JP2009534297A5 - - Google Patents
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- JP2009534297A5 JP2009534297A5 JP2008558561A JP2008558561A JP2009534297A5 JP 2009534297 A5 JP2009534297 A5 JP 2009534297A5 JP 2008558561 A JP2008558561 A JP 2008558561A JP 2008558561 A JP2008558561 A JP 2008558561A JP 2009534297 A5 JP2009534297 A5 JP 2009534297A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- epitope
- amino acid
- acid residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78112106P | 2006-03-10 | 2006-03-10 | |
| US82827106P | 2006-10-05 | 2006-10-05 | |
| US86250106P | 2006-10-23 | 2006-10-23 | |
| PCT/US2007/063787 WO2007106769A2 (en) | 2006-03-10 | 2007-03-12 | Antibodies that bind both il-17a and il-17f and methods of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009534297A JP2009534297A (ja) | 2009-09-24 |
| JP2009534297A5 true JP2009534297A5 (https=) | 2009-11-05 |
Family
ID=38510202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558561A Pending JP2009534297A (ja) | 2006-03-10 | 2007-03-12 | Il−17aおよびil−17fの両方に結合する抗体ならびにその使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (8) | US20070218065A1 (https=) |
| EP (2) | EP1996622A2 (https=) |
| JP (1) | JP2009534297A (https=) |
| AU (1) | AU2007226627B2 (https=) |
| CA (1) | CA2646478A1 (https=) |
| IL (1) | IL193444A (https=) |
| WO (1) | WO2007106769A2 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2784084B2 (en) | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| US7790862B2 (en) | 2006-06-13 | 2010-09-07 | Zymogenetics, Inc. | IL-17 and IL-23 antagonists and methods of using the same |
| US7790163B2 (en) | 2006-03-10 | 2010-09-07 | Zymogenetics, Inc. | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
| EP1996622A2 (en) | 2006-03-10 | 2008-12-03 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
| US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| GB0612928D0 (en) | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
| EP2046835B1 (en) | 2006-08-11 | 2011-10-26 | Schering Corporation | Antibodies to il-17a |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| EP2150564A2 (en) | 2007-04-27 | 2010-02-10 | ZymoGenetics, Inc. | Antagonists to il-17a, il-17f, and il-23p19 and methods of use |
| JP5116842B2 (ja) * | 2007-04-27 | 2013-01-09 | ザイモジェネティクス, インコーポレイテッド | IL−17AおよびIl−17Fの両方に結合する抗体ならびにそれを使用する方法 |
| US20100239590A1 (en) * | 2007-06-20 | 2010-09-23 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
| GB0807413D0 (en) | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| RU2474588C2 (ru) * | 2008-05-05 | 2013-02-10 | Новиммун Са | Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения |
| KR20110048536A (ko) * | 2008-08-28 | 2011-05-11 | 와이어쓰 엘엘씨 | 자가면역 질병에서 il-22, il-17 및 il-1 패밀리 시토킨의 용도 |
| US8790642B2 (en) * | 2008-08-29 | 2014-07-29 | Genentech, Inc. | Cross-reactive and bispecific anti-IL-17A/F antibodies |
| CN102458437B (zh) | 2009-05-05 | 2015-06-10 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
| MX2012002428A (es) * | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| US20130064788A1 (en) * | 2009-10-10 | 2013-03-14 | Eleven Biotherapeutics, Inc. | Il-17 family cytokine compositions and uses |
| EP2493506B1 (en) | 2009-10-30 | 2019-04-10 | Janssen Biotech, Inc. | Il-17a antagonists |
| GB201100282D0 (en) | 2011-01-07 | 2011-02-23 | Ucb Pharma Sa | Biological methods |
| US10208349B2 (en) * | 2011-01-07 | 2019-02-19 | Ucb Biopharma Sprl | Lipocalin 2 as a biomarker for IL-17 inhibitor therapy efficacy |
| ME02734B (me) | 2011-01-14 | 2017-10-20 | Ucb Biopharma Sprl | Antitelo koje vezuje il-17a i il-17f |
| WO2013098420A1 (en) * | 2011-12-28 | 2013-07-04 | Immunoqure Ag | Method of isolating human antibodies |
| US8945553B2 (en) * | 2012-05-22 | 2015-02-03 | Bristol-Myers Squibb Company | Bispecific antibodies to IL-23 and IL-17A/F |
| LT2953969T (lt) | 2013-02-08 | 2019-12-10 | Novartis Ag | Anti-il-17a antikūnai ir jų panaudojimas autoimuninių ir uždegiminių ligų gydymui |
| RU2577228C2 (ru) * | 2014-03-14 | 2016-03-10 | Закрытое Акционерное Общество "Биокад" | Анти-il-17-антитела, способ их получения и способ применения |
| TWI713453B (zh) | 2014-06-23 | 2020-12-21 | 美商健生生物科技公司 | 干擾素α及ω抗體拮抗劑 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| EP3322716B1 (en) * | 2015-07-15 | 2025-02-12 | California Institute of Technology | Il-17f-specific capture agents and methods of using |
| CN116059350A (zh) * | 2015-10-27 | 2023-05-05 | Ucb生物制药有限责任公司 | 使用抗-il-17a/f抗体的治疗方法 |
| CN107488227A (zh) * | 2016-06-12 | 2017-12-19 | 三生国健药业(上海)股份有限公司 | 抗人白细胞介素‑17a单克隆抗体、其制备方法和应用 |
| ES2905917T3 (es) | 2016-09-14 | 2022-04-12 | Beijing Hanmi Pharmaceutical Co Ltd | Anticuerpo que se une específicamente a IL-17A y fragmento funcional del mismo |
| US10858427B2 (en) | 2017-03-10 | 2020-12-08 | Suzhou Kanova Biopharmaceutical Co., Ltd. | Monoclonal antibody against both IL-17A and IL-17F and use of the same |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4603044A (en) | 1983-01-06 | 1986-07-29 | Technology Unlimited, Inc. | Hepatocyte Directed Vesicle delivery system |
| US4694778A (en) | 1984-05-04 | 1987-09-22 | Anicon, Inc. | Chemical vapor deposition wafer boat |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| EP0281604B1 (en) | 1986-09-02 | 1993-03-31 | Enzon Labs Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US6010902A (en) | 1988-04-04 | 2000-01-04 | Bristol-Meyers Squibb Company | Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| DE3909708A1 (de) | 1989-03-23 | 1990-09-27 | Boehringer Mannheim Gmbh | Verfahren zur herstellung bispezifischer antikoerper |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5582996A (en) | 1990-12-04 | 1996-12-10 | The Wistar Institute Of Anatomy & Biology | Bifunctional antibodies and method of preparing same |
| JP3202999B2 (ja) | 1991-01-31 | 2001-08-27 | 協和醗酵工業株式会社 | 肝移行性リポソーム製剤 |
| DE4118120A1 (de) | 1991-06-03 | 1992-12-10 | Behringwerke Ag | Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung |
| ATE207080T1 (de) | 1991-11-25 | 2001-11-15 | Enzon Inc | Multivalente antigen-bindende proteine |
| US6562333B1 (en) | 1993-06-14 | 2003-05-13 | Schering Corporation | Purified mammalian CTLA-8 antigens and related reagents |
| US6274711B1 (en) * | 1993-06-14 | 2001-08-14 | Inserm, Institut National De La Sante Et De La Recherche Medicale | Purified mammalian CTLA-8 antigens and related reagents |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US6902735B1 (en) | 1995-07-19 | 2005-06-07 | Genetics Institute, Llc | Antibodies to human IL-17F and other CTLA-8-related proteins |
| DE69634726T2 (de) | 1995-07-19 | 2006-05-04 | Genetics Institute, LLC, Cambridge | Menschliche ctla-8 und verwendung von ctla-8 ähnlichen proteinen |
| US6063372A (en) | 1995-10-27 | 2000-05-16 | Inserm, Institut National De La Sante Et De La Recherche Medicale | Uses of mammalian CTLA-8 and related reagents |
| DE69623316T2 (de) | 1995-10-27 | 2003-04-17 | Institut National De La Sante Et De La Recherche Medicale I.N.S.E.R.M., Paris | Ctla-8 in kombination mit g-csf oder mit g-csf und il-6, und verwendung vom ctla-8 zur behandlung von infektionen |
| DE19541844C1 (de) | 1995-11-09 | 1997-07-24 | Gsf Forschungszentrum Umwelt | Verfahren zur Herstellung von menschlichen Antikörpern und deren Verwendung |
| EP2784084B2 (en) * | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| HUE026260T2 (en) | 2003-11-21 | 2016-06-28 | Ucb Biopharma Sprl | A method for treating multiple sclerosis by inhibiting IL-17 activity |
| US7910540B2 (en) * | 2004-06-10 | 2011-03-22 | Zymogenetics, Inc. | Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation |
| GB0425569D0 (en) | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Biological products |
| GT200600065A (es) * | 2005-02-14 | 2006-10-02 | Anticuerpos para interleucina-17f y otros antagonistas de la señalizacion de il-17f y sus usos | |
| DE102005026436B4 (de) | 2005-06-08 | 2022-08-18 | Austriamicrosystems Ag | Schnittstellenanordnung, insbesondere für ein System-on-Chip, und deren Verwendung |
| JP5054914B2 (ja) * | 2005-11-14 | 2012-10-24 | 日本ゼトック株式会社 | 口腔用組成物 |
| EP1963368B3 (en) | 2005-12-13 | 2020-06-10 | Eli Lilly And Company | Anti-il-17 antibodies |
| US7910703B2 (en) * | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| EP1996622A2 (en) * | 2006-03-10 | 2008-12-03 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
| US7790163B2 (en) | 2006-03-10 | 2010-09-07 | Zymogenetics, Inc. | Antibodies that bind both IL-17A and IL-17F and methods of using the same |
| TW200815469A (en) * | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
| EP2046835B1 (en) | 2006-08-11 | 2011-10-26 | Schering Corporation | Antibodies to il-17a |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| JP5116842B2 (ja) | 2007-04-27 | 2013-01-09 | ザイモジェネティクス, インコーポレイテッド | IL−17AおよびIl−17Fの両方に結合する抗体ならびにそれを使用する方法 |
| ES2602610T3 (es) | 2007-05-31 | 2017-02-21 | Medigene Ag | Proteína estructural mutada de un parvovirus |
| US8945553B2 (en) | 2012-05-22 | 2015-02-03 | Bristol-Myers Squibb Company | Bispecific antibodies to IL-23 and IL-17A/F |
-
2007
- 2007-03-12 EP EP07800147A patent/EP1996622A2/en not_active Withdrawn
- 2007-03-12 WO PCT/US2007/063787 patent/WO2007106769A2/en not_active Ceased
- 2007-03-12 EP EP11163676A patent/EP2377887A1/en not_active Withdrawn
- 2007-03-12 JP JP2008558561A patent/JP2009534297A/ja active Pending
- 2007-03-12 US US11/684,907 patent/US20070218065A1/en not_active Abandoned
- 2007-03-12 AU AU2007226627A patent/AU2007226627B2/en not_active Ceased
- 2007-03-12 CA CA002646478A patent/CA2646478A1/en not_active Abandoned
-
2008
- 2008-08-14 IL IL193444A patent/IL193444A/en not_active IP Right Cessation
-
2009
- 2009-11-12 US US12/617,078 patent/US20110097331A1/en not_active Abandoned
-
2011
- 2011-08-05 US US13/198,933 patent/US20110318350A1/en not_active Abandoned
-
2012
- 2012-02-02 US US13/364,810 patent/US20120177653A1/en not_active Abandoned
-
2013
- 2013-03-26 US US13/850,403 patent/US20130209470A1/en not_active Abandoned
-
2015
- 2015-11-04 US US14/932,193 patent/US9663572B2/en active Active
-
2017
- 2017-04-28 US US15/581,877 patent/US10023656B2/en active Active
-
2018
- 2018-06-15 US US16/009,653 patent/US10640575B2/en active Active
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