JP2010504285A5 - - Google Patents
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- Publication number
- JP2010504285A5 JP2010504285A5 JP2009526743A JP2009526743A JP2010504285A5 JP 2010504285 A5 JP2010504285 A5 JP 2010504285A5 JP 2009526743 A JP2009526743 A JP 2009526743A JP 2009526743 A JP2009526743 A JP 2009526743A JP 2010504285 A5 JP2010504285 A5 JP 2010504285A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- group
- independently represents
- residue
- following formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- -1 amine compound Chemical class 0.000 claims 17
- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- 125000003118 aryl group Chemical group 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 150000001412 amines Chemical class 0.000 claims 5
- 229920000642 polymer Polymers 0.000 claims 5
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims 4
- 125000002723 alicyclic group Chemical group 0.000 claims 4
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims 4
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000003431 cross linking reagent Substances 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 201000005991 hyperphosphatemia Diseases 0.000 claims 4
- JCQKQWAONVEFJC-UHFFFAOYSA-N 3-hydroxy-2,2-bis(hydroxymethyl)propanal Chemical compound OCC(CO)(CO)C=O JCQKQWAONVEFJC-UHFFFAOYSA-N 0.000 claims 2
- YTBSYETUWUMLBZ-UHFFFAOYSA-N D-Erythrose Natural products OCC(O)C(O)C=O YTBSYETUWUMLBZ-UHFFFAOYSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-CBPJZXOFSA-N D-Gulose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O WQZGKKKJIJFFOK-CBPJZXOFSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-WHZQZERISA-N D-aldose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-WHZQZERISA-N 0.000 claims 2
- WQZGKKKJIJFFOK-IVMDWMLBSA-N D-allopyranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@@H]1O WQZGKKKJIJFFOK-IVMDWMLBSA-N 0.000 claims 2
- YTBSYETUWUMLBZ-IUYQGCFVSA-N D-erythrose Chemical compound OC[C@@H](O)[C@@H](O)C=O YTBSYETUWUMLBZ-IUYQGCFVSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 2
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims 2
- YTBSYETUWUMLBZ-QWWZWVQMSA-N D-threose Chemical compound OC[C@@H](O)[C@H](O)C=O YTBSYETUWUMLBZ-QWWZWVQMSA-N 0.000 claims 2
- 206010056474 Erythrosis Diseases 0.000 claims 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- LKDRXBCSQODPBY-AMVSKUEXSA-N L-(-)-Sorbose Chemical compound OCC1(O)OC[C@H](O)[C@@H](O)[C@@H]1O LKDRXBCSQODPBY-AMVSKUEXSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-VSOAQEOCSA-N L-altropyranose Chemical compound OC[C@@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-VSOAQEOCSA-N 0.000 claims 2
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims 2
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 2
- SRBFZHDQGSBBOR-STGXQOJASA-N alpha-D-lyxopyranose Chemical compound O[C@@H]1CO[C@H](O)[C@@H](O)[C@H]1O SRBFZHDQGSBBOR-STGXQOJASA-N 0.000 claims 2
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 2
- 229930182830 galactose Natural products 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000002951 idosyl group Chemical class C1([C@@H](O)[C@H](O)[C@@H](O)[C@H](O1)CO)* 0.000 claims 2
- 150000005846 sugar alcohols Chemical class 0.000 claims 2
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 150000002825 nitriles Chemical group 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- DFMPWLMMFFGNKY-QFSHWATDSA-N C=CCN(CCCN)CCCOCC(COCCCN(CCCN)CCCN)(COCCCN(CCCN)CCCN)COCCCN(CCCN)/C=C/CN Chemical compound C=CCN(CCCN)CCCOCC(COCCCN(CCCN)CCCN)(COCCCN(CCCN)CCCN)COCCCN(CCCN)/C=C/CN DFMPWLMMFFGNKY-QFSHWATDSA-N 0.000 description 1
- GDOPTJXRTPNYNR-UHFFFAOYSA-N CC1CCCC1 Chemical compound CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84156606P | 2006-09-01 | 2006-09-01 | |
| US84943406P | 2006-10-05 | 2006-10-05 | |
| US85344006P | 2006-10-23 | 2006-10-23 | |
| PCT/US2007/019201 WO2008027551A2 (en) | 2006-09-01 | 2007-08-31 | Dendrimer compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010504285A JP2010504285A (ja) | 2010-02-12 |
| JP2010504285A5 true JP2010504285A5 (cg-RX-API-DMAC7.html) | 2010-10-14 |
Family
ID=39136625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526743A Abandoned JP2010504285A (ja) | 2006-09-01 | 2007-08-31 | デンドリマー組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20100234309A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2068819A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010504285A (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0716066A2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008027551A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5093680B2 (ja) * | 2008-06-26 | 2012-12-12 | 独立行政法人産業技術総合研究所 | ビス四級アンモニウム塩コア型デンドリマー |
| MX348821B (es) | 2010-02-24 | 2017-06-30 | Relypsa Inc | Polímeros de amina para usarse como secuestrantes del ácido biliar. |
| US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
| KR20240152425A (ko) * | 2013-06-05 | 2024-10-21 | 트리시다, 인크. | 경구 투여를 위한 양성자-결합 중합체 |
| EP3718551A1 (en) | 2014-12-10 | 2020-10-07 | Tricida Inc. | Proton-binding polymers for oral administration |
| CN116211887A (zh) | 2016-05-06 | 2023-06-06 | 特里赛达公司 | 用于治疗酸碱失衡的组合物 |
| IL273960B2 (en) | 2017-11-03 | 2025-08-01 | Tricida Inc | Nonabsorable compositions for use in treating or preventing metabolic acidosis |
| CN109437415B (zh) * | 2018-10-12 | 2021-09-28 | 山东理工大学 | 无磷反渗透阻垢剂per-pamam及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5667775A (en) * | 1993-08-11 | 1997-09-16 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| US20030180250A1 (en) * | 2002-03-22 | 2003-09-25 | Council Of Scientific And Industrial Research | Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents |
-
2007
- 2007-08-31 US US12/310,514 patent/US20100234309A1/en not_active Abandoned
- 2007-08-31 EP EP07837624A patent/EP2068819A4/en not_active Withdrawn
- 2007-08-31 JP JP2009526743A patent/JP2010504285A/ja not_active Abandoned
- 2007-08-31 BR BRPI0716066-6A2A patent/BRPI0716066A2/pt not_active Application Discontinuation
- 2007-08-31 WO PCT/US2007/019201 patent/WO2008027551A2/en not_active Ceased
-
2014
- 2014-11-24 US US14/551,913 patent/US20150094379A1/en not_active Abandoned
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