JP2009542219A5 - - Google Patents

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Publication number
JP2009542219A5
JP2009542219A5 JP2009518433A JP2009518433A JP2009542219A5 JP 2009542219 A5 JP2009542219 A5 JP 2009542219A5 JP 2009518433 A JP2009518433 A JP 2009518433A JP 2009518433 A JP2009518433 A JP 2009518433A JP 2009542219 A5 JP2009542219 A5 JP 2009542219A5
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JP
Japan
Prior art keywords
asparaginase
recombinant
enzyme
seq
host cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2009518433A
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English (en)
Japanese (ja)
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JP2009542219A (ja
JP5308333B2 (ja
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Publication date
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Priority claimed from PCT/US2007/070706 external-priority patent/WO2008011234A2/en
Publication of JP2009542219A publication Critical patent/JP2009542219A/ja
Publication of JP2009542219A5 publication Critical patent/JP2009542219A5/ja
Application granted granted Critical
Publication of JP5308333B2 publication Critical patent/JP5308333B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009518433A 2006-06-30 2007-06-08 L−アスパラギナーゼiiを産生する組換え宿主 Active JP5308333B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81781706P 2006-06-30 2006-06-30
US60/817,817 2006-06-30
PCT/US2007/070706 WO2008011234A2 (en) 2006-06-30 2007-06-08 Recombinant host for producing l-asparaginase ii

Publications (3)

Publication Number Publication Date
JP2009542219A JP2009542219A (ja) 2009-12-03
JP2009542219A5 true JP2009542219A5 (https=) 2010-07-29
JP5308333B2 JP5308333B2 (ja) 2013-10-09

Family

ID=38957454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009518433A Active JP5308333B2 (ja) 2006-06-30 2007-06-08 L−アスパラギナーゼiiを産生する組換え宿主

Country Status (17)

Country Link
US (2) US7807436B2 (https=)
EP (1) EP2046369B1 (https=)
JP (1) JP5308333B2 (https=)
KR (1) KR101408062B1 (https=)
CN (1) CN101484181B (https=)
AU (1) AU2007275535B2 (https=)
CA (1) CA2652718A1 (https=)
DK (1) DK2046369T3 (https=)
ES (1) ES2553329T3 (https=)
HU (1) HUE025738T2 (https=)
IL (1) IL195168A (https=)
MX (1) MX2009000284A (https=)
NZ (1) NZ572519A (https=)
PL (1) PL2046369T3 (https=)
PT (1) PT2046369E (https=)
TW (1) TWI427148B (https=)
WO (1) WO2008011234A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102014000585B1 (pt) 2014-01-10 2021-01-12 Coppe/Ufrj-Instituto Alberto Luiz Coimbra De Pós-Graduação l-asparaginase recombinante de zymomonas
CN105802948B (zh) 2014-12-29 2020-06-09 江苏众红生物工程创药研究院有限公司 聚乙二醇定点修饰的门冬酰胺酶及其制备方法与应用
WO2016204503A1 (ko) * 2015-06-15 2016-12-22 아주대학교 산학협력단 재조합 미생물을 이용한 천연고무의 생산 방법
CN109640961B (zh) 2016-06-01 2021-11-02 施维雅知识产权英国有限公司 聚亚烷基氧化物-天冬酰胺酶制剂及其制备和使用方法
KR101837636B1 (ko) * 2016-06-14 2018-03-12 전남대학교산학협력단 코리네박테리움 재조합 균주를 이용한 아스파라기나제의 분비생산 방법
CN108795832B (zh) * 2017-04-26 2021-05-14 江苏恒瑞医药股份有限公司 一种内源l-门冬酰胺酶ii基因敲除的宿主菌、其制备方法及其应用
EP3701036A4 (en) * 2017-10-27 2021-09-01 Pfenex Inc. PROCESS FOR PRODUCING ASPARAGINASE OF E. COLI
JP7784804B2 (ja) 2017-10-27 2025-12-12 フェネックス インク. 組み換えerwiniaアスパラギナーゼの製造のための方法
CN113453677A (zh) 2018-12-13 2021-09-28 沪亚生物国际有限责任公司 用于治疗急性心房颤动的舒卡定施用
AU2021410080A1 (en) 2020-12-23 2023-06-22 Jazz Pharmaceuticals Ireland Ltd. Methods of purifying charge-shielded fusion proteins
CN114854729B (zh) * 2021-02-03 2025-09-02 重庆派金生物科技有限公司 定向化学偶联门冬酰胺酶突变体及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324844A (en) 1989-04-19 1994-06-28 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5122614A (en) 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5919455A (en) 1993-10-27 1999-07-06 Enzon, Inc. Non-antigenic branched polymer conjugates
US5615460A (en) * 1994-06-06 1997-04-01 The Procter & Gamble Company Female component for refastenable fastening device having regions of differential extensibility
US6180095B1 (en) 1997-12-17 2001-01-30 Enzon, Inc. Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
US5965119A (en) 1997-12-30 1999-10-12 Enzon, Inc. Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
US6958212B1 (en) 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US7122189B2 (en) 2002-08-13 2006-10-17 Enzon, Inc. Releasable polymeric conjugates based on aliphatic biodegradable linkers
US7087229B2 (en) 2003-05-30 2006-08-08 Enzon Pharmaceuticals, Inc. Releasable polymeric conjugates based on aliphatic biodegradable linkers
CN100502944C (zh) * 2005-09-16 2009-06-24 北京双鹭药业股份有限公司 一种天门冬酰胺酶注射液、其制备方法及应用

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