JP2009539387A5 - - Google Patents
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- Publication number
- JP2009539387A5 JP2009539387A5 JP2009514641A JP2009514641A JP2009539387A5 JP 2009539387 A5 JP2009539387 A5 JP 2009539387A5 JP 2009514641 A JP2009514641 A JP 2009514641A JP 2009514641 A JP2009514641 A JP 2009514641A JP 2009539387 A5 JP2009539387 A5 JP 2009539387A5
- Authority
- JP
- Japan
- Prior art keywords
- embryo
- interphase
- period
- cell
- determining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 31
- 230000016507 interphase Effects 0.000 claims description 27
- 210000001161 mammalian embryo Anatomy 0.000 claims description 26
- 230000032823 cell division Effects 0.000 claims description 21
- 230000009087 cell motility Effects 0.000 claims description 15
- 210000004027 cell Anatomy 0.000 claims description 7
- 230000033001 locomotion Effects 0.000 claims description 7
- 210000003463 organelle Anatomy 0.000 claims description 7
- 238000012544 monitoring process Methods 0.000 claims description 6
- 238000002513 implantation Methods 0.000 claims 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81411506P | 2006-06-16 | 2006-06-16 | |
| DKPA200600821 | 2006-06-16 | ||
| DKPA200600821 | 2006-06-16 | ||
| US60/814,115 | 2006-06-16 | ||
| PCT/DK2006/000581 WO2007042044A1 (en) | 2005-10-14 | 2006-10-16 | Determination of a change in a cell population |
| DKPCT/DK2006/000581 | 2006-10-16 | ||
| DKPA200700571 | 2007-04-19 | ||
| DKPA200700571 | 2007-04-19 | ||
| PCT/DK2007/000291 WO2007144001A2 (en) | 2006-06-16 | 2007-06-15 | Embryo quality assessment based on blastomere division and movement |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013141334A Division JP5732110B2 (ja) | 2006-06-16 | 2013-07-05 | 卵割球の分裂および運動に基づく胚品質の評価 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009539387A JP2009539387A (ja) | 2009-11-19 |
| JP2009539387A5 true JP2009539387A5 (https=) | 2010-03-11 |
| JP5731748B2 JP5731748B2 (ja) | 2015-06-10 |
Family
ID=43414894
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009514641A Active JP5731748B2 (ja) | 2006-06-16 | 2007-06-15 | 卵割球の分裂および運動に基づく胚品質の評価 |
| JP2013141334A Active JP5732110B2 (ja) | 2006-06-16 | 2013-07-05 | 卵割球の分裂および運動に基づく胚品質の評価 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013141334A Active JP5732110B2 (ja) | 2006-06-16 | 2013-07-05 | 卵割球の分裂および運動に基づく胚品質の評価 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20100041090A1 (https=) |
| EP (2) | EP2035548B1 (https=) |
| JP (2) | JP5731748B2 (https=) |
| CN (2) | CN101495619B (https=) |
| AT (1) | ATE477499T1 (https=) |
| DE (1) | DE602007008419D1 (https=) |
| DK (1) | DK2035548T3 (https=) |
| WO (1) | WO2007144001A2 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2549205T3 (es) | 2005-10-14 | 2015-10-26 | Unisense Fertilitech A/S | Determinación de un cambio en una población de células |
| DE602008005746D1 (de) | 2007-06-29 | 2011-05-05 | Unisense Fertilitech As | Vorrichtung, system und verfahren zur beobachtung und/oder kultivierung mikroskopischer objekte |
| GB0719037D0 (en) | 2007-09-28 | 2007-11-07 | Vitrolife Sweden Ab | Sampling needle |
| WO2010003423A2 (en) * | 2008-07-05 | 2010-01-14 | Unisense Fertilitech A/S | One to one identification system |
| CN104293646A (zh) | 2009-08-22 | 2015-01-21 | 里兰斯坦福初级大学理事会 | 成像并评估胚胎、卵母细胞和干细胞 |
| GB201006046D0 (en) * | 2010-04-12 | 2010-05-26 | Ge Healthcare Uk Ltd | System and method for determining motion of a biological object |
| JP5807288B2 (ja) * | 2010-06-30 | 2015-11-10 | 大日本印刷株式会社 | 体外培養による胚の製造方法、並びに胚を選別するための方法、装置、及びシステム |
| JP5962828B2 (ja) * | 2010-06-30 | 2016-08-03 | 大日本印刷株式会社 | 体外培養による胚の製造方法、並びに胚を選別するための方法、装置、及びシステム |
| CA2812776C (en) * | 2010-09-27 | 2022-05-17 | Auxogyn, Inc. | Apparatus, method, and system for the automated imaging and evaluation of embryos, oocytes, and stem cells |
| RU2441243C1 (ru) * | 2010-11-12 | 2012-01-27 | Федеральное государственное учреждение "Ивановский научно-исследовательский институт материнства и детства имени В.Н. Городкова" Министерства здравоохранения и социального развития Российской Федерации | Способ прогнозирования качества эмбриона при проведении эко у женщин с бесплодием |
| GR1007617B (el) * | 2011-01-24 | 2012-06-20 | Ιδρυμα Τεχνολογιας Και Ερευνας - Ιτε, | Χρηση μη-γραμμικων απεικονιστικων τεχνικων για την αξιολογηση της ποιοτητας εμβρυων προεμφυτευτικου σταδιου και την προωθηση επιτυχους εγκυμοσυνης |
| EP2678675B1 (en) | 2011-02-23 | 2017-10-11 | The Board of Trustees of the Leland Stanford Junior University | Methods of detecting aneuploidy in human embryos |
| CN104232566B (zh) * | 2011-05-31 | 2016-11-16 | 尤尼森斯繁殖技术公司 | 基于卵裂球的卵裂和形态的胚胎质量评估 |
| WO2013004239A1 (en) | 2011-07-02 | 2013-01-10 | Unisense Fertilitech A/S | Adaptive embryo selection criteria optimized through iterative customization and collaboration |
| EP2855664B1 (en) | 2012-05-31 | 2017-10-04 | Unisense Fertilitech A/S | Embryo quality assessment based on blastocyst development |
| WO2013181549A2 (en) * | 2012-05-31 | 2013-12-05 | Auxogyn, Inc. | In vitro embryo blastocyst prediction methods |
| IN2014DN10790A (https=) * | 2012-06-25 | 2015-09-04 | Unisense Fertilitech As | |
| CN104755608A (zh) * | 2012-08-30 | 2015-07-01 | 尤尼森斯繁殖技术公司 | 体外培养胚胎的自动化监控 |
| US10241108B2 (en) | 2013-02-01 | 2019-03-26 | Ares Trading S.A. | Abnormal syngamy phenotypes observed with time lapse imaging for early identification of embryos with lower development potential |
| CN105408746A (zh) | 2013-02-28 | 2016-03-16 | 普罗吉涅股份有限公司 | 基于图像的人胚胎细胞分类的装置、方法和系统 |
| JP2014193145A (ja) * | 2013-03-01 | 2014-10-09 | Naoki Yamashita | 胚盤胞培養液中のノルエピネフリン量によるヒト胚盤胞の評価方法 |
| WO2014202696A1 (en) * | 2013-06-18 | 2014-12-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for determining the quality of an embryo |
| US10942170B2 (en) | 2014-03-20 | 2021-03-09 | Ares Trading S.A. | Quantitative measurement of human blastocyst and morula morphology developmental kinetics |
| WO2015192352A1 (zh) * | 2014-06-19 | 2015-12-23 | 湖南光琇高新生命科技有限公司 | 一种根据分裂行为对体外受精治疗胚胎进行评估的等级分类方法 |
| US10510143B1 (en) * | 2015-09-21 | 2019-12-17 | Ares Trading S.A. | Systems and methods for generating a mask for automated assessment of embryo quality |
| US11494578B1 (en) | 2015-09-21 | 2022-11-08 | Ares Trading S.A. | Systems and methods for automated assessment of embryo quality using image based features |
| JP2018014991A (ja) * | 2016-07-13 | 2018-02-01 | ソニー株式会社 | 情報処理装置、情報処理方法及び情報処理システム |
| JP2018022216A (ja) * | 2016-08-01 | 2018-02-08 | ソニー株式会社 | 情報処理装置、情報処理方法、及びプログラム |
| JP7001060B2 (ja) | 2016-11-02 | 2022-01-19 | ソニーグループ株式会社 | 情報処理装置、情報処理方法及び情報処理システム |
| JP6977293B2 (ja) * | 2017-03-31 | 2021-12-08 | ソニーグループ株式会社 | 情報処理装置、情報処理方法、プログラム及び観察システム |
| JP7100431B2 (ja) * | 2017-07-14 | 2022-07-13 | 株式会社ニコン | 受精卵判定装置、受精卵判定システム、及び受精卵判定プログラム |
| DE112018004960T5 (de) | 2017-10-26 | 2020-07-23 | Sony Corporation | Informationsverarbeitungseinrichtung, informationsverarbeitungsverfahren, programm und beobachtungssystem |
| JP6732722B2 (ja) * | 2017-12-11 | 2020-08-05 | 憲隆 福永 | 胚選抜システム |
| EP3812449A4 (en) * | 2018-06-20 | 2022-03-23 | JCR Pharmaceuticals Co., Ltd. | Analysis software and device for embryo selection |
| GB201810634D0 (en) * | 2018-06-28 | 2018-08-15 | Vitrolife As | Methods and apparatus for assessing embryo development |
| CN109214437A (zh) * | 2018-08-22 | 2019-01-15 | 湖南自兴智慧医疗科技有限公司 | 一种基于机器学习的ivf-et早孕胚胎发育预测系统 |
| CN114467112B (zh) * | 2019-09-06 | 2025-04-15 | 布里格姆妇女医院 | 用于辅助生殖程序的质量保证度量的自动评估 |
| WO2022031765A1 (en) * | 2020-08-03 | 2022-02-10 | Emgenisys, Inc. | Embryo evaluation based on real-time video |
| JP2024054578A (ja) | 2022-10-05 | 2024-04-17 | 株式会社アステック | タイムラプス撮影機能付き培養装置および培養方法 |
| CN116091421B (zh) * | 2022-12-16 | 2026-04-10 | 中山大学 | 一种体外受精胚胎卵裂球图像自动分割及面积计算的方法 |
| CN116758539B (zh) * | 2023-08-17 | 2023-10-31 | 武汉互创联合科技有限公司 | 一种基于数据增强的胚胎图像卵裂球识别方法 |
Family Cites Families (28)
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| US3618734A (en) * | 1969-06-10 | 1971-11-09 | Res Foundation Of Children S H | Specimen incubator |
| DE2940446C2 (de) * | 1979-10-05 | 1982-07-08 | B. Braun Melsungen Ag, 3508 Melsungen | Züchtung von tierischen Zellen in Suspensions- und Monolayerkulturen in Fermentationsgefäßen |
| US4724543A (en) * | 1985-09-10 | 1988-02-09 | Beckman Research Institute, City Of Hope | Method and apparatus for automatic digital image analysis |
| JP2559760B2 (ja) * | 1987-08-31 | 1996-12-04 | 株式会社日立製作所 | 細胞搬送方法 |
| US5196168A (en) * | 1991-12-19 | 1993-03-23 | Eastman Kodak Company | Incubator with positioning device for slide elements |
| DE69319983T2 (de) * | 1992-09-28 | 1999-02-18 | Becton Dickinson And Co., Franklin Lakes, N.J. | Zellkultureinsatz |
| US5763279A (en) * | 1993-09-09 | 1998-06-09 | Synthecon, Inc. | Gas permeable bioreactor and method of use |
| US5968340A (en) * | 1997-04-07 | 1999-10-19 | Marine Biological Laboratory | Polarographic self-referencing probe and method for using |
| US6228636B1 (en) * | 1998-09-21 | 2001-05-08 | Matsushita Electric Industrial Co., Ltd. | Incubator |
| DE19903506C2 (de) * | 1999-01-29 | 2002-04-04 | Inst Chemo Biosensorik | Verfahren, Gefäß und Vorrichtung zur Überwachung der Stoffwechselaktivität von Zellkulturen in flüssigen Medien |
| US6391577B1 (en) * | 1999-03-03 | 2002-05-21 | Susan R. Mikkelsen | Rapid electrochemical assay for antibiotic and cytotoxic drug susceptibility in microorganisms |
| JP3442357B2 (ja) * | 2000-08-25 | 2003-09-02 | 株式会社日立製作所 | 両生類卵母細胞試料導入装置、両生類卵母細胞試料導入システム、両生類卵母細胞試料導入方法、両生類卵母細胞の製造方法、両生類卵母細胞及びそれを販売又は譲渡する方法、スクリーニング用のセンサーとして用いる方法、容器、及び解析方法 |
| US6434320B1 (en) * | 2000-10-13 | 2002-08-13 | Comtrak Technologies, Llc | Method of searching recorded digital video for areas of activity |
| US6555365B2 (en) * | 2000-12-07 | 2003-04-29 | Biocrystal, Ltd. | Microincubator comprising a cell culture apparatus and a transparent heater |
| US7015031B2 (en) * | 2002-01-24 | 2006-03-21 | Genx International, Inc. | Biological specimen-culturing system and method with onboard specimen development sensors |
| EP1486067B1 (en) * | 2002-02-13 | 2015-04-15 | Reify Corporation | Method and apparatus for acquisition, compression, and characterization of spatiotemporal signals |
| US7326565B2 (en) * | 2002-11-19 | 2008-02-05 | Sanyo Electric Co., Ltd. | Storage apparatus |
| WO2005028519A2 (en) * | 2003-02-19 | 2005-03-31 | Vanderbilt University | Polymer matrixes having nanoscale channels and uses |
| US7372985B2 (en) * | 2003-08-15 | 2008-05-13 | Massachusetts Institute Of Technology | Systems and methods for volumetric tissue scanning microscopy |
| US7239719B2 (en) * | 2003-08-22 | 2007-07-03 | Bbn Technologies Corp. | Automatic target detection and motion analysis from image data |
| EP1695080A1 (en) * | 2003-08-28 | 2006-08-30 | Coopersurgical, Inc. | Method for determining embryo quality |
| US20070015289A1 (en) * | 2003-09-19 | 2007-01-18 | Kao H P | Dispenser array spotting |
| JP3950972B2 (ja) * | 2003-11-14 | 2007-08-01 | 国立大学法人名古屋大学 | 生物試料の生物発光測定装置 |
| KR20060127003A (ko) * | 2003-12-19 | 2006-12-11 | 유니버시티 오브 워터루 | 배양된 세포 및 세포 배양 방법 및 장치 |
| US7336401B2 (en) * | 2003-12-19 | 2008-02-26 | Xerox Corporation | Systems and methods for estimating an image marking process using event mapping of scanned image attributes |
| JP4333426B2 (ja) * | 2004-03-19 | 2009-09-16 | ソニー株式会社 | 化合物半導体の製造方法、及び半導体装置の製造方法 |
| ES2549205T3 (es) * | 2005-10-14 | 2015-10-26 | Unisense Fertilitech A/S | Determinación de un cambio en una población de células |
| US20080056952A1 (en) * | 2006-08-25 | 2008-03-06 | Angros Lee H | Analytic plates with markable portions and methods of use |
-
2007
- 2007-06-15 EP EP07722668A patent/EP2035548B1/en not_active Revoked
- 2007-06-15 JP JP2009514641A patent/JP5731748B2/ja active Active
- 2007-06-15 US US12/304,905 patent/US20100041090A1/en not_active Abandoned
- 2007-06-15 AT AT07722668T patent/ATE477499T1/de not_active IP Right Cessation
- 2007-06-15 CN CN200780027901.8A patent/CN101495619B/zh not_active Expired - Fee Related
- 2007-06-15 CN CN201210428780.0A patent/CN103074410B/zh not_active Expired - Fee Related
- 2007-06-15 DK DK07722668.6T patent/DK2035548T3/da active
- 2007-06-15 DE DE602007008419T patent/DE602007008419D1/de active Active
- 2007-06-15 EP EP10172399A patent/EP2282210A1/en not_active Withdrawn
- 2007-06-15 WO PCT/DK2007/000291 patent/WO2007144001A2/en not_active Ceased
-
2012
- 2012-01-31 US US13/362,895 patent/US20120309043A1/en not_active Abandoned
- 2012-07-31 US US13/562,989 patent/US20130102837A1/en not_active Abandoned
- 2012-10-01 US US13/632,505 patent/US20130225917A1/en not_active Abandoned
-
2013
- 2013-07-05 JP JP2013141334A patent/JP5732110B2/ja active Active
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