JP2010505104A - 膵管腺癌に関連する新規の抗原及び抗体 - Google Patents

膵管腺癌に関連する新規の抗原及び抗体 Download PDF

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Publication number
JP2010505104A
JP2010505104A JP2009529713A JP2009529713A JP2010505104A JP 2010505104 A JP2010505104 A JP 2010505104A JP 2009529713 A JP2009529713 A JP 2009529713A JP 2009529713 A JP2009529713 A JP 2009529713A JP 2010505104 A JP2010505104 A JP 2010505104A
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Prior art keywords
pda
enolase
antibodies
protein
antibody
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JP2009529713A
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English (en)
Japanese (ja)
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JP2010505104A5 (enExample
Inventor
ノベッリ，フランチェスコ
トマイノ，バルバラ
カペッロ，パオラ
Original Assignee
リボバックス バイオテクノロジーズ ソシエテ アノニム
ビオリネ ディアニョスティーチ ソチエタ レスポンサビリタ リミテ
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Publication of JP2010505104A publication Critical patent/JP2010505104A/ja
Publication of JP2010505104A5 publication Critical patent/JP2010505104A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • G01N33/57525—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
    • G01N33/575—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
JP2009529713A 2006-09-29 2007-09-28 膵管腺癌に関連する新規の抗原及び抗体 Pending JP2010505104A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06121552 2006-09-29
EP06126726 2006-12-20
PCT/EP2007/060305 WO2008037792A1 (en) 2006-09-29 2007-09-28 Novel antigens and antibodies associated to pancreatic ductal adenocarcinoma

Publications (2)

Publication Number Publication Date
JP2010505104A true JP2010505104A (ja) 2010-02-18
JP2010505104A5 JP2010505104A5 (enExample) 2010-10-07

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ID=38895810

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009529713A Pending JP2010505104A (ja) 2006-09-29 2007-09-28 膵管腺癌に関連する新規の抗原及び抗体

Country Status (18)

Country Link
US (1) US8071721B2 (enExample)
EP (1) EP2069395B1 (enExample)
JP (1) JP2010505104A (enExample)
KR (1) KR20090094227A (enExample)
CN (1) CN101578295B (enExample)
AT (1) ATE542831T1 (enExample)
AU (1) AU2007301966B2 (enExample)
BR (1) BRPI0717282A2 (enExample)
CA (1) CA2664841A1 (enExample)
DK (1) DK2069395T3 (enExample)
EA (1) EA016731B1 (enExample)
ES (1) ES2381304T3 (enExample)
IL (2) IL197868A (enExample)
NO (1) NO20091662L (enExample)
NZ (1) NZ576409A (enExample)
PL (1) PL2069395T3 (enExample)
PT (1) PT2069395E (enExample)
WO (1) WO2008037792A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009137832A2 (en) * 2008-05-09 2009-11-12 Duke University Autoantibodies in the detection and treatment of cancer
IT1398782B1 (it) * 2009-09-11 2013-03-18 Novelli Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.
ITTO20120523A1 (it) * 2012-06-15 2013-12-16 Natimab Therapeutics S R L Procedimento e kit per la diagnosi in vitro dell'adenocarcinoma duttale pancreatico o per determinare la predisposizione all'adenocarcinoma duttale pancreatico
EP3083697B1 (en) * 2013-12-20 2019-04-17 Development Center for Biotechnology Alpha-enolase specific antibodies and methods of uses in cancer therapy
WO2015106296A1 (en) 2014-01-13 2015-07-16 Berg Llc Enolse 1 (eno1) compositions and uses thereof
CN115786317A (zh) * 2022-12-12 2023-03-14 江苏三联生物工程股份有限公司 重组神经元特异性烯醇化酶及其制备方法与应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753446A (en) * 1993-04-15 1998-05-19 National Jewish Center For Immunology & Respiratory Medicine Mitogen ERK kinase kinase (MEKK) assay

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753446A (en) * 1993-04-15 1998-05-19 National Jewish Center For Immunology & Respiratory Medicine Mitogen ERK kinase kinase (MEKK) assay

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JPN6012046513; Ｎａｔ．　Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．２３，　Ｎｏ．１, 2005, ｐｐ．９４-１０１ *
JPN6012046516; Ｅｌｅｃｔｒｏｐｈｏｒｅｓｉｓ Ｖｏｌ．２１，　Ｎｏ．１３, 2000, ｐｐ．２６２２-２６３６ *
JPN6012046519; Ｍｏｌ．　Ｂｉｏｌ．　Ｃｅｌｌ Ｖｏｌ．１６，　Ｎｏ．１０, 2005, ｐｐ．４７６５-４７８０ *
JPN6012046520; Ｃａｎｃｅｒ　Ｒｅｓ． Ｖｏｌ．６４，　Ｎｏ．２４, 2004, ｐｐ．９０１８-９０２６ *
JPN6012046523; Ｊ．　Ｂｉｏｃｈｅｍ． Ｖｏｌ．１１７，　Ｎｏ．３, 1995, ｐｐ．５５４-５５９ *
JPN6012046525; Ｊ．　Ｉｍｍｕｎｏｌ． Ｖｏｌ．１７６，　Ｓｕｐｐｌｅｍｅｎｔ, 20060401, ｐ．Ｓ２６８ *

Also Published As

Publication number Publication date
AU2007301966B2 (en) 2013-02-21
ES2381304T3 (es) 2012-05-25
AU2007301966A1 (en) 2008-04-03
KR20090094227A (ko) 2009-09-04
WO2008037792A1 (en) 2008-04-03
IL218442A0 (en) 2012-04-30
IL197868A0 (en) 2011-08-01
EA200970332A1 (ru) 2009-10-30
CA2664841A1 (en) 2008-04-03
ATE542831T1 (de) 2012-02-15
PT2069395E (pt) 2012-04-27
US8071721B2 (en) 2011-12-06
NZ576409A (en) 2012-02-24
IL197868A (en) 2013-03-24
US20100028907A1 (en) 2010-02-04
BRPI0717282A2 (pt) 2013-10-15
EP2069395A1 (en) 2009-06-17
CN101578295B (zh) 2013-02-27
NO20091662L (no) 2009-06-29
PL2069395T3 (pl) 2012-06-29
DK2069395T3 (da) 2012-05-14
EA016731B1 (ru) 2012-07-30
EP2069395B1 (en) 2012-01-25
CN101578295A (zh) 2009-11-11

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