JP2010286341A5 - - Google Patents
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- Publication number
- JP2010286341A5 JP2010286341A5 JP2009140043A JP2009140043A JP2010286341A5 JP 2010286341 A5 JP2010286341 A5 JP 2010286341A5 JP 2009140043 A JP2009140043 A JP 2009140043A JP 2009140043 A JP2009140043 A JP 2009140043A JP 2010286341 A5 JP2010286341 A5 JP 2010286341A5
- Authority
- JP
- Japan
- Prior art keywords
- light
- laser
- sample
- particularly limited
- measuring instrument
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000001514 detection method Methods 0.000 description 9
- 230000003287 optical effect Effects 0.000 description 7
- CPBQJMYROZQQJC-UHFFFAOYSA-N helium neon Chemical compound [He].[Ne] CPBQJMYROZQQJC-UHFFFAOYSA-N 0.000 description 6
- XKRFYHLGVUSROY-UHFFFAOYSA-N argon Substances [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 3
- 229910052786 argon Inorganic materials 0.000 description 3
- -1 argon ion Chemical class 0.000 description 3
- 239000007850 fluorescent dye Substances 0.000 description 3
- 229910052743 krypton Inorganic materials 0.000 description 3
- DNNSSWSSYDEUBZ-UHFFFAOYSA-N krypton atom Chemical compound [Kr] DNNSSWSSYDEUBZ-UHFFFAOYSA-N 0.000 description 3
- 108010004729 Phycoerythrin Proteins 0.000 description 2
- 108010004469 allophycocyanin Proteins 0.000 description 2
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- XJMOSONTPMZWPB-UHFFFAOYSA-M propidium iodide Chemical compound [I-].[I-].C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CCC[N+](C)(CC)CC)=C1C1=CC=CC=C1 XJMOSONTPMZWPB-UHFFFAOYSA-M 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- MPLHNVLQVRSVEE-UHFFFAOYSA-N texas red Chemical compound [O-]S(=O)(=O)C1=CC(S(Cl)(=O)=O)=CC=C1C(C1=CC=2CCCN3CCCC(C=23)=C1O1)=C2C1=C(CCC1)C3=[N+]1CCCC3=C2 MPLHNVLQVRSVEE-UHFFFAOYSA-N 0.000 description 2
- FWBHETKCLVMNFS-UHFFFAOYSA-N 4',6-Diamino-2-phenylindol Chemical compound C1=CC(C(=N)N)=CC=C1C1=CC2=CC=C(C(N)=N)C=C2N1 FWBHETKCLVMNFS-UHFFFAOYSA-N 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- UYRDHEJRPVSJFM-VSWVFQEASA-N [(1s,3r)-3-hydroxy-4-[(3e,5e,7e,9e,11z)-11-[4-[(e)-2-[(1r,3s,6s)-3-hydroxy-1,5,5-trimethyl-7-oxabicyclo[4.1.0]heptan-6-yl]ethenyl]-5-oxofuran-2-ylidene]-3,10-dimethylundeca-1,3,5,7,9-pentaenylidene]-3,5,5-trimethylcyclohexyl] acetate Chemical compound C[C@@]1(O)C[C@@H](OC(=O)C)CC(C)(C)C1=C=C\C(C)=C\C=C\C=C\C=C(/C)\C=C/1C=C(\C=C\[C@]23[C@@](O2)(C)C[C@@H](O)CC3(C)C)C(=O)O\1 UYRDHEJRPVSJFM-VSWVFQEASA-N 0.000 description 1
- 229930002875 chlorophyll Natural products 0.000 description 1
- 235000019804 chlorophyll Nutrition 0.000 description 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 238000002866 fluorescence resonance energy transfer Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000138 intercalating agent Substances 0.000 description 1
- 239000011325 microbead Substances 0.000 description 1
- VYNDHICBIRRPFP-UHFFFAOYSA-N pacific blue Chemical compound FC1=C(O)C(F)=C2OC(=O)C(C(=O)O)=CC2=C1 VYNDHICBIRRPFP-UHFFFAOYSA-N 0.000 description 1
- UTIQDNPUHSAVDN-UHFFFAOYSA-N peridinin Natural products CC(=O)OC1CC(C)(C)C(=C=CC(=CC=CC=CC=C2/OC(=O)C(=C2)C=CC34OC3(C)CC(O)CC4(C)C)C)C(C)(O)C1 UTIQDNPUHSAVDN-UHFFFAOYSA-N 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Images
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009140043A JP5321260B2 (ja) | 2009-06-11 | 2009-06-11 | 光学的測定装置、並びにフローサイトメーター及び光学的測定方法 |
| US12/792,271 US8350231B2 (en) | 2009-06-11 | 2010-06-02 | Optical measurement apparatus, flow site meter and optical measurement method |
| CN2010101982220A CN101923046B (zh) | 2009-06-11 | 2010-06-04 | 光学测量装置、流量现场测量计及光学测量方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009140043A JP5321260B2 (ja) | 2009-06-11 | 2009-06-11 | 光学的測定装置、並びにフローサイトメーター及び光学的測定方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010286341A JP2010286341A (ja) | 2010-12-24 |
| JP2010286341A5 true JP2010286341A5 (https=) | 2012-03-22 |
| JP5321260B2 JP5321260B2 (ja) | 2013-10-23 |
Family
ID=43305625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009140043A Expired - Fee Related JP5321260B2 (ja) | 2009-06-11 | 2009-06-11 | 光学的測定装置、並びにフローサイトメーター及び光学的測定方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US8350231B2 (https=) |
| JP (1) | JP5321260B2 (https=) |
| CN (1) | CN101923046B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2702133B1 (en) | 2011-04-29 | 2017-08-23 | Becton Dickinson and Company | Cell sorter system and method |
| JP2013040782A (ja) * | 2011-08-11 | 2013-02-28 | Sony Corp | 光学的測定装置及びチップ寿命判定方法 |
| JP5924077B2 (ja) | 2012-03-30 | 2016-05-25 | ソニー株式会社 | 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法 |
| WO2013145905A1 (ja) | 2012-03-30 | 2013-10-03 | ソニー株式会社 | 微小粒子分取装置及び該装置における流体ストリーム最適化方法 |
| US9029724B2 (en) | 2012-03-30 | 2015-05-12 | Sony Corporation | Microparticle sorting device and method for controlling position in microparticle sorting device |
| WO2014115409A1 (ja) | 2013-01-28 | 2014-07-31 | ソニー株式会社 | 微小粒子分取装置、微小粒子分取方法及びプログラム |
| US9597229B2 (en) | 2013-03-15 | 2017-03-21 | Abbott Medical Optics Inc. | Phacoemulsification flow rate detection system and method |
| US9857284B1 (en) * | 2013-07-15 | 2018-01-02 | Stratedigm, Inc. | Method and apparatus for detection and measurement of particles with a wide dynamic range of measurement |
| EP3035030B1 (en) | 2013-10-16 | 2019-07-10 | Sony Corporation | Particle fractionation device, particle fractionation method, and program |
| JP2015094737A (ja) * | 2013-11-14 | 2015-05-18 | ソニー株式会社 | 光照射装置、粒子分析装置および光照射方法 |
| JP6465036B2 (ja) | 2014-02-13 | 2019-02-06 | ソニー株式会社 | 粒子分取装置、粒子分取方法、プログラム及び粒子分取システム |
| CN106574891A (zh) * | 2014-08-06 | 2017-04-19 | 贝克曼考尔特公司 | 使用流式细胞仪评价多峰事件 |
| CN104198002A (zh) * | 2014-08-28 | 2014-12-10 | 内蒙古大学 | 一种基于红外光幕的非接触原奶流量计 |
| JP6657625B2 (ja) | 2014-09-05 | 2020-03-04 | ソニー株式会社 | 液滴分取装置、液滴分取方法及びプログラム |
| JP2016095221A (ja) * | 2014-11-14 | 2016-05-26 | ソニー株式会社 | 粒子分析装置、粒子分析方法 |
| US10302545B2 (en) | 2015-10-05 | 2019-05-28 | Becton, Dickinson And Company | Automated drop delay calculation |
| WO2017068822A1 (ja) | 2015-10-19 | 2017-04-27 | ソニー株式会社 | 画像処理装置、微小粒子分取装置及び画像処理方法 |
| US10024780B2 (en) | 2015-12-18 | 2018-07-17 | Abbott Laboratories (Diagnostics Division) | Methods for detecting events in a flow cytometer |
| JP6654059B2 (ja) * | 2016-02-18 | 2020-02-26 | アズビル株式会社 | 粒子検出システム及び粒子の検出方法 |
| JP2020051936A (ja) | 2018-09-27 | 2020-04-02 | ソニー株式会社 | 微小粒子測定装置及び微小粒子測定方法 |
| US12360041B2 (en) * | 2020-09-10 | 2025-07-15 | Becton, Dickinson And Company | Laser light propagation systems for irradiating a sample in a flow stream and methods for using same |
| JP2023549475A (ja) * | 2020-10-20 | 2023-11-27 | ベクトン・ディキンソン・アンド・カンパニー | 傾斜ビーム成形光学部品を含むフローサイトメータ、及びフローサイトメータを使用する方法 |
| CN113476739B (zh) * | 2021-06-07 | 2022-11-08 | 浙江迪远医疗器械有限公司 | 具有检测装置的血液泵 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4573796A (en) * | 1984-01-06 | 1986-03-04 | The United States Of America As Represented By The United States Department Of Energy | Apparatus for eliminating background interference in fluorescence measurements |
| JPH0785054B2 (ja) * | 1990-07-04 | 1995-09-13 | リオン株式会社 | 微粒子計 |
| JP3102935B2 (ja) * | 1991-11-20 | 2000-10-23 | シスメックス株式会社 | イメージングフローサイトメータ |
| JPH0792077A (ja) * | 1993-09-24 | 1995-04-07 | Canon Inc | 粒子解析装置 |
| US5827660A (en) * | 1996-08-09 | 1998-10-27 | University Of Massachusetts | Caged fluorochrome-labeled probes and subtraction of autoflourescence background |
| JP2003139696A (ja) * | 2001-10-30 | 2003-05-14 | Toshiba Corp | 油劣化診断装置 |
| GB2383127B (en) * | 2001-12-12 | 2004-10-20 | Proimmune Ltd | Device and method for investigating analytes in liquid suspension or solution |
| US6897954B2 (en) * | 2002-12-20 | 2005-05-24 | Becton, Dickinson And Company | Instrument setup system for a fluorescence analyzer |
| JP2005001866A (ja) | 2003-06-13 | 2005-01-06 | Canon Electronics Inc | シート排出装置及びプリンタ装置 |
| CN103454192B (zh) * | 2003-07-02 | 2016-08-24 | 泰尔茂比司特公司 | 一种用于提取端口中细胞分离室光学表面的光学单元 |
| US7692773B2 (en) * | 2003-08-05 | 2010-04-06 | Luminex Corporation | Light emitting diode based measurement systems |
| JP3931875B2 (ja) * | 2003-10-29 | 2007-06-20 | 財団法人雑賀技術研究所 | 分光光度計 |
| EP1704402B1 (en) * | 2004-01-14 | 2016-05-11 | Luminex Corporation | Methods and systems for dynamic range expansion |
| US20060219873A1 (en) * | 2005-04-01 | 2006-10-05 | Martin Steven M | Detection system for a flow cytometer |
| JP4758723B2 (ja) * | 2005-10-03 | 2011-08-31 | シスメックス株式会社 | 粒子分析装置及び粒子分析方法 |
| CN1959373A (zh) * | 2006-11-03 | 2007-05-09 | 刘文清 | 光学流速颗粒物浓度测量方法及装置 |
| WO2008118353A1 (en) * | 2007-03-23 | 2008-10-02 | Beckman Coulter, Inc. | Multi-gain adaptive linear processing and gated digital system for use in flow cytometry |
| CN101082559B (zh) * | 2007-06-27 | 2010-11-03 | 上海理工大学 | 透过率相关频谱法颗粒测量方法及其装置 |
| JP4509154B2 (ja) * | 2007-09-04 | 2010-07-21 | ソニー株式会社 | 光照射装置、微粒子解析装置及び光照射方法 |
| WO2009039165A1 (en) * | 2007-09-17 | 2009-03-26 | Luminex Corporation | Systems, storage mediums, and methods for identifying particles in flow |
-
2009
- 2009-06-11 JP JP2009140043A patent/JP5321260B2/ja not_active Expired - Fee Related
-
2010
- 2010-06-02 US US12/792,271 patent/US8350231B2/en active Active
- 2010-06-04 CN CN2010101982220A patent/CN101923046B/zh not_active Expired - Fee Related
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