JP2009541240A - スタウロスポリンを含む組み合わせ - Google Patents
スタウロスポリンを含む組み合わせ Download PDFInfo
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- JP2009541240A JP2009541240A JP2009515774A JP2009515774A JP2009541240A JP 2009541240 A JP2009541240 A JP 2009541240A JP 2009515774 A JP2009515774 A JP 2009515774A JP 2009515774 A JP2009515774 A JP 2009515774A JP 2009541240 A JP2009541240 A JP 2009541240A
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- mcl
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- lower alkyl
- amino
- hydrogen
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- GBXQPDCOMJJCMJ-UHFFFAOYSA-M trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C GBXQPDCOMJJCMJ-UHFFFAOYSA-M 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0612542.1A GB0612542D0 (en) | 2006-06-23 | 2006-06-23 | Combinations comprising staurosporines |
| PCT/EP2007/005517 WO2007147613A2 (en) | 2006-06-23 | 2007-06-22 | Combinations comprising staurosprorines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009541240A true JP2009541240A (ja) | 2009-11-26 |
| JP2009541240A5 JP2009541240A5 (enExample) | 2010-08-05 |
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| JP2009515774A Pending JP2009541240A (ja) | 2006-06-23 | 2007-06-22 | スタウロスポリンを含む組み合わせ |
Country Status (12)
| Country | Link |
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| US (1) | US20100184820A1 (enExample) |
| EP (1) | EP2037933A2 (enExample) |
| JP (1) | JP2009541240A (enExample) |
| KR (1) | KR20090033874A (enExample) |
| CN (1) | CN101505760A (enExample) |
| AU (1) | AU2007263278A1 (enExample) |
| BR (1) | BRPI0713730A2 (enExample) |
| CA (1) | CA2655724A1 (enExample) |
| GB (1) | GB0612542D0 (enExample) |
| MX (1) | MX2008016488A (enExample) |
| RU (1) | RU2009101972A (enExample) |
| WO (1) | WO2007147613A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014523426A (ja) * | 2011-06-22 | 2014-09-11 | トゥルン イリオピスト | 併用療法 |
| JP2015527316A (ja) * | 2012-07-13 | 2015-09-17 | トゥルン イリオピスト | 併用療法ｉｉｉ |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009143578A1 (en) * | 2008-05-28 | 2009-12-03 | The Council Of The Queensland Institute Of Medical Research | Cancer drug target and methods of diagnosis and therapy |
| CN102101866A (zh) * | 2010-11-04 | 2011-06-22 | 中国海洋大学 | 十字孢碱卤代衍生物及其制备方法和应用 |
| FI20115876A0 (fi) | 2011-09-06 | 2011-09-06 | Turun Yliopisto | Yhdistelmähoito |
| CN110526903B (zh) * | 2016-06-01 | 2021-12-10 | 中国海洋大学 | 双吲哚马来酰亚胺衍生物及其制备方法和用途 |
| CN106083830B (zh) * | 2016-06-01 | 2019-07-12 | 中国海洋大学 | 双吲哚马来酰亚胺衍生物及其制备方法和用途 |
| SG10201607303YA (en) | 2016-09-01 | 2018-04-27 | Agency Science Tech & Res | Antisense oligonucleotides to induce exon skipping |
| WO2019000224A1 (zh) * | 2017-06-27 | 2019-01-03 | 中国海洋大学 | 双吲哚马来酰亚胺衍生物及其制备方法和用途 |
| CN107569491A (zh) * | 2017-08-30 | 2018-01-12 | 杭州科兴生物化工有限公司 | 一种星孢菌素类化合物的应用 |
| AU2022291381B2 (en) | 2021-06-11 | 2025-04-24 | Gilead Sciences, Inc. | Combination mcl-1 inhibitors with anti-cancer agents |
| EP4351657A1 (en) | 2021-06-11 | 2024-04-17 | Gilead Sciences, Inc. | Combination mcl-1 inhibitors with anti-body drug conjugates |
| CN114437109B (zh) * | 2022-03-08 | 2023-09-29 | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 一种十字孢碱卤代衍生物及其制备方法与应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002534073A (ja) * | 1999-01-07 | 2002-10-15 | アイシス・ファーマシューティカルス・インコーポレーテッド | 新規抗アポトーシスｂｃｌ−２−関連タンパク質のアンチセンスモジュレーション |
| WO2005014004A1 (en) * | 2003-08-08 | 2005-02-17 | Novartis Ag | Combinations comprising staurosporines |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1441737B1 (en) * | 2001-10-30 | 2006-08-09 | Novartis AG | Staurosporine derivatives as inhibitors of flt3 receptor tyrosine kinase activity |
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2006
- 2006-06-23 GB GBGB0612542.1A patent/GB0612542D0/en not_active Ceased
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2007
- 2007-06-22 RU RU2009101972/15A patent/RU2009101972A/ru unknown
- 2007-06-22 AU AU2007263278A patent/AU2007263278A1/en not_active Abandoned
- 2007-06-22 US US12/305,390 patent/US20100184820A1/en not_active Abandoned
- 2007-06-22 WO PCT/EP2007/005517 patent/WO2007147613A2/en not_active Ceased
- 2007-06-22 JP JP2009515774A patent/JP2009541240A/ja active Pending
- 2007-06-22 CA CA002655724A patent/CA2655724A1/en not_active Abandoned
- 2007-06-22 BR BRPI0713730-3A patent/BRPI0713730A2/pt not_active IP Right Cessation
- 2007-06-22 CN CNA200780030602XA patent/CN101505760A/zh active Pending
- 2007-06-22 KR KR1020097001396A patent/KR20090033874A/ko not_active Withdrawn
- 2007-06-22 MX MX2008016488A patent/MX2008016488A/es not_active Application Discontinuation
- 2007-06-22 EP EP07764787A patent/EP2037933A2/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002534073A (ja) * | 1999-01-07 | 2002-10-15 | アイシス・ファーマシューティカルス・インコーポレーテッド | 新規抗アポトーシスｂｃｌ−２−関連タンパク質のアンチセンスモジュレーション |
| WO2005014004A1 (en) * | 2003-08-08 | 2005-02-17 | Novartis Ag | Combinations comprising staurosporines |
Non-Patent Citations (4)
| Title |
|---|
| JPN5009008559; ＡＩＣＨＢＥＲＧＥＲ ＫＡＲＬ Ｊ: ＢＬＯＯＤ Ｖ１０６ Ｎ１１ ＰＡＲＴ１, 20051116, Ｐ９８２Ａ * |
| JPN5009008560; ＡＩＣＨＢＥＲＧＥＲ ＫＡＲＬ Ｊ: ＢＬＯＯＤ Ｖ１０５ Ｎ８, 20050415, Ｐ３３０３-３３１１ * |
| JPN5009008561; ＣＨＡＬＡＮＤＯＮ ＹＶＥＳ: ＨＡＥＭＡＴＯＬＯＧＩＣＡ／ＴＨＥ ＨＥＭＡＴＯＬＯＧＹ ＪＯＵＲＮＡＬ Ｖ９０ Ｎ７, 200507, Ｐ９４９-９６８ * |
| JPN5009008562; ＧＬＥＩＸＮＥＲ ＫＡＲＯＬＩＮＥ Ｖ: ＢＬＯＯＤ Ｖ１０７ Ｎ２, 20060115, Ｐ７５２-７５９ * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014523426A (ja) * | 2011-06-22 | 2014-09-11 | トゥルン イリオピスト | 併用療法 |
| JP2015527316A (ja) * | 2012-07-13 | 2015-09-17 | トゥルン イリオピスト | 併用療法ｉｉｉ |
| US10166241B2 (en) | 2012-07-13 | 2019-01-01 | Turun Yliopisto | Combination Therapy III |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090033874A (ko) | 2009-04-06 |
| CN101505760A (zh) | 2009-08-12 |
| WO2007147613A2 (en) | 2007-12-27 |
| WO2007147613A3 (en) | 2008-07-03 |
| AU2007263278A1 (en) | 2007-12-27 |
| BRPI0713730A2 (pt) | 2012-10-30 |
| CA2655724A1 (en) | 2007-12-27 |
| MX2008016488A (es) | 2009-01-22 |
| GB0612542D0 (en) | 2006-08-02 |
| RU2009101972A (ru) | 2010-07-27 |
| EP2037933A2 (en) | 2009-03-25 |
| US20100184820A1 (en) | 2010-07-22 |
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