KR20090033874A

KR20090033874A - 스타우로스포린을 포함하는 조합물

스타우로스포린을 포함하는 조합물 Download PDF

Info

Publication number: KR20090033874A
Authority: KR; South Korea
Prior art keywords: mcl; substituted; typically; lower alkyl; amino
Prior art date: 2006-06-23
Legal status : Withdrawn

Application number

KR1020097001396A

Other languages

English (en)

Korean (ko)

Inventor

피터 발렌트

Original Assignee

노파르티스 아게

Priority date

2006-06-23

Filing date

2007-06-22

Publication date

2009-04-06

2007-06-22 Application filed by 노파르티스 아게 filed Critical 노파르티스 아게

2009-04-06 Publication of KR20090033874A publication Critical patent/KR20090033874A/ko

Status Withdrawn legal-status Critical Current

Links

HKSZLNNOFSGOKW-FYTWVXJKSA-N staurosporine Chemical compound C12=C3N4C5=CC=CC=C5C3=C3CNC(=O)C3=C2C2=CC=CC=C2N1[C@H]1C[C@@H](NC)[C@@H](OC)[C@]4(C)O1 HKSZLNNOFSGOKW-FYTWVXJKSA-N 0.000 title claims description 12
HKSZLNNOFSGOKW-UHFFFAOYSA-N ent-staurosporine Natural products C12=C3N4C5=CC=CC=C5C3=C3CNC(=O)C3=C2C2=CC=CC=C2N1C1CC(NC)C(OC)C4(C)O1 HKSZLNNOFSGOKW-UHFFFAOYSA-N 0.000 title description 4
101001056180 Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1 Proteins 0.000 claims abstract description 240
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FSPQCTGGIANIJZ-UHFFFAOYSA-N 2-[[(3,4-dimethoxyphenyl)-oxomethyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide Chemical compound C1=C(OC)C(OC)=CC=C1C(=O)NC1=C(C(N)=O)C(CCCC2)=C2S1 FSPQCTGGIANIJZ-UHFFFAOYSA-N 0.000 claims abstract description 42
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