JP2008516985A5 - - Google Patents
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- Publication number
- JP2008516985A5 JP2008516985A5 JP2007537014A JP2007537014A JP2008516985A5 JP 2008516985 A5 JP2008516985 A5 JP 2008516985A5 JP 2007537014 A JP2007537014 A JP 2007537014A JP 2007537014 A JP2007537014 A JP 2007537014A JP 2008516985 A5 JP2008516985 A5 JP 2008516985A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- antibody
- zcytor21
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 25
- 229920001184 polypeptide Polymers 0.000 claims 23
- 102000004196 processed proteins & peptides Human genes 0.000 claims 23
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 11
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 11
- 125000000539 amino acid group Chemical group 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000003550 marker Substances 0.000 claims 4
- 102000013691 Interleukin-17 Human genes 0.000 claims 3
- 108050003558 Interleukin-17 Proteins 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 208000027866 inflammatory disease Diseases 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 230000001154 acute effect Effects 0.000 claims 2
- 239000005557 antagonist Substances 0.000 claims 2
- 208000037976 chronic inflammation Diseases 0.000 claims 2
- 208000037893 chronic inflammatory disorder Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000006249 magnetic particle Substances 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 230000006320 pegylation Effects 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000037487 Endotoxemia Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 206010040070 Septic Shock Diseases 0.000 claims 1
- 206010044248 Toxic shock syndrome Diseases 0.000 claims 1
- 231100000650 Toxic shock syndrome Toxicity 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 229940126619 mouse monoclonal antibody Drugs 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61965104P | 2004-10-18 | 2004-10-18 | |
| US62220704P | 2004-10-25 | 2004-10-25 | |
| PCT/US2005/037332 WO2006044840A2 (en) | 2004-10-18 | 2005-10-18 | Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008516985A JP2008516985A (ja) | 2008-05-22 |
| JP2008516985A5 true JP2008516985A5 (https=) | 2008-12-11 |
Family
ID=36090952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007537014A Pending JP2008516985A (ja) | 2004-10-18 | 2005-10-18 | 可溶性ｚｃｙｔｏｒ２１、抗ｚｃｙｔｏｒ２１抗体及び結合パートナー、並びに炎症における使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20060142192A1 (https=) |
| EP (1) | EP1802657A2 (https=) |
| JP (1) | JP2008516985A (https=) |
| KR (1) | KR20070084330A (https=) |
| AU (1) | AU2005295421A1 (https=) |
| BR (1) | BRPI0516603A (https=) |
| CA (1) | CA2584078A1 (https=) |
| EA (1) | EA200700823A1 (https=) |
| IL (1) | IL182186A0 (https=) |
| MX (1) | MX2007004597A (https=) |
| NO (1) | NO20072514L (https=) |
| WO (1) | WO2006044840A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040197306A1 (en) * | 2000-05-24 | 2004-10-07 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
| BRPI0516603A (pt) * | 2004-10-18 | 2008-09-16 | Zymogenetics Inc | receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos para tratar uma doença imuno-mediada em um paciente em necessidade de tal tratamento, para reduzir a inflamação mediada pela il-17c, para tratar um mamìfero afligido com uma doença inflamatória, e para tratar uma condição patológica em um paciente associada com a atividade de zcytor21 |
| WO2007047738A1 (en) * | 2005-10-18 | 2007-04-26 | Zymogenetics, Inc. | Il-17c antagonists and methods of using the same |
| EP2064237A2 (en) * | 2006-10-18 | 2009-06-03 | ZymoGenetics, Inc. | Il-17c antagonists and methods of using the same |
| AU2012324895B2 (en) * | 2011-10-19 | 2017-03-16 | Galapagos Nv | Antagonists of IL17C for the treatment of inflammatory disorders |
| JP2018529704A (ja) * | 2015-10-05 | 2018-10-11 | モルフォシス・アーゲー | アトピー性皮膚炎の治療および／または予防のためのｉｌ−１７ｃの拮抗剤 |
| CA3014842A1 (en) | 2016-02-19 | 2017-08-24 | Morphosys Ag | Antibodies for il-17c |
| IL309179A (en) * | 2021-06-10 | 2024-02-01 | Janssen Biotech Inc | Nucleic acid coding for KLK2-GPI fusion protein, recombinant cells and their uses |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ306653A (en) * | 1995-03-23 | 1999-03-29 | Immunex Corp | Isolated dna il-17 receptors |
| US6579520B2 (en) * | 1998-05-15 | 2003-06-17 | Genentech, Inc. | IL-17 related mammalian cytokine polypeptides (IL-17E) |
| US20020177188A1 (en) * | 1998-05-15 | 2002-11-28 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US6569645B2 (en) * | 1999-05-14 | 2003-05-27 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| CN1444652A (zh) * | 2000-05-24 | 2003-09-24 | 先灵公司 | 哺乳动物受体蛋白;相关试剂和方法 |
| US20040197306A1 (en) * | 2000-05-24 | 2004-10-07 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
| US20030096969A1 (en) * | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| EP1572883A2 (en) * | 2001-07-09 | 2005-09-14 | ZymoGenetics, Inc. | Human cytokine receptor |
| BRPI0516603A (pt) * | 2004-10-18 | 2008-09-16 | Zymogenetics Inc | receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos para tratar uma doença imuno-mediada em um paciente em necessidade de tal tratamento, para reduzir a inflamação mediada pela il-17c, para tratar um mamìfero afligido com uma doença inflamatória, e para tratar uma condição patológica em um paciente associada com a atividade de zcytor21 |
| WO2007047738A1 (en) * | 2005-10-18 | 2007-04-26 | Zymogenetics, Inc. | Il-17c antagonists and methods of using the same |
-
2005
- 2005-10-18 BR BRPI0516603-9A patent/BRPI0516603A/pt not_active IP Right Cessation
- 2005-10-18 JP JP2007537014A patent/JP2008516985A/ja active Pending
- 2005-10-18 KR KR1020077011257A patent/KR20070084330A/ko not_active Withdrawn
- 2005-10-18 MX MX2007004597A patent/MX2007004597A/es not_active Application Discontinuation
- 2005-10-18 US US11/253,200 patent/US20060142192A1/en not_active Abandoned
- 2005-10-18 EA EA200700823A patent/EA200700823A1/ru unknown
- 2005-10-18 EP EP05818898A patent/EP1802657A2/en not_active Withdrawn
- 2005-10-18 AU AU2005295421A patent/AU2005295421A1/en not_active Abandoned
- 2005-10-18 CA CA002584078A patent/CA2584078A1/en not_active Abandoned
- 2005-10-18 WO PCT/US2005/037332 patent/WO2006044840A2/en not_active Ceased
-
2006
- 2006-10-04 US US11/538,561 patent/US20070049525A1/en not_active Abandoned
- 2006-10-04 US US11/538,549 patent/US20070049524A1/en not_active Abandoned
-
2007
- 2007-03-26 IL IL182186A patent/IL182186A0/en unknown
- 2007-05-16 NO NO20072514A patent/NO20072514L/no not_active Application Discontinuation
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