1に記載のセンサ。
- 前記コーティングは、ヒドロゲル、及び該ヒドロゲルと標的状態との相互作用を有し、かつ該標的状態は前記ヒドロゲルの水和を変化させる、
請求項1に記載のセンサ。 - 前記標的状態は、炎症性物質、酵素、水素イオン、及びヒドロキシルラジカルのうちの少なくとも1種類の存在を含む、請求項1に記載のセンサ。
- 前記電気特性の変化にはたとえばキャパシタンスの変化が含まれる、請求項1に記載のセンサ。
- 前記キャパシタンスの変化が、電流、電位、及びインピーダンスからなる群から選ばれる少なくとも1つのパラメータを測定することによって検出される、請求項11に記載のセンサ。
- 錠剤と一体化して用いられ、かつ
前記錠剤とセンサ装置を形成する、
請求項1に記載のセンサ。 - 組成物を空洞へ供給するセンサと錠剤を有するセンサ装置の使用方法であって:
前記装置を前駆空洞へ挿入する手順であって、前記センサはサイズが小型でかつ低消費電力である複数の電極及び該電極の外側に設けられたコーティングを有し、前記錠剤は組成物、ポンプ、及び電子機器の容器を供し、該電子機器は少なくとも1つの回路を有する、手順;
標的状態を検出する手順であって、該標的状態は前記コーティングと相互作用することで、物理特性、電気特性、及び化学特性のうちの少なくとも1つを変化させ、前記変化は前記電極の表面で生じ、前記センサは前記変化を電気信号に変換し、かつ該信号は前記少なくとも1つの回路によって検出される、手順;並びに、
前記組成物を標的位置に投与する手順であって、前記組成物を空洞へ供給するセンサと錠剤を有するセンサ装置を使用するため、前記組成物は前記容器内に保持され、かつ前記ポンプを用いて供給される、手順;
を有する方法。 - 前記装置は体腔内で使用される、請求項14に記載の方法。
- 前記体腔は、胃腸管、腹膜管、腹管、脳脊髄腔、肺、泌尿生殖器腔、及び血管からなる群から選ばれる、請求項15に記載の方法。
- 前記標的状態を検出する手順は、前記変化を保存された閾値と比較する手順をさらに有する、請求項14に記載の方法。
- 前記コーティングはpH感受性のポリマーを有する、請求項14に記載の方法。
- 前記コーティングは、ヒドロゲル、及び該ヒドロゲルと標的状態との相互作用を有し、かつ該標的状態は前記ヒドロゲルの水和を変化させる、
請求項14に記載の方法。 - 前記電気特性の変化にはたとえばキャパシタンスの変化が含まれる、請求項14に記載の方法。
- 前記キャパシタンスの変化が、電流、電位、及びインピーダンスからなる群から選ばれる少なくとも1つのパラメータを測定することによって検出される、請求項20に記載の方法。
- 組成物を空洞へ供給するシステムであって:
センサと錠剤を有するセンサ装置であって、
前記センサはサイズが小型でかつ低消費電力である複数の電極及び該電極の外側に設けられたコーティングを有し、
前記錠剤は、組成物、ポンプ、及び電子機器の容器と、バッテリーを供し、前記電子機器は少なくとも1つの回路を有し、
前記センサの電極は、前記組成物の供給タイミングと供給位置のうちの少なくとも1つを制御するため、前記錠剤の電子機器と接続する、
センサ装置;並びに
空洞内の標的状態であって、
該標的状態は前記コーティングと相互作用することで、物理特性、電気特性、及び化学特性のうちの少なくとも1つを変化させ、
前記変化は前記電極によって電気信号に変換され、かつ該信号は前記少なくとも1つの回路によって検出される、
標的状態;
を有するシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82748806P | 2006-09-29 | 2006-09-29 | |
US60/827,488 | 2006-09-29 | ||
PCT/IB2007/053931 WO2008038246A2 (en) | 2006-09-29 | 2007-09-27 | Miniaturized threshold sensor |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010505109A true JP2010505109A (ja) | 2010-02-18 |
JP5987151B2 JP5987151B2 (ja) | 2016-09-07 |
Family
ID=39230657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009529837A Active JP5987151B2 (ja) | 2006-09-29 | 2007-09-27 | 小型閾値センサ |
Country Status (6)
Country | Link |
---|---|
US (1) | US9227011B2 (ja) |
EP (1) | EP2073698B1 (ja) |
JP (1) | JP5987151B2 (ja) |
CN (1) | CN101522094B (ja) |
RU (1) | RU2009116271A (ja) |
WO (1) | WO2008038246A2 (ja) |
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EP2073698B1 (en) | 2015-09-09 |
CN101522094A (zh) | 2009-09-02 |
JP5987151B2 (ja) | 2016-09-07 |
WO2008038246A2 (en) | 2008-04-03 |
WO2008038246A3 (en) | 2008-10-09 |
EP2073698A2 (en) | 2009-07-01 |
US20100033324A1 (en) | 2010-02-11 |
CN101522094B (zh) | 2013-12-18 |
US9227011B2 (en) | 2016-01-05 |
RU2009116271A (ru) | 2010-11-10 |
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