JP2010504756A5 - - Google Patents
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- Publication number
- JP2010504756A5 JP2010504756A5 JP2009530430A JP2009530430A JP2010504756A5 JP 2010504756 A5 JP2010504756 A5 JP 2010504756A5 JP 2009530430 A JP2009530430 A JP 2009530430A JP 2009530430 A JP2009530430 A JP 2009530430A JP 2010504756 A5 JP2010504756 A5 JP 2010504756A5
- Authority
- JP
- Japan
- Prior art keywords
- strain
- xylose
- ethanol
- glucose
- genetic modification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 28
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 22
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 14
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 14
- 230000000694 effects Effects 0.000 claims description 7
- 241000588901 Zymomonas Species 0.000 claims description 6
- 108010009512 Glucose-fructose oxidoreductase Proteins 0.000 claims description 5
- 238000012239 gene modification Methods 0.000 claims description 5
- 230000005017 genetic modification Effects 0.000 claims description 5
- 235000013617 genetically modified food Nutrition 0.000 claims description 5
- 238000012258 culturing Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 description 7
- 101001059186 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) Glucose-fructose oxidoreductase Proteins 0.000 description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 150000005846 sugar alcohols Chemical class 0.000 description 3
- 239000000811 xylitol Substances 0.000 description 3
- 235000010447 xylitol Nutrition 0.000 description 3
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 3
- 229960002675 xylitol Drugs 0.000 description 3
- 108020004705 Codon Proteins 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- 239000007836 KH2PO4 Substances 0.000 description 2
- 108700026244 Open Reading Frames Proteins 0.000 description 2
- 229940041514 candida albicans extract Drugs 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 2
- 235000019341 magnesium sulphate Nutrition 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 235000019796 monopotassium phosphate Nutrition 0.000 description 2
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000011218 seed culture Methods 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 239000012138 yeast extract Substances 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 206010010144 Completed suicide Diseases 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- JVWLUVNSQYXYBE-UHFFFAOYSA-N Ribitol Natural products OCC(C)C(O)C(O)CO JVWLUVNSQYXYBE-UHFFFAOYSA-N 0.000 description 1
- 238000012300 Sequence Analysis Methods 0.000 description 1
- 108091081024 Start codon Proteins 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- FBPFZTCFMRRESA-GUCUJZIJSA-N galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84785606P | 2006-09-28 | 2006-09-28 | |
| US60/847,856 | 2006-09-28 | ||
| PCT/US2007/020945 WO2008051348A2 (en) | 2006-09-28 | 2007-09-28 | Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010504756A JP2010504756A (ja) | 2010-02-18 |
| JP2010504756A5 true JP2010504756A5 (enExample) | 2010-10-21 |
| JP5185940B2 JP5185940B2 (ja) | 2013-04-17 |
Family
ID=39325091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009530430A Expired - Fee Related JP5185940B2 (ja) | 2006-09-28 | 2007-09-28 | キシロース資化性ザイモモナス（Ｚｙｍｏｍｏｎａｓ）のキシリトール合成変異体を使用するエタノール産生 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7741084B2 (enExample) |
| EP (1) | EP2066797B1 (enExample) |
| JP (1) | JP5185940B2 (enExample) |
| CN (1) | CN102124117B (enExample) |
| BR (1) | BRPI0715285A2 (enExample) |
| CA (1) | CA2659443A1 (enExample) |
| DE (1) | DE602007005823D1 (enExample) |
| WO (1) | WO2008051348A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7781191B2 (en) * | 2005-04-12 | 2010-08-24 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain a target chemical |
| BRPI0817151A8 (pt) * | 2007-10-30 | 2018-12-11 | Du Pont | micro-organismo recombinante e processo para gerar o micro-organismo |
| ATE506447T1 (de) | 2007-10-30 | 2011-05-15 | Du Pont | Verfahren zur herstellung von etahnol in einem xylose enthaltenden medium unter verwendung eines rekombinanten zymomonas stammes mit reduzierter hima expression |
| ES2627671T3 (es) * | 2008-03-27 | 2017-07-31 | E. I. Du Pont De Nemours And Company | Promotores de Zymomonas de alta expresión |
| CA2716585C (en) * | 2008-03-27 | 2017-05-09 | E.I. Du Pont De Nemours And Company | Zymomonas recombinant for substituted glyceraldehyde-3-phosphate dehydrogenase promoter and xylose isomerase gene for improved xylose utilization |
| US20100159521A1 (en) * | 2008-12-19 | 2010-06-24 | E. I. Du Pont De Nemours And Company | Ozone treatment of biomass to enhance enzymatic saccharification |
| US8247208B2 (en) | 2008-12-22 | 2012-08-21 | Alliance For Sustainable Energy Llc | Zymomonas with improved xylose utilization in stress conditions |
| US20110143408A1 (en) * | 2009-06-18 | 2011-06-16 | E. I. Du Pont De Nemours And Company | Zymomonas with improved arabinose utilization |
| WO2010151574A2 (en) | 2009-06-25 | 2010-12-29 | Shell Oil Company | Water injection systems and methods |
| CA2767259A1 (en) * | 2009-07-09 | 2011-01-13 | Verdezyne, Inc. | Engineered microorganisms with enhanced fermentation activity |
| WO2011046816A1 (en) | 2009-10-12 | 2011-04-21 | E. I. Du Pont De Nemours And Company | Methods to improve monomeric sugar release from lignocellulosic biomass following alkaline pretreatment |
| US8623623B2 (en) | 2010-06-29 | 2014-01-07 | E I Du Pont De Nemours And Company | Xylose utilization in recombinant Zymomonas |
| US8679822B2 (en) | 2010-06-29 | 2014-03-25 | E I Du Pont De Nemours And Company | Xylose utilization in recombinant zymomonas |
| WO2012047832A2 (en) | 2010-10-07 | 2012-04-12 | Shell Oil Company | Process for the production of alcohols from biomass |
| CN103189526B (zh) | 2010-11-05 | 2015-07-08 | 国际壳牌研究有限公司 | 处理生物质以产生可用于生物燃料的材料 |
| US8476048B2 (en) | 2010-12-17 | 2013-07-02 | E I Du Pont De Nemours And Company | Xylose utilizing zymomonas mobilis with improved ethanol production in biomass hydrolysate medium |
| WO2012088108A1 (en) | 2010-12-20 | 2012-06-28 | Shell Oil Company | Process for the production of alcohols from biomass |
| US8765426B2 (en) | 2011-04-07 | 2014-07-01 | E I Du Pont De Nemours And Company | Pantothenic acid biosynthesis in zymomonas |
| US20130157332A1 (en) | 2011-12-20 | 2013-06-20 | E I Du Pont De Nemours And Company | Gene inactivation allowing immediate growth on xylose medium by engineered zymomonas |
| US8911983B2 (en) | 2011-12-20 | 2014-12-16 | E I Du Pont De Nemours And Company | Pnp gene modification for improved xylose utilization in Zymomonas |
| CN107043791A (zh) | 2012-01-13 | 2017-08-15 | 东丽株式会社 | 化学品的制造方法 |
| CN104395478B (zh) | 2012-05-07 | 2017-07-28 | 国际壳牌研究有限公司 | 处理生物质以生产可用于生物燃料的材料的连续或半连续方法 |
| US8846357B2 (en) | 2012-12-20 | 2014-09-30 | E I Du Pont De Nemours And Company | Stabilized chlorine dioxide for contamination control in Zymomonas fermentation |
| US20150087041A1 (en) | 2013-09-26 | 2015-03-26 | E I Du Pont De Nemours And Company | Production of ethanol with reduced contaminants in a cellulosic biomass based process |
| US20150087040A1 (en) | 2013-09-26 | 2015-03-26 | E I Du Pont De Nemours And Company | Production of ethanol and recycle water in a cellulosic fermentation process |
| WO2015160887A1 (en) | 2014-04-17 | 2015-10-22 | Shell Oil Company | Processes for producing fermentation products |
| US9371546B2 (en) | 2014-06-24 | 2016-06-21 | E I Du Pont De Nemours And Company | Enhancing D-xylose and L-arabinose utilization in Zymomonas cells |
| WO2016025678A1 (en) | 2014-08-14 | 2016-02-18 | Shell Oil Company | Process for preparing furfural from biomass |
| BR112017002204B1 (pt) | 2014-08-14 | 2021-01-12 | Shell Internationale Research Maatschappij B.V. | métodos para recuperar ácido a-hidroxisulfônico em um processo de tratamento de biomassa |
| CN106536496A (zh) | 2014-08-14 | 2017-03-22 | 国际壳牌研究有限公司 | 从生物质制备糠醛的方法 |
| US10479773B2 (en) | 2016-05-03 | 2019-11-19 | Shell Oil Company | Lignin-based solvents and methods for their preparation |
| EP3535248A1 (en) | 2016-11-01 | 2019-09-11 | Shell Internationale Research Maatschappij B.V. | Process for the recovery of furfural |
| WO2018085182A1 (en) | 2016-11-01 | 2018-05-11 | Shell Oil Company | Process for the recovery of furfural |
| CA3039603A1 (en) | 2016-11-01 | 2018-05-11 | Shell Internationale Research Maatschappij B.V. | Process for the recovery of furfural |
| US10899725B2 (en) | 2016-11-01 | 2021-01-26 | Shell Oil Company | Process for the recovery of furfural |
| MX387881B (es) | 2016-12-21 | 2025-03-19 | Creatus Biosciences Inc | Metodo y organismo que expresa transportadores de xilosa de metschnikowia para aumentar la captacion de xilosa. |
| US11787773B2 (en) | 2019-05-22 | 2023-10-17 | Shell Usa, Inc. | Process for the production of furfural |
| AU2024212235A1 (en) | 2023-01-23 | 2025-07-03 | Shell Internationale Research Maatschappij B.V. | Method for treating grains to produce material useful for chemicals and biofuels |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5231020A (en) | 1989-03-30 | 1993-07-27 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
| JPH0466090A (ja) * | 1990-07-05 | 1992-03-02 | Shinenerugii Sangyo Gijutsu Sogo Kaihatsu Kiko | 異種遺伝子高発現ベクター |
| US5514583A (en) | 1994-04-15 | 1996-05-07 | Midwest Research Institute | Recombinant zymomonas for pentose fermentation |
| US5843760A (en) | 1994-04-15 | 1998-12-01 | Midwest Research Institute | Single zymomonas mobilis strain for xylose and arabinose fermentation |
| US5712133A (en) | 1994-04-15 | 1998-01-27 | Midwest Research Institute | Pentose fermentation by recombinant zymomonas |
| WO1995028476A1 (en) | 1994-04-15 | 1995-10-26 | Midwest Research Institute | Recombinant zymomonas for pentose fermentation |
| US7223575B2 (en) | 2000-05-01 | 2007-05-29 | Midwest Research Institute | Zymomonas pentose-sugar fermenting strains and uses thereof |
| US7374939B1 (en) | 2000-05-01 | 2008-05-20 | Midwest Research Institute | Method of inactivation of an end product of energy metabolism in Zymomonas mobilis |
| US7354755B2 (en) | 2000-05-01 | 2008-04-08 | Midwest Research Institute | Stable zymomonas mobilis xylose and arabinose fermenting strains |
| US6566107B1 (en) | 2000-11-01 | 2003-05-20 | Midwest Research Institute | Recombinant Zymomonas mobilis with improved xylose utilization |
| US20040231060A1 (en) | 2003-03-07 | 2004-11-25 | Athenix Corporation | Methods to enhance the activity of lignocellulose-degrading enzymes |
| CN1600850A (zh) | 2003-09-23 | 2005-03-30 | 中国农业科学院生物技术研究所 | 运动发酵单胞菌工程菌及其应用 |
-
2007
- 2007-09-27 US US11/862,736 patent/US7741084B2/en not_active Expired - Fee Related
- 2007-09-28 EP EP07867168A patent/EP2066797B1/en not_active Ceased
- 2007-09-28 BR BRPI0715285-0A2A patent/BRPI0715285A2/pt not_active IP Right Cessation
- 2007-09-28 DE DE602007005823T patent/DE602007005823D1/de active Active
- 2007-09-28 CA CA002659443A patent/CA2659443A1/en not_active Abandoned
- 2007-09-28 JP JP2009530430A patent/JP5185940B2/ja not_active Expired - Fee Related
- 2007-09-28 WO PCT/US2007/020945 patent/WO2008051348A2/en not_active Ceased
- 2007-09-28 CN CN200780035804.3A patent/CN102124117B/zh not_active Expired - Fee Related
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