JP2009537534A5 - - Google Patents
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- Publication number
- JP2009537534A5 JP2009537534A5 JP2009511042A JP2009511042A JP2009537534A5 JP 2009537534 A5 JP2009537534 A5 JP 2009537534A5 JP 2009511042 A JP2009511042 A JP 2009511042A JP 2009511042 A JP2009511042 A JP 2009511042A JP 2009537534 A5 JP2009537534 A5 JP 2009537534A5
- Authority
- JP
- Japan
- Prior art keywords
- blood
- subject
- loss anemia
- blood loss
- substitute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000007502 Anemia Diseases 0.000 claims 2
- 230000037227 Blood Loss Effects 0.000 claims 2
- 230000001154 acute Effects 0.000 claims 2
- 239000003633 blood substitute Substances 0.000 claims 2
- 210000004369 Blood Anatomy 0.000 claims 1
- 102000003951 Erythropoietin Human genes 0.000 claims 1
- 108090000394 Erythropoietin Proteins 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 229940105423 erythropoietin Drugs 0.000 claims 1
- 230000001146 hypoxic Effects 0.000 claims 1
Claims (1)
- 対象における急性失血性貧血を治療するための方法であって、該対象において血液容量を増加させ、急性失血性貧血に伴う低酸素を抑えるのに有効な量の血液代替物を、それを必要とする対象に投与することを含み、該血液代替物は、酸素正常状態下で細胞培養において試験した場合、エリスロポエチンの発現を誘導する、前記方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/436,089 US7759306B2 (en) | 2006-05-16 | 2006-05-16 | Methods of treating acute blood loss |
PCT/US2007/011697 WO2007136641A2 (en) | 2006-05-16 | 2007-05-15 | Methods of treating acute blood loss anemia with a cross-linked hemoglobin blood substitute |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009537534A JP2009537534A (ja) | 2009-10-29 |
JP2009537534A5 true JP2009537534A5 (ja) | 2010-07-15 |
Family
ID=38565802
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009511042A Pending JP2009537534A (ja) | 2006-05-16 | 2007-05-15 | 急性失血の治療方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US7759306B2 (ja) |
EP (1) | EP2037953A2 (ja) |
JP (1) | JP2009537534A (ja) |
KR (1) | KR20090033329A (ja) |
CN (1) | CN101489581A (ja) |
AU (1) | AU2007254300A1 (ja) |
BR (1) | BRPI0711479A2 (ja) |
CA (1) | CA2657965A1 (ja) |
IL (1) | IL195312A0 (ja) |
MX (1) | MX2008014648A (ja) |
RU (1) | RU2008149514A (ja) |
WO (1) | WO2007136641A2 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10172950B2 (en) | 2009-06-09 | 2019-01-08 | Prolong Pharmaceuticals, LLC | Hemoglobin compositions |
US10172949B2 (en) | 2009-06-09 | 2019-01-08 | Prolong Pharmaceuticals, LLC | Hemoglobin compositions |
DK2440239T3 (en) | 2009-06-09 | 2017-10-16 | Prolong Pharmaceuticals Llc | HEMOGLOBIN FORMATIONS |
US7989593B1 (en) | 2010-05-27 | 2011-08-02 | Bing Lou Wong | Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof |
US8048856B1 (en) | 2010-06-23 | 2011-11-01 | Billion King, Ltd. | Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition |
US7932356B1 (en) | 2010-06-23 | 2011-04-26 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition |
US8084581B1 (en) | 2011-04-29 | 2011-12-27 | Bing Lou Wong | Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus |
US20130052232A1 (en) | 2011-08-31 | 2013-02-28 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking |
ES2651717B1 (es) * | 2016-07-26 | 2018-11-16 | Lara OLLER DUQUE | Solución acuosa cristaloide isotónica |
CN106620663B (zh) * | 2017-02-05 | 2020-05-19 | 中国医学科学院生物医学工程研究所 | 糖-血红蛋白纳米粒子的制备方法及用途 |
EP3655019A4 (en) | 2017-07-18 | 2021-04-21 | Virtech Bio, Inc. | BLUTER SUBSTITUTES CONTAINING HEMOGLOBIN AND PROCESS FOR THEIR PRODUCTION |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4831012A (en) | 1984-03-23 | 1989-05-16 | Baxter International Inc. | Purified hemoglobin solutions and method for making same |
US5281579A (en) | 1984-03-23 | 1994-01-25 | Baxter International Inc. | Purified virus-free hemoglobin solutions and method for making same |
US4598064A (en) | 1984-06-27 | 1986-07-01 | University Of Iowa Research Foundation | Alpha-alpha cross-linked hemoglobins |
US4600531A (en) | 1984-06-27 | 1986-07-15 | University Of Iowa Research Foundation | Production of alpha-alpha cross-linked hemoglobins in high yield |
US5194590A (en) | 1986-06-20 | 1993-03-16 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
US4826811A (en) | 1986-06-20 | 1989-05-02 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
US5464814A (en) | 1986-06-20 | 1995-11-07 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
US5753616A (en) | 1986-11-10 | 1998-05-19 | Biopure Corporation | Method for producing a stable polymerized hemoglobin blood-substitute |
US5084558A (en) | 1987-10-13 | 1992-01-28 | Biopure Corporation | Extra pure semi-synthetic blood substitute |
CA1312009C (en) | 1986-11-10 | 1992-12-29 | Carl W. Rausch | Extra pure semi-synthetic blood substitute |
GB8710598D0 (en) | 1987-05-05 | 1987-06-10 | Star Medical Diagnostics Ltd | Hemoglobin based blood substitute |
GB8711614D0 (en) | 1987-05-16 | 1987-06-24 | Medical Res Council | Proteins |
US6022849A (en) | 1987-05-16 | 2000-02-08 | Baxter Biotech Technology Saarl | Mutant recombinant hemoglobins containing heme pocket mutations |
US5449759A (en) | 1987-05-16 | 1995-09-12 | Somatogen, Inc. | Hemoglobins with intersubunit desulfide bonds |
US5439882A (en) | 1989-12-29 | 1995-08-08 | Texas Tech University Health Sciences Center | Blood substitute |
US5631219A (en) | 1994-03-08 | 1997-05-20 | Somatogen, Inc. | Method of stimulating hematopoiesis with hemoglobin |
US5895810A (en) | 1995-03-23 | 1999-04-20 | Biopure Corporation | Stable polymerized hemoglobin and use thereof |
AU733714B2 (en) | 1996-08-27 | 2001-05-24 | Hemosol Inc. | Enhanced stimulation of erythropoiesis |
EP1034267A1 (en) | 1997-12-04 | 2000-09-13 | Genzyme Corporation | Compositions and methods for inducing gene expression |
US6124131A (en) | 1998-08-25 | 2000-09-26 | The Johns Hopkins University School Of Medicine | Mutant hypoxia inducible factor-1 HIF-1 |
US6894150B1 (en) | 1999-10-01 | 2005-05-17 | Ross Walden Tye | Non-pyrogenic, endotoxin-free, stroma-free tetrameric hemoglobin |
US6849718B2 (en) | 2001-03-20 | 2005-02-01 | Dana Farber Cancer Institute, Inc. | Muteins of hypoxia inducible factor alpha and methods of use thereof |
US6838430B2 (en) | 2001-09-28 | 2005-01-04 | The Regents Of The University Of California | Use of HIF-1a variants to accelerate wound healing |
-
2006
- 2006-05-16 US US11/436,089 patent/US7759306B2/en not_active Expired - Fee Related
-
2007
- 2007-05-15 MX MX2008014648A patent/MX2008014648A/es not_active Application Discontinuation
- 2007-05-15 RU RU2008149514/15A patent/RU2008149514A/ru not_active Application Discontinuation
- 2007-05-15 KR KR1020087030641A patent/KR20090033329A/ko not_active Application Discontinuation
- 2007-05-15 EP EP07777086A patent/EP2037953A2/en not_active Withdrawn
- 2007-05-15 JP JP2009511042A patent/JP2009537534A/ja active Pending
- 2007-05-15 WO PCT/US2007/011697 patent/WO2007136641A2/en active Application Filing
- 2007-05-15 AU AU2007254300A patent/AU2007254300A1/en not_active Abandoned
- 2007-05-15 BR BRPI0711479-6A patent/BRPI0711479A2/pt not_active IP Right Cessation
- 2007-05-15 CN CNA2007800270704A patent/CN101489581A/zh active Pending
- 2007-05-15 CA CA002657965A patent/CA2657965A1/en not_active Abandoned
-
2008
- 2008-11-16 IL IL195312A patent/IL195312A0/en unknown
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