JP2009535425A - 有機化合物の使用 - Google Patents

有機化合物の使用 Download PDF

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Publication number
JP2009535425A
JP2009535425A JP2009510039A JP2009510039A JP2009535425A JP 2009535425 A JP2009535425 A JP 2009535425A JP 2009510039 A JP2009510039 A JP 2009510039A JP 2009510039 A JP2009510039 A JP 2009510039A JP 2009535425 A JP2009535425 A JP 2009535425A
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JP
Japan
Prior art keywords
disease
diabetes
errγ
treatment
agonist
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Pending
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JP2009510039A
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Japanese (ja)
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JP2009535425A5 (https=
Inventor
シャミナ・エム・ラングワラ
スーザン・シー・スティーブンソン
ウ・ジダン
Original Assignee
ノバルティス アクチエンゲゼルシャフト
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38477124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2009535425(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2009535425A publication Critical patent/JP2009535425A/ja
Publication of JP2009535425A5 publication Critical patent/JP2009535425A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2009510039A 2006-05-03 2007-05-02 有機化合物の使用 Pending JP2009535425A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79722806P 2006-05-03 2006-05-03
PCT/US2007/067971 WO2007131005A2 (en) 2006-05-03 2007-05-02 Use of organic compounds

Publications (2)

Publication Number Publication Date
JP2009535425A true JP2009535425A (ja) 2009-10-01
JP2009535425A5 JP2009535425A5 (https=) 2010-06-24

Family

ID=38477124

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009510039A Pending JP2009535425A (ja) 2006-05-03 2007-05-02 有機化合物の使用

Country Status (13)

Country Link
US (1) US20090281191A1 (https=)
EP (1) EP2015777B1 (https=)
JP (1) JP2009535425A (https=)
KR (1) KR20090005137A (https=)
CN (1) CN101432024A (https=)
AT (1) ATE477819T1 (https=)
AU (1) AU2007248112A1 (https=)
BR (1) BRPI0711174A2 (https=)
CA (1) CA2649701A1 (https=)
DE (1) DE602007008553D1 (https=)
MX (1) MX2008014008A (https=)
RU (1) RU2008147269A (https=)
WO (1) WO2007131005A2 (https=)

Families Citing this family (29)

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Publication number Priority date Publication date Assignee Title
MX354217B (es) 2010-05-14 2018-02-19 Dana Farber Cancer Inst Inc Composiciones y metodos para el tratamiento de leucemia.
PL2902030T3 (pl) 2010-05-14 2017-07-31 Dana-Farber Cancer Institute, Inc. Związki tienotriazolodiazepinowe do leczenia nowotworu
CN103180318B (zh) 2010-05-14 2017-05-10 达那-法伯癌症研究所 雄性避孕组合物以及使用方法
US8962546B2 (en) * 2011-03-01 2015-02-24 Salk Institute For Biological Studies Modulation of estrogen receptor-related receptor gamma (ERRγ) and uses therefor
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US9714946B2 (en) 2013-03-14 2017-07-25 Dana-Farber Cancer Institute, Inc. Bromodomain binding reagents and uses thereof
EP3010587A4 (en) * 2013-06-18 2017-04-12 Salk Institute for Biological Studies Methods of treating muscular dystrophy
AU2014292888B2 (en) 2013-07-25 2018-03-22 Dana-Farber Cancer Institute, Inc. Inhibitors of transcription factors and uses thereof
CA2929652A1 (en) 2013-11-08 2015-05-14 Dana-Farber Cancer Institute, Inc. Combination therapy for cancer using bromodomain and extra-terminal (bet) protein inhibitors
BR112016017045A2 (pt) 2014-01-31 2017-08-08 Dana Farber Cancer Inst Inc Derivados de diazepano e usos dos mesmos
CA2936865A1 (en) 2014-01-31 2015-08-06 Dana-Farber Cancer Institute, Inc. Diaminopyrimidine benzenesulfone derivatives and uses thereof
WO2015117087A1 (en) 2014-01-31 2015-08-06 Dana-Farber Cancer Institute, Inc. Uses of diazepane derivatives
SG11201607108XA (en) 2014-02-28 2016-09-29 Tensha Therapeutics Inc Treatment of conditions associated with hyperinsulinaemia
EP3739041A1 (en) 2014-03-27 2020-11-18 The Salk Institute for Biological Studies Compositions and methods for treating type 1 and type 2 diabetes and related disorders
KR20170032474A (ko) * 2014-08-08 2017-03-22 다나-파버 캔서 인스티튜트 인크. 디히드로프테리디논 유도체 및 그의 용도
CN106715437A (zh) 2014-08-08 2017-05-24 达纳-法伯癌症研究所股份有限公司 二氮杂环庚烷衍生物及其用途
BR112017008714A2 (pt) 2014-10-27 2017-12-19 Tensha Therapeutics Inc inibidores de bromodomínio
AU2016225076B2 (en) 2015-02-27 2018-09-13 Salk Institute For Biological Studies Reprogramming progenitor compositions and methods of use therefore
US10702527B2 (en) 2015-06-12 2020-07-07 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
HK1256417A1 (zh) 2015-09-11 2019-09-20 达纳-法伯癌症研究所股份有限公司 氰基噻吩并三唑并二氮杂环庚三烯及其用途
RU2018112953A (ru) 2015-09-11 2019-10-14 Дана-Фарбер Кэнсер Инститьют, Инк. Ацетамидтиенотриазолодиазепины и пути их применения
WO2017053084A1 (en) * 2015-09-25 2017-03-30 Salk Institute For Biological Studies Estrogen related receptor gamma (erry) enhances and maintains brown fat thermogenic capacity
MX2018006499A (es) 2015-11-25 2018-08-01 Dana Farber Cancer Inst Inc Inhibidores de bromodominio bivalentes y usos de los mismos.
AU2017269364B2 (en) 2016-05-25 2023-08-31 Salk Institute For Biological Studies Compositions and methods for organoid generation and disease modeling

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005514921A (ja) * 2001-11-09 2005-05-26 ダナ−ファーバー キャンサー インスティチュート インク PGC−1β、新規PGC−1相同体およびその用途
EP1548434A1 (en) * 2002-08-08 2005-06-29 Japan Science and Technology Agency Method of screening drug

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050074765A1 (en) * 2002-10-16 2005-04-07 Blanchard Steven G. Methods for identifying and using modulators of estrogen related receptor gamma
WO2006130503A2 (en) * 2005-05-27 2006-12-07 Janssen Pharmaceutica N.V. Errϝ peptide fragment complexes and uses thereof in drug discovery

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005514921A (ja) * 2001-11-09 2005-05-26 ダナ−ファーバー キャンサー インスティチュート インク PGC−1β、新規PGC−1相同体およびその用途
EP1548434A1 (en) * 2002-08-08 2005-06-29 Japan Science and Technology Agency Method of screening drug

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6012032823; Kamei Y et al.: 'PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-e' Proc Natl Acad Sci U S A. Vol.100 No.21, 20031014, pp.12378-12383 *
JPN6012032825; Zuercher WJ et al.: 'Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists' J Med Chem. Vol.48 No.9, 20050505, pp.3107-3109 *
JPN6012032827; Hawley JA et al.: 'Strategies to enhance fat utilisation during exercise.' Sports Med. Vol.25 No.4, 199804, pp.241-257 *
JPN6012032829; Murase T et al.: 'Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice.' Am J Physiol Regul Integr Comp Physiol. Vol.288 No.3, 200503, pp.708-715 *

Also Published As

Publication number Publication date
EP2015777A2 (en) 2009-01-21
US20090281191A1 (en) 2009-11-12
WO2007131005A3 (en) 2008-06-19
MX2008014008A (es) 2009-03-25
BRPI0711174A2 (pt) 2011-08-23
DE602007008553D1 (de) 2010-09-30
WO2007131005A2 (en) 2007-11-15
AU2007248112A1 (en) 2007-11-15
CA2649701A1 (en) 2007-11-15
RU2008147269A (ru) 2010-06-10
KR20090005137A (ko) 2009-01-12
EP2015777B1 (en) 2010-08-18
ATE477819T1 (de) 2010-09-15
CN101432024A (zh) 2009-05-13

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