JP2009538147A5 - - Google Patents
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- Publication number
- JP2009538147A5 JP2009538147A5 JP2009512311A JP2009512311A JP2009538147A5 JP 2009538147 A5 JP2009538147 A5 JP 2009538147A5 JP 2009512311 A JP2009512311 A JP 2009512311A JP 2009512311 A JP2009512311 A JP 2009512311A JP 2009538147 A5 JP2009538147 A5 JP 2009538147A5
- Authority
- JP
- Japan
- Prior art keywords
- plasmid dna
- endotoxin
- deletion strain
- multiple deletion
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000013612 plasmid Substances 0.000 claims description 44
- 239000002158 endotoxin Substances 0.000 claims description 35
- 238000012217 deletion Methods 0.000 claims description 26
- 230000037430 deletion Effects 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 15
- 241000894006 Bacteria Species 0.000 claims description 14
- 241000588724 Escherichia coli Species 0.000 claims description 14
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- 230000000968 intestinal effect Effects 0.000 claims description 5
- 229920006008 lipopolysaccharide Polymers 0.000 claims description 5
- 241000894007 species Species 0.000 claims description 5
- 101100021843 Shigella flexneri lpxM1 gene Proteins 0.000 claims description 4
- 101100021844 Shigella flexneri lpxM2 gene Proteins 0.000 claims description 4
- 239000000427 antigen Substances 0.000 claims description 4
- 108091007433 antigens Proteins 0.000 claims description 4
- 102000036639 antigens Human genes 0.000 claims description 4
- 101150060640 lpxM gene Proteins 0.000 claims description 4
- 239000006166 lysate Substances 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 2
- 230000002934 lysing effect Effects 0.000 claims description 2
- 230000001902 propagating effect Effects 0.000 claims description 2
- 238000000746 purification Methods 0.000 claims 2
- 101000980463 Treponema pallidum (strain Nichols) Chaperonin GroEL Proteins 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80850006P | 2006-05-24 | 2006-05-24 | |
| US60/808,500 | 2006-05-24 | ||
| PCT/US2007/069685 WO2007140274A1 (en) | 2006-05-24 | 2007-05-24 | Plasmid dna preparations and methods for producing same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009538147A JP2009538147A (ja) | 2009-11-05 |
| JP2009538147A5 true JP2009538147A5 (enExample) | 2010-07-22 |
| JP5820564B2 JP5820564B2 (ja) | 2015-11-24 |
Family
ID=38542027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009512311A Active JP5820564B2 (ja) | 2006-05-24 | 2007-05-24 | プラスミドｄｎａ調製物およびそれらの作製方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7935505B2 (enExample) |
| EP (1) | EP2027272B1 (enExample) |
| JP (1) | JP5820564B2 (enExample) |
| DK (1) | DK2027272T3 (enExample) |
| WO (1) | WO2007140274A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102171341A (zh) * | 2008-04-30 | 2011-08-31 | 格兰达利斯有限公司 | 高纯度质粒dna制备物及其制备方法 |
| US11274292B2 (en) | 2011-03-29 | 2022-03-15 | Phynexus, Inc. | Devices and methods for plasmid purification |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5997881A (en) * | 1995-11-22 | 1999-12-07 | University Of Maryland, Baltimore | Method of making non-pyrogenic lipopolysaccharide or A |
| ES2195112T5 (es) * | 1996-02-06 | 2015-10-15 | Roche Diagnostics Gmbh | Procedimiento para la preparación de ácido nucleico purificado y el uso del mismo |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
-
2007
- 2007-05-24 DK DK07784120.3T patent/DK2027272T3/en active
- 2007-05-24 US US12/294,159 patent/US7935505B2/en active Active
- 2007-05-24 JP JP2009512311A patent/JP5820564B2/ja active Active
- 2007-05-24 EP EP07784120.3A patent/EP2027272B1/en active Active
- 2007-05-24 WO PCT/US2007/069685 patent/WO2007140274A1/en not_active Ceased
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