JP2009532457A5 - - Google Patents

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Publication number
JP2009532457A5
JP2009532457A5 JP2009503689A JP2009503689A JP2009532457A5 JP 2009532457 A5 JP2009532457 A5 JP 2009532457A5 JP 2009503689 A JP2009503689 A JP 2009503689A JP 2009503689 A JP2009503689 A JP 2009503689A JP 2009532457 A5 JP2009532457 A5 JP 2009532457A5
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JP
Japan
Prior art keywords
pharmaceutical composition
compound
effective amount
cancer
biological condition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2009503689A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009532457A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2007/003143 external-priority patent/WO2008035206A2/en
Publication of JP2009532457A publication Critical patent/JP2009532457A/ja
Publication of JP2009532457A5 publication Critical patent/JP2009532457A5/ja
Ceased legal-status Critical Current

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JP2009503689A 2006-04-06 2007-04-06 ２−メチレン−１α−ヒドロキシ−１８，１９，２１−トリノルビタミンＤ３類縁体およびその使用 Ceased JP2009532457A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74438106P 2006-04-06 2006-04-06
PCT/IB2007/003143 WO2008035206A2 (en) 2006-04-06 2007-04-06 2-methylene-1 alpha-hydroxy-18,19,21-trinorvitamin d3 analogs and uses thereof

Publications (2)

Publication Number Publication Date
JP2009532457A JP2009532457A (ja) 2009-09-10
JP2009532457A5 true JP2009532457A5 (enExample) 2010-05-20

Family

ID=39200903

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009503689A Ceased JP2009532457A (ja) 2006-04-06 2007-04-06 ２−メチレン−１α−ヒドロキシ−１８，１９，２１−トリノルビタミンＤ３類縁体およびその使用

Country Status (8)

Country Link
US (1) US8575136B2 (enExample)
EP (1) EP2001841B1 (enExample)
JP (1) JP2009532457A (enExample)
AU (1) AU2007298651A1 (enExample)
CA (1) CA2645185A1 (enExample)
MX (1) MX2008012672A (enExample)
NZ (1) NZ570712A (enExample)
WO (1) WO2008035206A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8575136B2 (en) 2006-04-06 2013-11-05 Wisconsin Alumni Research Foundation 2-methylene-1α-hydroxy-18,19,21-trinorvitamin D3 analogs and uses thereof

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188345A (en) 1978-07-26 1980-02-12 Wisconsin Alumni Research Foundation Fluorovitamin D compounds and processes for their preparation
US4411833A (en) 1982-05-26 1983-10-25 Wisconsin Alumni Research Foundation Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol
US4666634A (en) 1984-12-05 1987-05-19 Chugai Seiyaku Kabushiki Kaisha vitamin D3 derivatives having a substituent at 2-position
US4970203A (en) 1988-12-09 1990-11-13 Deluca Hector F Method for improving reproductive functions in mammals
US5086191A (en) 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
JP2898882B2 (ja) 1993-04-05 1999-06-02 ウイスコンシン アラムナイ リサーチ フオンデーシヨン ２−位に置換基を有する１９−ノル−ビタミンｄ３ 化合物
US5880114A (en) 1993-06-16 1999-03-09 Wisconsin Alumni Research Foundation Treatment of immune deficiency with vitamin D compounds
US6291444B1 (en) 1993-06-16 2001-09-18 Wisconsin Alumni Research Foundation Treatment of t-cell immunodeficiencies with vitamin D compounds
US5552392A (en) 1993-11-03 1996-09-03 Wisconsin Alumni Research Foundation Method of treating hypoparathyroidism with (20S) vitamin D compounds
US5825133A (en) * 1996-09-25 1998-10-20 Rockwell International Resonant inverter for hot cathode fluorescent lamps
US6306844B1 (en) 1997-03-17 2001-10-23 Wisconsin Alumni Research Foundation Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US6392071B1 (en) 1997-03-17 2002-05-21 Wisconsin Alumni: Research Foundation 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
US5945410A (en) 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US5843928A (en) 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
US6382071B1 (en) 2000-08-07 2002-05-07 Gilbert A. Bertani Bola capturing apparatus
BR0113703A (pt) 2000-09-08 2003-07-22 Wisconsin Alumni Researcg Foun Compostos e métodos de tratamento de psorìase, leucemia, câncer do cólon, do seio ou da próstata, osteodistrofia renal, de doenças auto-imune, inflamatória e de condição de pele
US20030018017A1 (en) 2001-01-25 2003-01-23 Deluca Hector F. Method of treatment of type I diabetes
US6627622B2 (en) 2002-02-18 2003-09-30 Wisconsin Alumni Research Foundation (20S)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol and its uses
PT1453798E (pt) * 2001-12-13 2009-01-23 Wisconsin Alumni Res Found (20s)-1alfa-hidroxi-2-metileno-19-nor-bishomopregnacalciferol e suas utilizações
US6566352B1 (en) 2002-02-18 2003-05-20 Wisconsin Alumni Research Foudation 1 α-hydroxy-2-methylene-19-nor-pregnacalciferol and its uses
US6846811B2 (en) 2002-04-22 2005-01-25 Wisconsin Alumni Research Foundation (20S) 1α-hydroxy-2α-methyl and 2β-methyl-19-nor-vitamin D3 and their uses
KR20050120787A (ko) 2003-04-10 2005-12-23 위스콘신 얼럼나이 리서어치 화운데이션 2-프로필리덴-19-노르-비타민 ｄ 화합물
US20050009792A1 (en) 2003-07-08 2005-01-13 Deluca Hector F. (20S)-1alpha-hydroxy-2-methylene-19-nor-vitamin D3 and its uses
WO2005051396A2 (en) * 2003-11-25 2005-06-09 Deltanoid Pharmaceuticals, Inc. Methods for reducing body fat using vitamin d compounds
CA2544502A1 (en) 2003-11-25 2005-06-09 Wisconsin Alumni Research Foundation Vitamin d analogs for obesity prevention and treatment
US7713951B2 (en) * 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
WO2006057884A2 (en) * 2004-11-22 2006-06-01 Wisconsin Alumni Research Foundation 2α-METHYL AND 2ß-METHYL ANALOGS OF 19,26,27-TRINOR-(20S)-1α-HYDROXYVITAMIN D3 AND THEIR USES
US7803789B2 (en) 2006-02-02 2010-09-28 Wisconsin Alumni Research Foundation Vitamin D analog—RAK, methods and uses thereof
US7528122B2 (en) 2006-02-02 2009-05-05 Wisconsin Alumni Research Foundation Vitamin D analog—NEL, methods and uses thereof
US8193169B2 (en) * 2006-04-06 2012-06-05 Wisconsin Alumni Research Foundation (20R)-2α-methyl-19,26,2-trinor-vitamin D analogs
MX2008012673A (es) * 2006-04-06 2008-10-15 Wisconsin Alumni Res Found Analogos de 2-metilen-1a-hidroxi-19, 21-dinorvitamina d3 y sus usos.
US8575136B2 (en) 2006-04-06 2013-11-05 Wisconsin Alumni Research Foundation 2-methylene-1α-hydroxy-18,19,21-trinorvitamin D3 analogs and uses thereof
EP2247563A1 (en) * 2008-01-22 2010-11-10 Wisconsin Alumni Research Foundation 13,13-dimethyl-des-c,d analogs of 1alpha, 25-dihydroxy-19-nor-vitamin d3 compounds and topical composition dosage forms and methods of treating skin conditions thereof
US8193170B2 (en) * 2008-07-10 2012-06-05 Wisconsin Alumni Research Foundation 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs
US8399439B2 (en) * 2008-07-10 2013-03-19 Wisconsin Alumni Research Foundation 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs
WO2012151420A1 (en) * 2011-05-03 2012-11-08 Wisconsin Alumni Research Foundation 2α-METHYL AND 2β-METHYL ANALOGS OF 19,26-DINOR-1α, 25-DIHYDROXYVITAMIN D3 AND THEIR USES

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