AU2007301966B2 - Novel antigens and antibodies associated to Pancreatic Ductal Adenocarcinoma - Google Patents

Novel antigens and antibodies associated to Pancreatic Ductal Adenocarcinoma Download PDF

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Publication number
AU2007301966B2
AU2007301966B2 AU2007301966A AU2007301966A AU2007301966B2 AU 2007301966 B2 AU2007301966 B2 AU 2007301966B2 AU 2007301966 A AU2007301966 A AU 2007301966A AU 2007301966 A AU2007301966 A AU 2007301966A AU 2007301966 B2 AU2007301966 B2 AU 2007301966B2
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AU
Australia
Prior art keywords
pda
enolase
alpha
antibodies
enoa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007301966A
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English (en)
Other versions
AU2007301966A1 (en
Inventor
Paola Cappello
Francesco Novelli
Barbara Tomaino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ribovax Biotechnologies SA
Bioline Diagnostici SRL
Original Assignee
Ribovax Biotechnologies SA
Bioline Diagnostici SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribovax Biotechnologies SA, Bioline Diagnostici SRL filed Critical Ribovax Biotechnologies SA
Publication of AU2007301966A1 publication Critical patent/AU2007301966A1/en
Application granted granted Critical
Publication of AU2007301966B2 publication Critical patent/AU2007301966B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • G01N33/57525—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
    • G01N33/575—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
AU2007301966A 2006-09-29 2007-09-28 Novel antigens and antibodies associated to Pancreatic Ductal Adenocarcinoma Ceased AU2007301966B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06121552.1 2006-09-29
EP06121552 2006-09-29
EP06126726.6 2006-12-20
EP06126726 2006-12-20
PCT/EP2007/060305 WO2008037792A1 (en) 2006-09-29 2007-09-28 Novel antigens and antibodies associated to pancreatic ductal adenocarcinoma

Publications (2)

Publication Number Publication Date
AU2007301966A1 AU2007301966A1 (en) 2008-04-03
AU2007301966B2 true AU2007301966B2 (en) 2013-02-21

Family

ID=38895810

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007301966A Ceased AU2007301966B2 (en) 2006-09-29 2007-09-28 Novel antigens and antibodies associated to Pancreatic Ductal Adenocarcinoma

Country Status (18)

Country Link
US (1) US8071721B2 (enExample)
EP (1) EP2069395B1 (enExample)
JP (1) JP2010505104A (enExample)
KR (1) KR20090094227A (enExample)
CN (1) CN101578295B (enExample)
AT (1) ATE542831T1 (enExample)
AU (1) AU2007301966B2 (enExample)
BR (1) BRPI0717282A2 (enExample)
CA (1) CA2664841A1 (enExample)
DK (1) DK2069395T3 (enExample)
EA (1) EA016731B1 (enExample)
ES (1) ES2381304T3 (enExample)
IL (2) IL197868A (enExample)
NO (1) NO20091662L (enExample)
NZ (1) NZ576409A (enExample)
PL (1) PL2069395T3 (enExample)
PT (1) PT2069395E (enExample)
WO (1) WO2008037792A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009137832A2 (en) * 2008-05-09 2009-11-12 Duke University Autoantibodies in the detection and treatment of cancer
IT1398782B1 (it) * 2009-09-11 2013-03-18 Novelli Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.
ITTO20120523A1 (it) * 2012-06-15 2013-12-16 Natimab Therapeutics S R L Procedimento e kit per la diagnosi in vitro dell'adenocarcinoma duttale pancreatico o per determinare la predisposizione all'adenocarcinoma duttale pancreatico
EP3083697B1 (en) * 2013-12-20 2019-04-17 Development Center for Biotechnology Alpha-enolase specific antibodies and methods of uses in cancer therapy
WO2015106296A1 (en) 2014-01-13 2015-07-16 Berg Llc Enolse 1 (eno1) compositions and uses thereof
CN115786317A (zh) * 2022-12-12 2023-03-14 江苏三联生物工程股份有限公司 重组神经元特异性烯醇化酶及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753446A (en) * 1993-04-15 1998-05-19 National Jewish Center For Immunology & Respiratory Medicine Mitogen ERK kinase kinase (MEKK) assay

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Marcus, et al., Electrophoresis. 2000, vol. 21, pages 2622-2636. *
Rush, et al. Nature BioTech. 2005, vol. 23, pages 94-101. *
Shen, J., et al., Cancer Research. 2004, vol. 64, pages 9018-9026. *
Stasyk, T. et al., Molecular Biology of the Cell, 2005, vol. 16, pages 4765-4780. *

Also Published As

Publication number Publication date
ES2381304T3 (es) 2012-05-25
AU2007301966A1 (en) 2008-04-03
KR20090094227A (ko) 2009-09-04
WO2008037792A1 (en) 2008-04-03
IL218442A0 (en) 2012-04-30
IL197868A0 (en) 2011-08-01
EA200970332A1 (ru) 2009-10-30
CA2664841A1 (en) 2008-04-03
ATE542831T1 (de) 2012-02-15
PT2069395E (pt) 2012-04-27
US8071721B2 (en) 2011-12-06
NZ576409A (en) 2012-02-24
IL197868A (en) 2013-03-24
JP2010505104A (ja) 2010-02-18
US20100028907A1 (en) 2010-02-04
BRPI0717282A2 (pt) 2013-10-15
EP2069395A1 (en) 2009-06-17
CN101578295B (zh) 2013-02-27
NO20091662L (no) 2009-06-29
PL2069395T3 (pl) 2012-06-29
DK2069395T3 (da) 2012-05-14
EA016731B1 (ru) 2012-07-30
EP2069395B1 (en) 2012-01-25
CN101578295A (zh) 2009-11-11

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