JP2009542639A - グリコーゲン・シンターゼ・キナーゼ（ｇｓｋ３）に関連する疾患の治療のためのイミダゾール−ピリミジン誘導体 - Google Patents

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Publication number

JP2009542639A

JP2009542639A JP2009518045A JP2009518045A JP2009542639A JP 2009542639 A JP2009542639 A JP 2009542639A JP 2009518045 A JP2009518045 A JP 2009518045A JP 2009518045 A JP2009518045 A JP 2009518045A JP 2009542639 A JP2009542639 A JP 2009542639A

Authority

JP

Japan

Prior art keywords

alkyl

methyl

heterocycle

pyran

tetrahydro

Prior art date

2006-06-27

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

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• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 63
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• 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims description 12
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• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 10
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• 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 claims description 5
• WYLNTNIPADSGEA-UHFFFAOYSA-N 5-fluoro-4-[2-methyl-3-(oxan-4-yl)imidazol-4-yl]-n-[6-(morpholin-4-ylmethyl)pyridin-3-yl]pyrimidin-2-amine Chemical compound C1COCCC1N1C(C)=NC=C1C(C(=CN=1)F)=NC=1NC(C=N1)=CC=C1CN1CCOCC1 WYLNTNIPADSGEA-UHFFFAOYSA-N 0.000 claims description 4
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