|
US7219016B2
(en)
|
2001-04-20 |
2007-05-15 |
Yale University |
Systems and methods for automated analysis of cells and tissues
|
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
|
EP1392359B2
(en)
|
2001-05-11 |
2013-03-13 |
Ludwig Institute for Cancer Research Ltd. |
Specific binding proteins and uses thereof
|
|
CN101501211A
(zh)
|
2004-03-31 |
2009-08-05 |
综合医院公司 |
测定癌症对表皮生长因子受体靶向性治疗反应性的方法
|
|
EP1766068A4
(en)
|
2004-06-04 |
2010-03-03 |
Genentech Inc |
EGFR Mutations
|
|
TW200617396A
(en)
*
|
2004-10-06 |
2006-06-01 |
Astrazeneca Ab |
Method
|
|
WO2006044994A2
(en)
*
|
2004-10-18 |
2006-04-27 |
Brandeis University |
Primers, probes and methods for nucleic acid amplification
|
|
WO2006070667A1
(ja)
*
|
2004-12-28 |
2006-07-06 |
Takara Bio Inc. |
Ｅｇｆｒ遺伝子変異の検出法ならびに検出キット
|
|
ES2364495T3
(es)
|
2005-02-03 |
2011-09-05 |
The General Hospital Corporation |
Método para tratar cáncer resistente a gefitinib.
|
|
CN101193905B
(zh)
|
2005-02-11 |
2014-06-25 |
纪念斯隆-凯特林癌症中心 |
用于检测抗药egfr突变体的方法和组合物
|
|
MX2007009963A
(es)
|
2005-02-24 |
2007-09-26 |
Amgen Inc |
Mutaciones del receptor del factor de crecimiento epidermico.
|
|
GB0506670D0
(en)
*
|
2005-04-01 |
2005-05-11 |
Astrazeneca Ab |
Method
|
|
GB2424886A
(en)
*
|
2005-04-04 |
2006-10-11 |
Dxs Ltd |
Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
|
|
JP2008538282A
(ja)
|
2005-04-05 |
2008-10-23 |
セルポイント ダイアグノスティクス， インコーポレイテッド |
装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法
|
|
RU2007134908A
(ru)
*
|
2005-04-14 |
2009-05-20 |
Вайет (Us) |
Применение ингибитора активности киназы рецептора эпидермального фактора роста для лечения пациентов, невосприимчивых к гефитинибу
|
|
PL1913157T5
(pl)
*
|
2005-06-28 |
2017-09-29 |
Genentech Inc |
Mutacje EGFR i KRAS do prognozowania reakcji pacjenta na leczenie inhibitorem EGFR
|
|
EP1931798A1
(en)
*
|
2005-10-05 |
2008-06-18 |
AstraZeneca UK Limited |
Method to predict or monitor the response of a patient to an erbb receptor drug
|
|
JP2009514870A
(ja)
|
2005-11-04 |
2009-04-09 |
ワイス |
ｍＴＯＲインヒビター、ハーセプチン、および／またはＨＫＩ−２７２の抗悪性腫瘍性組み合わせ
|
|
CA2833706C
(en)
*
|
2005-11-11 |
2014-10-21 |
Boehringer Ingelheim International Gmbh |
Quinazoline derivatives for the treatment of cancer diseases
|
|
PL1948180T3
(pl)
*
|
2005-11-11 |
2013-09-30 |
Boehringer Ingelheim Int |
Terapia skojarzona raka polegająca na podawaniu inhibitorów EGFR/HER2
|
|
WO2007099852A1
(ja)
*
|
2006-02-23 |
2007-09-07 |
National University Corporation Kanazawa University |
固形癌のチロシンキナーゼ阻害剤に対する感受性を検査する方法及び検査キット
|
|
US7906342B2
(en)
|
2006-03-31 |
2011-03-15 |
Biodesix, Inc. |
Monitoring treatment of cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples
|
|
US7867775B2
(en)
*
|
2006-03-31 |
2011-01-11 |
Biodesix, Inc. |
Selection of head and neck cancer patients for treatment with drugs targeting EGFR pathway
|
|
US7736905B2
(en)
|
2006-03-31 |
2010-06-15 |
Biodesix, Inc. |
Method and system for determining whether a drug will be effective on a patient with a disease
|
|
WO2007130677A2
(en)
|
2006-05-05 |
2007-11-15 |
Yale University |
Use of subcellular localization profiles as prognostic or predictive indicators
|
|
US8768629B2
(en)
*
|
2009-02-11 |
2014-07-01 |
Caris Mpi, Inc. |
Molecular profiling of tumors
|
|
CN103424541B
(zh)
*
|
2006-05-18 |
2018-01-30 |
分子压型学会股份有限公司 |
确定针对病状的个性化医疗介入的系统和方法
|
|
US12366585B2
(en)
|
2006-05-18 |
2025-07-22 |
Caris Mpi, Inc. |
Molecular profiling of tumors
|
|
WO2007147079A2
(en)
|
2006-06-14 |
2007-12-21 |
Living Microsystems, Inc. |
Rare cell analysis using sample splitting and dna tags
|
|
EP2589668A1
(en)
|
2006-06-14 |
2013-05-08 |
Verinata Health, Inc |
Rare cell analysis using sample splitting and DNA tags
|
|
US7709222B2
(en)
*
|
2006-07-13 |
2010-05-04 |
Yale University |
Methods for making cancer prognoses based on subcellular localization of biomarkers
|
|
AU2007299080B2
(en)
*
|
2006-09-18 |
2013-04-18 |
Boehringer Ingelheim International Gmbh |
Method for treating cancer harboring EGFR mutations
|
|
WO2008038812A1
(en)
*
|
2006-09-28 |
2008-04-03 |
Shimadzu Corporation |
Method of preparing sample for matrix-assisted laser desorption ionization mass spectrometry and matrix-assisted laser desorption ionization mass spectrometry
|
|
JP4795203B2
(ja)
*
|
2006-11-13 |
2011-10-19 |
シスメックス株式会社 |
アンスラサイクリン系抗癌剤の感受性判定方法及びそのシステム
|
|
US9090693B2
(en)
|
2007-01-25 |
2015-07-28 |
Dana-Farber Cancer Institute |
Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease
|
|
SG178789A1
(en)
*
|
2007-02-16 |
2012-03-29 |
Merrimack Pharmaceuticals Inc |
Antibodies against erbb3 and uses thereof
|
|
ES2426814T3
(es)
*
|
2007-03-13 |
2013-10-25 |
Amgen Inc. |
Mutaciones de K-ras y B-raf y terapia con anticuerpos anti-EGFr
|
|
AR065687A1
(es)
|
2007-03-13 |
2009-06-24 |
Amgen Inc |
Metodo para determinar la presencia o no de una mutacion k-ras y terapia con anticuerpos anti-egfr
|
|
ES2542152T3
(es)
|
2007-03-15 |
2015-07-31 |
Ludwig Institute For Cancer Research Ltd. |
Método de tratamiento que emplea anticuerpos de EGFR e inhibidores de Src y formulaciones relacionadas
|
|
US8642067B2
(en)
|
2007-04-02 |
2014-02-04 |
Allergen, Inc. |
Methods and compositions for intraocular administration to treat ocular conditions
|
|
US8999634B2
(en)
*
|
2007-04-27 |
2015-04-07 |
Quest Diagnostics Investments Incorporated |
Nucleic acid detection combining amplification with fragmentation
|
|
NZ581201A
(en)
|
2007-05-11 |
2012-05-25 |
Enzon Pharmaceuticals Inc |
Rna antagonist compounds for the modulation of her3
|
|
WO2009005715A1
(en)
*
|
2007-06-29 |
2009-01-08 |
Yale University |
Methods for a predictive diagnostic test for tamoxifen
|
|
CN108424454B
(zh)
|
2007-08-14 |
2022-05-31 |
路德维格癌症研究所有限公司 |
靶向egf受体的单克隆抗体175及其衍生物和用途
|
|
US8022216B2
(en)
|
2007-10-17 |
2011-09-20 |
Wyeth Llc |
Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
|
|
EP2245199B1
(en)
|
2008-02-01 |
2013-11-13 |
The General Hospital Corporation |
Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions
|
|
HUE029914T2
(en)
*
|
2008-04-03 |
2017-04-28 |
Cb Biotechnologies Inc |
Amplicon-saving multiplex polymerase chain reaction for amplification of multiple targets
|
|
US8137919B2
(en)
*
|
2008-04-10 |
2012-03-20 |
Montefiore Medical Center |
Method of determining the sensitivity of cancer cells to EGFR inhibitors including cetuximab, panitumumab and erlotinib
|
|
CN101445829B
(zh)
*
|
2008-04-23 |
2013-06-05 |
广州益善生物技术有限公司 |
Egfr基因突变位点的检测探针、液相芯片及其检测方法
|
|
ES2692769T3
(es)
|
2008-06-17 |
2018-12-05 |
Wyeth Llc |
Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina
|
|
CN105147713A
(zh)
|
2008-08-04 |
2015-12-16 |
惠氏有限责任公司 |
4-苯胺基-3-氰基喹啉和卡培他滨的抗肿瘤组合
|
|
UA104868C2
(uk)
*
|
2008-08-15 |
2014-03-25 |
Меррімак Фармасьютікалз, Інк. |
Спосіб лікування пацієнта, що має неопластичну пухлину, відповідно до спрогнозованої реакції
|
|
US8583380B2
(en)
|
2008-09-05 |
2013-11-12 |
Aueon, Inc. |
Methods for stratifying and annotating cancer drug treatment options
|
|
US9764322B2
(en)
|
2008-09-23 |
2017-09-19 |
Bio-Rad Laboratories, Inc. |
System for generating droplets with pressure monitoring
|
|
WO2011120024A1
(en)
|
2010-03-25 |
2011-09-29 |
Quantalife, Inc. |
Droplet generation for droplet-based assays
|
|
US8633015B2
(en)
|
2008-09-23 |
2014-01-21 |
Bio-Rad Laboratories, Inc. |
Flow-based thermocycling system with thermoelectric cooler
|
|
US11130128B2
(en)
|
2008-09-23 |
2021-09-28 |
Bio-Rad Laboratories, Inc. |
Detection method for a target nucleic acid
|
|
US9492797B2
(en)
|
2008-09-23 |
2016-11-15 |
Bio-Rad Laboratories, Inc. |
System for detection of spaced droplets
|
|
US9156010B2
(en)
|
2008-09-23 |
2015-10-13 |
Bio-Rad Laboratories, Inc. |
Droplet-based assay system
|
|
WO2011120006A1
(en)
|
2010-03-25 |
2011-09-29 |
Auantalife, Inc. A Delaware Corporation |
Detection system for droplet-based assays
|
|
US9417190B2
(en)
|
2008-09-23 |
2016-08-16 |
Bio-Rad Laboratories, Inc. |
Calibrations and controls for droplet-based assays
|
|
CA2738578C
(en)
|
2008-09-23 |
2021-05-04 |
Quantalife, Inc. |
Droplet-based assay system
|
|
US9132394B2
(en)
|
2008-09-23 |
2015-09-15 |
Bio-Rad Laboratories, Inc. |
System for detection of spaced droplets
|
|
US9399215B2
(en)
|
2012-04-13 |
2016-07-26 |
Bio-Rad Laboratories, Inc. |
Sample holder with a well having a wicking promoter
|
|
US8709762B2
(en)
|
2010-03-02 |
2014-04-29 |
Bio-Rad Laboratories, Inc. |
System for hot-start amplification via a multiple emulsion
|
|
US9598725B2
(en)
|
2010-03-02 |
2017-03-21 |
Bio-Rad Laboratories, Inc. |
Emulsion chemistry for encapsulated droplets
|
|
US12162008B2
(en)
|
2008-09-23 |
2024-12-10 |
Bio-Rad Laboratories, Inc. |
Partition-based method of analysis
|
|
US8951939B2
(en)
|
2011-07-12 |
2015-02-10 |
Bio-Rad Laboratories, Inc. |
Digital assays with multiplexed detection of two or more targets in the same optical channel
|
|
US12090480B2
(en)
|
2008-09-23 |
2024-09-17 |
Bio-Rad Laboratories, Inc. |
Partition-based method of analysis
|
|
US10512910B2
(en)
|
2008-09-23 |
2019-12-24 |
Bio-Rad Laboratories, Inc. |
Droplet-based analysis method
|
|
CN102232117A
(zh)
*
|
2008-10-14 |
2011-11-02 |
卡里斯Mpi公司 |
描绘肿瘤类型生物标志模式和特征集的基因靶和基因表达的蛋白靶
|
|
IL313131A
(en)
*
|
2009-02-11 |
2024-07-01 |
Caris Mpi Inc |
Molecular characterization of tumors
|
|
WO2010101916A1
(en)
*
|
2009-03-02 |
2010-09-10 |
Trackfive Diagnostics Inc |
Methods for predicting cancer response to egfr inhibitors
|
|
SG174382A1
(en)
|
2009-04-06 |
2011-11-28 |
Wyeth Llc |
Treatment regimen utilizing neratinib for breast cancer
|
|
PL2451445T3
(pl)
|
2009-07-06 |
2019-09-30 |
Boehringer Ingelheim International Gmbh |
Sposób suszenia BIBW2992, jego soli i stałych preparatów farmaceutycznych zawierających tę substancję czynną
|
|
EP2473618B1
(en)
|
2009-09-02 |
2015-03-04 |
Bio-Rad Laboratories, Inc. |
System for mixing fluids by coalescence of multiple emulsions
|
|
EP2475989A4
(en)
|
2009-09-09 |
2013-02-27 |
Gen Hospital Corp |
USE OF MICROVESICLES IN THE ANALYSIS OF KRAS MUTATIONS
|
|
WO2011031982A1
(en)
*
|
2009-09-10 |
2011-03-17 |
Myriad Genetics, Inc. |
Methods and compositions for predicting cancer therapy response
|
|
US8323883B1
(en)
|
2009-10-09 |
2012-12-04 |
Cold Spring Harbor Laboratory |
Methods of assessing therapeutic benefits of patients having cancers resistant to epidermal growth factor receptor kinase inhibitors
|
|
US7947653B1
(en)
|
2009-10-09 |
2011-05-24 |
Cold Spring Harbor Laboratory |
Methods for treating epidermal growth factor receptor tyrosine kinase inhibitor-resistant cancers
|
|
CN102724962B
(zh)
|
2009-11-09 |
2017-05-17 |
惠氏有限责任公司 |
包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途
|
|
US20120316187A1
(en)
|
2009-11-13 |
2012-12-13 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
|
US9034658B2
(en)
|
2009-11-23 |
2015-05-19 |
The General Hospital Corporation |
Microfluidic devices for the capture of biological sample components
|
|
CA2781886A1
(en)
*
|
2009-12-11 |
2011-06-16 |
Dignity Health |
Pi3k/akt pathway subgroups in cancer: methods of using biomarkers for diagnosis and therapy
|
|
US10731221B2
(en)
|
2009-12-11 |
2020-08-04 |
Dignity Health |
Diagnosing IDH1 related subgroups and treatment of cancer
|
|
US20110224205A1
(en)
*
|
2010-02-11 |
2011-09-15 |
National Taiwan University |
Use of curcumin or its analogues in cancer therapy utilizing epidermal growth factor receptor tyrosine kinase inhibitor
|
|
CA2792327C
(en)
|
2010-03-11 |
2019-09-24 |
Merrimack Pharmaceuticals, Inc. |
Use of erbb3 inhibitors in the treatment of triple negative and basal-like breast cancers
|
|
WO2011113942A2
(en)
*
|
2010-03-18 |
2011-09-22 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Method for predicting the responsiveness to chemotherapy
|
|
JP6155419B2
(ja)
|
2010-03-25 |
2017-07-05 |
バイオ−ラッド・ラボラトリーズ・インコーポレーテッド |
検出用の液滴輸送システム
|
|
CN102234683B
(zh)
*
|
2010-04-23 |
2013-07-17 |
广州益善生物技术有限公司 |
一种egfr基因突变检测液相芯片
|
|
CN101858909B
(zh)
*
|
2010-05-28 |
2013-07-03 |
广州瑞博奥生物科技有限公司 |
检测磷酸化表皮生长因子受体的试剂盒及其制备方法
|
|
RU2565550C2
(ru)
|
2010-09-24 |
2015-10-20 |
Те Борд Оф Трастиз Оф Те Лилэнд Стэнфорд Джуниор Юниверсити |
Прямой захват, амплификация и секвенирование днк-мишени с использованием иммобилизированных праймеров
|
|
CN103080314B
(zh)
*
|
2010-09-30 |
2016-04-13 |
Lsip基金运营联合公司 |
显性突变基因表达抑制剂
|
|
CN105399831A
(zh)
|
2010-10-29 |
2016-03-16 |
伊缪诺金公司 |
非拮抗性egfr结合分子及其免疫偶联物
|
|
CN103298489A
(zh)
|
2010-10-29 |
2013-09-11 |
伊缪诺金公司 |
新型egfr结合分子及其免疫偶联物
|
|
CN103429331B
(zh)
|
2010-11-01 |
2016-09-28 |
伯乐生命医学产品有限公司 |
用于形成乳液的系统
|
|
WO2012065071A2
(en)
*
|
2010-11-12 |
2012-05-18 |
The Broad Institute Of Mit And Harvard |
Methods of predicting response to egfr antibody therapy
|
|
WO2012065705A1
(en)
|
2010-11-19 |
2012-05-24 |
Roche Diagnostics Gmbh |
Novel complex mutation in the epidermal growth factor receptor kinase domain
|
|
US20120164641A1
(en)
|
2010-12-22 |
2012-06-28 |
Roche Molecular Systems, Inc. |
Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene
|
|
CN102140518B
(zh)
*
|
2011-01-18 |
2013-02-06 |
杭州迪安医学检验中心有限公司 |
肺癌相关表皮生长因子受体egfr外显子突变定量检测试剂盒及方法
|
|
WO2012103442A2
(en)
|
2011-01-28 |
2012-08-02 |
The Broad Institute, Inc. |
Paired end bead amplification and high throughput sequencing
|
|
WO2012102829A1
(en)
|
2011-01-28 |
2012-08-02 |
Biodesix, Inc. |
Predictive test for selection of metastatic breast cancer patients for hormonal and combination therapy
|
|
EP2675916B1
(en)
|
2011-02-15 |
2016-08-24 |
Leica Biosystems Newcastle Limited |
METHOD FOR LOCALIZED IN SITU DETECTION OF mRNA
|
|
US9556473B2
(en)
|
2011-02-15 |
2017-01-31 |
Leica Biosystems Newcastle Ltd |
Methods for identifying nucleic acid sequences
|
|
US12097495B2
(en)
|
2011-02-18 |
2024-09-24 |
Bio-Rad Laboratories, Inc. |
Methods and compositions for detecting genetic material
|
|
EP2492688A1
(en)
|
2011-02-23 |
2012-08-29 |
Pangaea Biotech, S.A. |
Molecular biomarkers for predicting response to antitumor treatment in lung cancer
|
|
WO2012129145A1
(en)
|
2011-03-18 |
2012-09-27 |
OSI Pharmaceuticals, LLC |
Nscle combination therapy
|
|
AU2012231098B2
(en)
|
2011-03-18 |
2016-09-29 |
Bio-Rad Laboratories, Inc. |
Multiplexed digital assays with combinatorial use of signals
|
|
US9347059B2
(en)
|
2011-04-25 |
2016-05-24 |
Bio-Rad Laboratories, Inc. |
Methods and compositions for nucleic acid analysis
|
|
JP5930825B2
(ja)
*
|
2011-05-06 |
2016-06-08 |
アークレイ株式会社 |
Ｅｇｆｒエクソン１９多型検出試験用試薬キット及びその用途
|
|
EP2737089B1
(en)
|
2011-07-29 |
2017-09-06 |
Bio-rad Laboratories, Inc. |
Library characterization by digital assay
|
|
EP2739587B1
(en)
|
2011-08-01 |
2020-05-27 |
Denovo Sciences |
Cell capture system
|
|
US9174216B2
(en)
|
2013-03-13 |
2015-11-03 |
DeNovo Science, Inc. |
System for capturing and analyzing cells
|
|
US9404864B2
(en)
|
2013-03-13 |
2016-08-02 |
Denovo Sciences, Inc. |
System for imaging captured cells
|
|
US10466160B2
(en)
|
2011-08-01 |
2019-11-05 |
Celsee Diagnostics, Inc. |
System and method for retrieving and analyzing particles
|
|
US10364464B2
(en)
|
2011-08-08 |
2019-07-30 |
The Broad Institute, Inc. |
Compositions and methods for co-amplifying subsequences of a nucleic acid fragment sequence
|
|
US9738935B2
(en)
|
2011-11-10 |
2017-08-22 |
Roche Molecular Systems, Inc. |
Complex mutations in the epidermal growth factor receptor kinase domain
|
|
US9233171B2
(en)
|
2011-11-21 |
2016-01-12 |
Immunogen, Inc. |
Method of treatment of tumors that are resistant to EGFR antibody therapies by EGFR antibody cytotoxic agent conjugate
|
|
US9260714B2
(en)
|
2011-12-02 |
2016-02-16 |
Roche Molecular Systems, Inc. |
Suppression of non-specific amplification with high-homology oligonucleotides
|
|
KR101963230B1
(ko)
|
2011-12-26 |
2019-03-29 |
삼성전자주식회사 |
복수개의 단일 항체를 포함하는 단백질 복합체
|
|
EP2653558B1
(en)
|
2012-04-18 |
2015-10-07 |
Roche Diagniostics GmbH |
A method of detecting nucleic acid targets using a statistical classifier
|
|
CN102732636B
(zh)
*
|
2012-07-17 |
2014-01-15 |
海南医学院 |
一种检测肿瘤细胞egfr基因突变的芯片
|
|
CN102851375B
(zh)
*
|
2012-09-11 |
2014-02-19 |
上海源奇生物医药科技有限公司 |
检测egfr基因突变的引物、探针及其试剂盒和使用方法
|
|
KR101911438B1
(ko)
*
|
2012-10-31 |
2018-10-24 |
삼성전자주식회사 |
이중 특이 항원 결합 단백질 복합체 및 이중 특이 항체의 제조 방법
|
|
US20140341884A1
(en)
*
|
2012-12-04 |
2014-11-20 |
Roche Molecular Systems, Inc. |
Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain
|
|
US9752181B2
(en)
|
2013-01-26 |
2017-09-05 |
Denovo Sciences, Inc. |
System and method for capturing and analyzing cells
|
|
CN105209456B
(zh)
|
2013-03-06 |
2018-05-08 |
阿斯利康(瑞典)有限公司 |
表皮生长因子受体的活化突变形式的喹唑啉抑制剂
|
|
US20140287417A1
(en)
|
2013-03-08 |
2014-09-25 |
Roche Molecular Systems, Inc. |
EGFR Blood Monitoring
|
|
ES2662598T3
(es)
|
2013-03-08 |
2018-04-09 |
F. Hoffmann-La Roche Ag |
Análisis de sangre para la detección de mutaciones de EGFR
|
|
US9707562B2
(en)
|
2013-03-13 |
2017-07-18 |
Denovo Sciences, Inc. |
System for capturing and analyzing cells
|
|
US10391490B2
(en)
|
2013-05-31 |
2019-08-27 |
Celsee Diagnostics, Inc. |
System and method for isolating and analyzing cells
|
|
US9856535B2
(en)
|
2013-05-31 |
2018-01-02 |
Denovo Sciences, Inc. |
System for isolating cells
|
|
CN103333963A
(zh)
*
|
2013-06-09 |
2013-10-02 |
中国人民解放军第四军医大学 |
Egfr突变检测引物组及其用途
|
|
JP6463675B2
(ja)
*
|
2013-06-19 |
2019-02-06 |
学校法人 久留米大学 |
上皮成長因子受容体チロシンキナーゼ阻害薬の治療効果を予測する方法
|
|
EP3019491A4
(en)
|
2013-07-09 |
2016-12-21 |
Dana Farber Cancer Inst Inc |
KINASEHEMMER FOR THE TREATMENT OF DISEASES
|
|
EP3087394A2
(en)
|
2013-12-27 |
2016-11-02 |
Merrimack Pharmaceuticals, Inc. |
Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies
|
|
US9242965B2
(en)
|
2013-12-31 |
2016-01-26 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
|
|
CN103923975B
(zh)
*
|
2014-01-27 |
2016-01-20 |
上海涌泰生物医药科技有限公司 |
一种检测egfr基因外显子19缺失突变的试剂盒和方法
|
|
US9211314B2
(en)
|
2014-04-04 |
2015-12-15 |
Biodesix, Inc. |
Treatment selection for lung cancer patients using mass spectrum of blood-based sample
|
|
US11015225B2
(en)
*
|
2014-07-28 |
2021-05-25 |
Alberto Bardelli |
Method of treating cancer based on identifying mutations in the extracellular domain III of epidermal growth factor receptor gene
|
|
WO2016055380A1
(en)
|
2014-10-09 |
2016-04-14 |
Roche Diagnostics Gmbh |
Mutations in the epidermal growth factor receptor kinase domain
|
|
KR101692044B1
(ko)
*
|
2014-12-05 |
2017-01-04 |
사회복지법인 삼성생명공익재단 |
교모세포종에서 표피 성장인자 수용체 억제제의 치료 효과를 예측하는 방법
|
|
US12595297B2
(en)
*
|
2015-05-12 |
2026-04-07 |
In3Bio Ltd. |
Methods and compositions for inhibition of EGF/EGFR pathway in combination with tyrosine kinase inhibitors
|
|
US10184006B2
(en)
|
2015-06-04 |
2019-01-22 |
Merrimack Pharmaceuticals, Inc. |
Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
|
|
AU2016350701B2
(en)
|
2015-11-02 |
2021-08-19 |
Five Prime Therapeutics, Inc. |
CD80 extracellular domain polypeptides and their use in cancer treatment
|
|
CA3014252A1
(en)
*
|
2016-02-12 |
2017-08-17 |
Nantomics, Llc |
High-throughput identification of patient-specific neoepitopes as therapeutic targets for cancer immunotherapies
|
|
CN105624309B
(zh)
*
|
2016-02-23 |
2020-04-21 |
深圳华大生命科学研究院 |
检测EGFR和/或K-ras基因突变的引物、探针及试剂盒
|
|
CN105866217B
(zh)
*
|
2016-03-21 |
2018-04-10 |
杭州市红十字会医院 |
三尖杉酯碱癌症治疗效果检测装置及方法
|
|
CN109983135A
(zh)
*
|
2016-05-25 |
2019-07-05 |
建喾立嗣股份公司 |
表皮细胞生长因子受体基因突变检测用组合物及包含其的试剂盒
|
|
WO2018195339A1
(en)
|
2017-04-19 |
2018-10-25 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
CN109937603B
(zh)
*
|
2017-05-03 |
2021-12-28 |
华为技术有限公司 |
基于竞争的传输方法和设备
|
|
US10299039B2
(en)
|
2017-06-02 |
2019-05-21 |
Apple Inc. |
Audio adaptation to room
|
|
WO2019046307A1
(en)
|
2017-08-29 |
2019-03-07 |
Celsee Diagnostics, Inc. |
SYSTEM AND METHOD FOR ISOLATING AND ANALYZING CELLS
|
|
WO2019074920A1
(en)
*
|
2017-10-10 |
2019-04-18 |
Oncocyte Corporation |
METHODS AND COMPOSITIONS FOR THE DETECTION AND DIAGNOSIS OF BREAST CANCER
|
|
CN109722476A
(zh)
*
|
2017-10-31 |
2019-05-07 |
北京雅康博生物科技有限公司 |
用于检测egfr基因2237-2257位突变的引物、探针及试剂盒
|
|
JP7273421B2
(ja)
|
2018-02-21 |
2023-05-15 |
ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
|
|
US12577286B2
(en)
*
|
2018-05-01 |
2026-03-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors which recognize mutated EGFR
|
|
WO2020080871A2
(ko)
*
|
2018-10-18 |
2020-04-23 |
(주)신테카바이오 |
암 약물 반응성 판단을 위한 바이오 마커 조성물, 바이오 마커 조성물을 이용한 암 약물 반응성 판단 방법 및 암 약물 반응성 판단을 위한 바이오 마커 조성물 검출용 진단칩
|
|
SG11202108311RA
(en)
|
2019-02-26 |
2021-09-29 |
Janssen Biotech Inc |
Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
|
|
US10633693B1
(en)
|
2019-04-16 |
2020-04-28 |
Celsee Diagnostics, Inc. |
System and method for leakage control in a particle capture system
|
|
EP3966307B1
(en)
|
2019-05-07 |
2024-11-20 |
Bio-Rad Laboratories, Inc. |
System and method for automated single cell processing
|
|
US11273439B2
(en)
|
2019-05-07 |
2022-03-15 |
Bio-Rad Laboratories, Inc. |
System and method for target material retrieval from microwells
|
|
WO2020230091A1
(en)
|
2019-05-14 |
2020-11-19 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
|
US11850248B2
(en)
|
2019-05-14 |
2023-12-26 |
Yuhan Corporation |
Therapies with 3rd generation EGFR tyrosine kinase inhibitors
|
|
SG11202112898WA
(en)
|
2019-06-14 |
2021-12-30 |
Bio Rad Laboratories |
System and method for automated single cell processing and analyses
|
|
WO2021092476A1
(en)
|
2019-11-06 |
2021-05-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and systems for analyzing nucleic acid molecules
|
|
PH12022552076A1
(en)
|
2020-02-12 |
2023-11-29 |
Janssen Biotech Inc |
TREATMENT OF PATIENTS HAVING c-MET EXON 14 SKIPPING MUTATIONS
|
|
US11211147B2
(en)
|
2020-02-18 |
2021-12-28 |
Tempus Labs, Inc. |
Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
|
|
US11475981B2
(en)
|
2020-02-18 |
2022-10-18 |
Tempus Labs, Inc. |
Methods and systems for dynamic variant thresholding in a liquid biopsy assay
|
|
US11211144B2
(en)
|
2020-02-18 |
2021-12-28 |
Tempus Labs, Inc. |
Methods and systems for refining copy number variation in a liquid biopsy assay
|
|
CN111154881A
(zh)
*
|
2020-03-09 |
2020-05-15 |
南京实践医学检验有限公司 |
一种急性髓系白血病中基因突变的检测试剂盒及应用
|
|
US11504719B2
(en)
|
2020-03-12 |
2022-11-22 |
Bio-Rad Laboratories, Inc. |
System and method for receiving and delivering a fluid for sample processing
|
|
US20220025453A1
(en)
*
|
2020-07-23 |
2022-01-27 |
Michael Y Sha |
Xenonucleic acid-mediated multiplex qpcr clamping technology for lung cancer mutation detection
|
|
CN114107449B
(zh)
*
|
2020-08-31 |
2024-04-09 |
中山大学孙逸仙纪念医院 |
一种单细胞内原位qPCR方法
|
|
CN111996193B
(zh)
*
|
2020-09-11 |
2024-02-20 |
北京键凯科技股份有限公司 |
一种有效抑制表皮生长因子受体表达的siRNA序列
|
|
US11783912B2
(en)
|
2021-05-05 |
2023-10-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and systems for analyzing nucleic acid molecules
|
|
CN113564255A
(zh)
*
|
2021-08-13 |
2021-10-29 |
河北医科大学第四医院 |
一种lncRNA NEAT1_1的应用
|
|
DE102021126650A1
(de)
|
2021-10-14 |
2023-04-20 |
Rheinische Friedrich-Wilhelms-Universität Bonn, Körperschaft des öffentlichen Rechts |
Verfahren zur bestimmung der ansprechwahrscheinlichkeit einer malignen erkrankung auf eine behandlung mit einem pharmazeutischen hemmwirkstoff
|
|
WO2023107539A1
(en)
|
2021-12-10 |
2023-06-15 |
Bio-Rad Laboratories, Inc. |
Compositions, methods, and systems for sample processing with morphology-adjustable functionalized particles
|
|
CN114113265B
(zh)
*
|
2021-12-14 |
2023-08-08 |
郑州轻工业大学 |
一种适配体传感器及其制备方法
|
|
JPWO2023190967A1
(https=)
*
|
2022-03-31 |
2023-10-05 |
|
|
|
TW202515577A
(zh)
*
|
2023-06-27 |
2025-04-16 |
日商大鵬藥品工業股份有限公司 |
患有具有ｅｇｆｒ畸變的非小細胞肺癌之個體的治療方法
|
|
WO2025018697A1
(ko)
*
|
2023-07-14 |
2025-01-23 |
전남대학교산학협력단 |
암 진단을 위한 시료 처리 방법 및 이를 이용한 암 진단에 대한 정보 제공 방법
|
|
CN117778322B
(zh)
*
|
2023-12-17 |
2025-02-07 |
苏州拓维生物技术有限公司 |
一种对恩杂鲁胺耐药的细胞系的筛选方法及其应用
|