JP2009542609A5 - - Google Patents
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- Publication number
- JP2009542609A5 JP2009542609A5 JP2009517409A JP2009517409A JP2009542609A5 JP 2009542609 A5 JP2009542609 A5 JP 2009542609A5 JP 2009517409 A JP2009517409 A JP 2009517409A JP 2009517409 A JP2009517409 A JP 2009517409A JP 2009542609 A5 JP2009542609 A5 JP 2009542609A5
- Authority
- JP
- Japan
- Prior art keywords
- wnt5a
- derivative
- therapeutically effective
- fragment
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 28
- 101000804792 Homo sapiens Protein Wnt-5a Proteins 0.000 claims 18
- 102000043366 Wnt-5a Human genes 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 14
- 229940079593 drug Drugs 0.000 claims 13
- 208000027418 Wounds and injury Diseases 0.000 claims 7
- 206010016654 Fibrosis Diseases 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 230000004761 fibrosis Effects 0.000 claims 5
- 230000003176 fibrotic effect Effects 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 4
- 230000009467 reduction Effects 0.000 claims 3
- 231100000241 scar Toxicity 0.000 claims 3
- 208000032544 Cicatrix Diseases 0.000 claims 2
- 208000002158 Proliferative Vitreoretinopathy Diseases 0.000 claims 2
- 206010038934 Retinopathy proliferative Diseases 0.000 claims 2
- 210000001015 abdomen Anatomy 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 210000003169 central nervous system Anatomy 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 208000021971 neovascular inflammatory vitreoretinopathy Diseases 0.000 claims 2
- 210000004197 pelvis Anatomy 0.000 claims 2
- 230000006785 proliferative vitreoretinopathy Effects 0.000 claims 2
- 230000037387 scars Effects 0.000 claims 2
- 230000001629 suppression Effects 0.000 claims 2
- 210000002435 tendon Anatomy 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 201000009273 Endometriosis Diseases 0.000 claims 1
- 206010018364 Glomerulonephritis Diseases 0.000 claims 1
- 206010023421 Kidney fibrosis Diseases 0.000 claims 1
- 108010043958 Peptoids Proteins 0.000 claims 1
- 208000032056 Radiation Fibrosis Syndrome Diseases 0.000 claims 1
- 206010067953 Radiation fibrosis Diseases 0.000 claims 1
- 206010039710 Scleroderma Diseases 0.000 claims 1
- 206010067269 Uterine fibrosis Diseases 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 230000001079 digestive effect Effects 0.000 claims 1
- 210000001508 eye Anatomy 0.000 claims 1
- 206010061989 glomerulosclerosis Diseases 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 208000023589 ischemic disease Diseases 0.000 claims 1
- 210000003041 ligament Anatomy 0.000 claims 1
- 210000000088 lip Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 230000004770 neurodegeneration Effects 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
- 210000003254 palate Anatomy 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 210000001428 peripheral nervous system Anatomy 0.000 claims 1
- 230000000750 progressive effect Effects 0.000 claims 1
- 208000005069 pulmonary fibrosis Diseases 0.000 claims 1
- 208000037803 restenosis Diseases 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0613031.4A GB0613031D0 (en) | 2006-06-30 | 2006-06-30 | Medicaments |
| PCT/GB2007/002445 WO2008001113A2 (en) | 2006-06-30 | 2007-06-29 | Use of wnt5a for inhibiting scarring |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009542609A JP2009542609A (ja) | 2009-12-03 |
| JP2009542609A5 true JP2009542609A5 (OSRAM) | 2010-08-19 |
Family
ID=36888398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009517409A Pending JP2009542609A (ja) | 2006-06-30 | 2007-06-29 | 薬剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20100137201A1 (OSRAM) |
| EP (1) | EP2046364A2 (OSRAM) |
| JP (1) | JP2009542609A (OSRAM) |
| CN (1) | CN101511383A (OSRAM) |
| AU (1) | AU2007263593A1 (OSRAM) |
| BR (1) | BRPI0713807A2 (OSRAM) |
| CA (1) | CA2656965A1 (OSRAM) |
| GB (1) | GB0613031D0 (OSRAM) |
| MX (1) | MX2008016520A (OSRAM) |
| WO (1) | WO2008001113A2 (OSRAM) |
| ZA (1) | ZA200900708B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0702930D0 (en) * | 2007-02-15 | 2007-03-28 | Renovo Ltd | Medicaments and methods for inhibition of scarring |
| WO2009047330A1 (en) * | 2007-10-12 | 2009-04-16 | Universite Louis Pasteur | Use of wnt5a for treating or preventing obesity and atherosclerosis |
| CN101790221B (zh) * | 2009-01-22 | 2015-05-06 | 中兴通讯股份有限公司 | 家用基站切换时网络接入控制方法及系统 |
| EP2226080A1 (en) * | 2009-03-05 | 2010-09-08 | Universiteit Maastricht | Antagonistic peptides for frizzled-1 and frizzled-2 |
| EP3668487A4 (en) * | 2017-08-20 | 2020-08-26 | The Regents of the University of California | MODULATION OF WNT5A TO TREAT GLAUCOMA |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6485972B1 (en) * | 1998-10-15 | 2002-11-26 | President And Fellows Of Harvard College | WNT signalling in reproductive organs |
| US20040087016A1 (en) * | 2000-05-12 | 2004-05-06 | University Of Utah Research Foundation | Compositions and methods for cell dedifferentiation and tissue regeneration |
| JP2004511209A (ja) * | 2000-05-12 | 2004-04-15 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション | 細胞の脱分化及び組織の再生のための組成物及び方法 |
| JP2004533829A (ja) * | 2001-04-06 | 2004-11-11 | インサイト・ゲノミックス・インコーポレイテッド | 細胞成長、分化および細胞死関連タンパク質 |
| WO2004047757A2 (en) * | 2002-11-21 | 2004-06-10 | University Of Massachusets | Diagnosing and treating hematopoietic cancers |
| US7374760B2 (en) * | 2003-05-15 | 2008-05-20 | The University Of Chicago | Methods and compositions for nerve regeneration |
| US20050261189A1 (en) * | 2004-04-16 | 2005-11-24 | Hydra Biosciences, Inc. | Methods of promoting cardiac cell proliferation |
| AU2005279771A1 (en) * | 2004-08-30 | 2006-03-09 | Theregen, Inc | Cultured three dimensional tissues and uses thereof |
-
2006
- 2006-06-30 GB GBGB0613031.4A patent/GB0613031D0/en not_active Ceased
-
2007
- 2007-06-29 BR BRPI0713807-5A patent/BRPI0713807A2/pt not_active IP Right Cessation
- 2007-06-29 US US12/306,501 patent/US20100137201A1/en not_active Abandoned
- 2007-06-29 AU AU2007263593A patent/AU2007263593A1/en not_active Abandoned
- 2007-06-29 ZA ZA200900708A patent/ZA200900708B/xx unknown
- 2007-06-29 WO PCT/GB2007/002445 patent/WO2008001113A2/en not_active Ceased
- 2007-06-29 JP JP2009517409A patent/JP2009542609A/ja active Pending
- 2007-06-29 MX MX2008016520A patent/MX2008016520A/es not_active Application Discontinuation
- 2007-06-29 CN CNA2007800318493A patent/CN101511383A/zh active Pending
- 2007-06-29 CA CA002656965A patent/CA2656965A1/en not_active Abandoned
- 2007-06-29 EP EP07766148A patent/EP2046364A2/en not_active Withdrawn
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