JP2009545620A5 - - Google Patents
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- Publication number
- JP2009545620A5 JP2009545620A5 JP2009523051A JP2009523051A JP2009545620A5 JP 2009545620 A5 JP2009545620 A5 JP 2009545620A5 JP 2009523051 A JP2009523051 A JP 2009523051A JP 2009523051 A JP2009523051 A JP 2009523051A JP 2009545620 A5 JP2009545620 A5 JP 2009545620A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- pharmaceutically acceptable
- acceptable salt
- use according
- vla
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83529006P | 2006-08-02 | 2006-08-02 | |
| PCT/US2007/075064 WO2008017025A2 (en) | 2006-08-02 | 2007-08-02 | Combination therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009545620A JP2009545620A (ja) | 2009-12-24 |
| JP2009545620A5 true JP2009545620A5 (https=) | 2010-09-09 |
Family
ID=38997866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009523051A Withdrawn JP2009545620A (ja) | 2006-08-02 | 2007-08-02 | 併用療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20100003224A1 (https=) |
| EP (1) | EP2068868A2 (https=) |
| JP (1) | JP2009545620A (https=) |
| CN (1) | CN101495115A (https=) |
| AR (1) | AR063470A1 (https=) |
| AU (1) | AU2007281090A1 (https=) |
| BR (1) | BRPI0714799A2 (https=) |
| CA (1) | CA2659463A1 (https=) |
| IL (1) | IL196556A0 (https=) |
| MX (1) | MX2009001272A (https=) |
| RU (1) | RU2009107030A (https=) |
| WO (1) | WO2008017025A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003261723A1 (en) | 2002-08-27 | 2004-03-19 | Takeda Chemical Industries, Ltd. | Cxcr4 antagonist and use thereof |
| WO2008075371A2 (en) | 2006-12-21 | 2008-06-26 | Biokine Therapeutics Ltd. | T-140 peptide analogs having cxcr4 super-agonist activity for immunomodulation |
| BRPI1009663A2 (pt) | 2009-06-14 | 2016-10-11 | Biokine Therapeutics Ltd | "método para elevação dos níveis plaquetários em um indivíduo com essa necessidade, método de inibição de hemorragia em um indivíduo que a necessite e composição farmacêutica" |
| JP2013541520A (ja) * | 2010-09-17 | 2013-11-14 | アンチセンス・セラピューティックス・リミテッド | 幹細胞および／または前駆細胞を動員するための方法 |
| WO2012129073A2 (en) * | 2011-03-18 | 2012-09-27 | University Of Virginia Patent Foundation | Compositions and methods for tissue engineering and cell based therapies |
| KR20140045411A (ko) | 2011-05-16 | 2014-04-16 | 젠자임 코포레이션 | Ｃｘｃｒ４ 길항제의 용도 |
| EP2720690A4 (en) * | 2011-06-16 | 2014-12-31 | Childrens Medical Center | COMBINED CHEMICAL MODIFICATION OF SPHINGOSIN-1-PHOSPHATE (S1P) AND CXCR4 SIGNALING PATHWAYS FOR HEMATOPOIETIC STEM CELL (HSC) MOBILIZATION AND TRANSPLANT |
| EP2841084B1 (en) | 2012-04-24 | 2018-05-30 | Biokine Therapeutics Ltd. | Cxcr4 antagonist peptide for use in the treatment of large cell lung cancer |
| CA2970114A1 (en) * | 2014-12-12 | 2016-06-16 | Commonwealth Scientific And Industrial Research Organisation | Dislodgement and release of hsc using alpha 9 integrin antagonist and cxcr4 antagonist |
| US10786547B2 (en) | 2015-07-16 | 2020-09-29 | Biokine Therapeutics Ltd. | Compositions, articles of manufacture and methods for treating cancer |
| KR102033920B1 (ko) | 2016-02-23 | 2019-10-18 | 바이오라인알엑스 리미티드 | 급성 골수성 백혈병을 치료하는 방법 |
| WO2017177167A1 (en) * | 2016-04-08 | 2017-10-12 | Syros Pharmaceuticals, Inc. | Rara agonists for the treatment of aml and mds |
| WO2018085574A2 (en) * | 2016-11-02 | 2018-05-11 | Washington University | Compositions comprising an integrin inhibitor and agents which interact with a chemokine and methods of use thereof |
| TWI734027B (zh) * | 2017-09-18 | 2021-07-21 | 泰宗生物科技股份有限公司 | 用於治療癌症之組合物 |
| CN111712262A (zh) * | 2017-12-06 | 2020-09-25 | 美真达治疗公司 | 用于动员造血干细胞和祖细胞的给药方案 |
| US11260079B2 (en) | 2017-12-06 | 2022-03-01 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001826A (en) * | 1989-12-21 | 1999-12-14 | Anormed, Inc. | Chemical compounds |
| US5021409A (en) * | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| GB9126677D0 (en) * | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| US6447766B1 (en) * | 1993-06-08 | 2002-09-10 | Smithkline Beecham Corporation | Method of mobilizing hematopoietic stem cells |
| ES2210255T3 (es) * | 1993-06-08 | 2004-07-01 | Smithkline Beecham Corporation | Metodos para mejorar la actividad biologica de quimiocinas. |
| US5510332A (en) * | 1994-07-07 | 1996-04-23 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor |
| CN1081685C (zh) * | 1994-08-19 | 2002-03-27 | 阿克佐诺贝尔公司 | 纤维素溶液及其制得的产品 |
| US6506770B1 (en) * | 1996-06-06 | 2003-01-14 | Anormed, Inc. | Antiviral compounds |
| US5968546A (en) * | 1997-05-16 | 1999-10-19 | Baur; Marcus | Keratinocyte culture from precursor cells |
| NZ509199A (en) * | 1998-05-28 | 2003-10-31 | Biogen Inc | A VLA-4 inhibitor: oMePUPA-V |
| US6365583B1 (en) * | 1999-02-02 | 2002-04-02 | Anormed, Inc. | Methods to enhance white blood cell count |
| US6750348B1 (en) * | 1999-03-24 | 2004-06-15 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| CZ2002518A3 (cs) * | 1999-08-13 | 2002-05-15 | Biogen, Inc. | Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují |
| AU2334301A (en) * | 1999-12-17 | 2001-06-25 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| US6734191B2 (en) * | 2000-09-15 | 2004-05-11 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| HK1052011A1 (zh) * | 2000-09-15 | 2003-08-29 | Anormed Inc. | 趋化因子受体结合杂环化合物 |
| DE60137435D1 (de) * | 2000-09-15 | 2009-03-05 | Anormed Inc | Chemokin rezeptor bindenden heterozyklische verbindungen |
| DE60136476D1 (de) * | 2000-09-29 | 2008-12-18 | Anormed Inc | -stickstoffhaltigen zyklischen polyaminen und deren verbindungen |
| WO2004091518A2 (en) * | 2003-04-11 | 2004-10-28 | Anormed Inc. | Cxcr4 chemokine receptor binding compounds |
| US7501518B2 (en) * | 2003-04-22 | 2009-03-10 | Genzyme Corporation | Methods of making 2,6-diaryl piperidine derivatives |
| JP4778420B2 (ja) * | 2003-04-22 | 2011-09-21 | アノーメッド インコーポレイティド | 増強された有効性を有するケモカインレセプタ結合複素環式化合物 |
| EP1708703A4 (en) * | 2003-12-11 | 2008-04-09 | Anormed Inc | CHEMOKIN RECEPTOR BINDING COMPOUNDS |
| EP1730113B1 (en) * | 2004-03-15 | 2016-12-28 | Genzyme Corporation | Process for the synthesis of a cxcr4 antagonist |
| JP2008509928A (ja) * | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆／幹細胞を動員するためのケモカインの組み合わせ |
| US7825088B2 (en) * | 2005-04-25 | 2010-11-02 | The Cbr Institute For Biomedical Research, Inc. | Methods for the treatment of multiple myeloma |
-
2007
- 2007-08-02 US US12/375,987 patent/US20100003224A1/en not_active Abandoned
- 2007-08-02 AR ARP070103423A patent/AR063470A1/es not_active Application Discontinuation
- 2007-08-02 CA CA002659463A patent/CA2659463A1/en not_active Abandoned
- 2007-08-02 BR BRPI0714799-6A patent/BRPI0714799A2/pt not_active Application Discontinuation
- 2007-08-02 MX MX2009001272A patent/MX2009001272A/es unknown
- 2007-08-02 RU RU2009107030/15A patent/RU2009107030A/ru not_active Application Discontinuation
- 2007-08-02 WO PCT/US2007/075064 patent/WO2008017025A2/en not_active Ceased
- 2007-08-02 CN CNA200780028588XA patent/CN101495115A/zh active Pending
- 2007-08-02 AU AU2007281090A patent/AU2007281090A1/en not_active Abandoned
- 2007-08-02 JP JP2009523051A patent/JP2009545620A/ja not_active Withdrawn
- 2007-08-02 EP EP07813695A patent/EP2068868A2/en not_active Withdrawn
-
2009
- 2009-01-15 IL IL196556A patent/IL196556A0/en unknown
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