JP2009536021A - 関節リウマチの患者の末梢血白血球におけるFC受容体媒介性腫瘍壊死因子スーパーファミリ及びケモカインのmRNA発現の増大 - Google Patents

関節リウマチの患者の末梢血白血球におけるFC受容体媒介性腫瘍壊死因子スーパーファミリ及びケモカインのmRNA発現の増大 Download PDF

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JP2009536021A
JP2009536021A JP2009504310A JP2009504310A JP2009536021A JP 2009536021 A JP2009536021 A JP 2009536021A JP 2009504310 A JP2009504310 A JP 2009504310A JP 2009504310 A JP2009504310 A JP 2009504310A JP 2009536021 A JP2009536021 A JP 2009536021A
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sample
ratio
leukocytes
tnfsf
mrna
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JP2009536021A5 (enExample
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マサト ミツハシ
勝也 遠藤
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Resonac Corp
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Hitachi Chemical Co Ltd
Showa Denko Materials Co Ltd
Resonac Corp
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Microbiology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biotechnology (AREA)
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  • Veterinary Medicine (AREA)
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  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009504310A 2006-04-07 2007-04-05 関節リウマチの患者の末梢血白血球におけるFC受容体媒介性腫瘍壊死因子スーパーファミリ及びケモカインのmRNA発現の増大 Pending JP2009536021A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79051106P 2006-04-07 2006-04-07
PCT/US2007/008559 WO2007117589A2 (en) 2006-04-07 2007-04-05 Enhanced fc receptor-mediated tumor necrosis factor superfamily and chemokine mrna expression in peripheral blood leukocytes in patients with rheumatoid arthritis

Publications (2)

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JP2009536021A true JP2009536021A (ja) 2009-10-08
JP2009536021A5 JP2009536021A5 (enExample) 2010-01-07

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JP2009504310A Pending JP2009536021A (ja) 2006-04-07 2007-04-05 関節リウマチの患者の末梢血白血球におけるFC受容体媒介性腫瘍壊死因子スーパーファミリ及びケモカインのmRNA発現の増大

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US (1) US20090311684A1 (enExample)
JP (1) JP2009536021A (enExample)
WO (1) WO2007117589A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1776471B9 (en) * 2004-05-25 2013-12-18 Hitachi Chemical Company, Ltd. Method of measuring cancer susceptibility
JP4772055B2 (ja) * 2004-10-20 2011-09-14 日立化成工業株式会社 mRNAの定量により薬剤の投与を選定する方法
JP4945554B2 (ja) * 2005-04-28 2012-06-06 ヒタチ ケミカル リサーチ センター インコーポレイテッド 食物サプリメントに対する個体変動評価のモデルとしての全血におけるexvivo遺伝子発現
WO2009070442A2 (en) 2007-11-14 2009-06-04 Hitachi Chemical Co. Ltd. Fc receptor-mediated tumor necrosis factor superfamily mrna expression in peripheral blood leukocytes
US11028443B2 (en) 2015-08-31 2021-06-08 Showa Denko Materials Co., Ltd. Molecular methods for assessing urothelial disease
CN115851887A (zh) * 2022-08-08 2023-03-28 山西中医药大学 一种类风湿关节炎中趋化因子表达及定位的检测方法及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002066637A2 (en) * 2000-10-31 2002-08-29 Hitachi Chemical Research Center, Inc. Method for collecting and using nuclear mrna

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US4925572A (en) * 1987-10-20 1990-05-15 Pall Corporation Device and method for depletion of the leukocyte content of blood and blood components
US4880548A (en) * 1988-02-17 1989-11-14 Pall Corporation Device and method for separating leucocytes from platelet concentrate
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5491063A (en) * 1994-09-01 1996-02-13 Hoffmann-La Roche Inc. Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
PT938320E (pt) * 1996-03-26 2010-09-22 Michael S Kopreski Método que permite a utilização de arn extracelular extraído de plasma ou de soro para detectar, monitorizar ou avaliar o cancro
US5683698A (en) * 1996-08-02 1997-11-04 New England Deaconess Hospital Formulation for alleviating symptoms associated with arthritis
US7514232B2 (en) * 1996-12-06 2009-04-07 Becton, Dickinson And Company Method for detecting T cell response to specific antigens in whole blood
US20020006613A1 (en) * 1998-01-20 2002-01-17 Shyjan Andrew W. Methods and compositions for the identification and assessment of cancer therapies
US20020048566A1 (en) * 2000-09-14 2002-04-25 El-Deiry Wafik S. Modulation of cellular apoptosis and methods for treating cancer
US6993384B2 (en) * 2001-12-04 2006-01-31 Advanced Bionics Corporation Apparatus and method for determining the relative position and orientation of neurostimulation leads
US7745180B2 (en) * 2002-04-24 2010-06-29 Hitachi Chemical Co., Ltd. Device and method for high-throughput quantification of mRNA from whole blood
AU2002953533A0 (en) * 2002-12-24 2003-01-16 Arthron Limited Fc receptor modulating compounds and compositions
EP1776471B9 (en) * 2004-05-25 2013-12-18 Hitachi Chemical Company, Ltd. Method of measuring cancer susceptibility
JP4945554B2 (ja) * 2005-04-28 2012-06-06 ヒタチ ケミカル リサーチ センター インコーポレイテッド 食物サプリメントに対する個体変動評価のモデルとしての全血におけるexvivo遺伝子発現
US7935482B2 (en) * 2005-09-27 2011-05-03 Source Precision Medicine, Inc. Gene expression profiling for identification monitoring and treatment of rheumatoid arthritis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002066637A2 (en) * 2000-10-31 2002-08-29 Hitachi Chemical Research Center, Inc. Method for collecting and using nuclear mrna

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US20090311684A1 (en) 2009-12-17
WO2007117589A3 (en) 2008-11-27
WO2007117589A2 (en) 2007-10-18

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