JP2009532053A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009532053A5 JP2009532053A5 JP2009503661A JP2009503661A JP2009532053A5 JP 2009532053 A5 JP2009532053 A5 JP 2009532053A5 JP 2009503661 A JP2009503661 A JP 2009503661A JP 2009503661 A JP2009503661 A JP 2009503661A JP 2009532053 A5 JP2009532053 A5 JP 2009532053A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- sequence
- cell
- molecule
- cytidine deaminase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79027306P | 2006-04-07 | 2006-04-07 | |
| GBGB0607063.5A GB0607063D0 (en) | 2006-04-07 | 2006-04-07 | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
| US79794206P | 2006-05-05 | 2006-05-05 | |
| GBGB0623644.2A GB0623644D0 (en) | 2006-04-07 | 2006-11-27 | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
| PCT/GB2007/001304 WO2007128982A2 (en) | 2006-04-07 | 2007-04-10 | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009532053A JP2009532053A (ja) | 2009-09-10 |
| JP2009532053A5 true JP2009532053A5 (enExample) | 2010-05-27 |
Family
ID=36539563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009503661A Pending JP2009532053A (ja) | 2006-04-07 | 2007-04-10 | インヴィヴォでの核酸配列のエピジェネティック修飾用組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8298529B2 (enExample) |
| EP (1) | EP2010660B1 (enExample) |
| JP (1) | JP2009532053A (enExample) |
| GB (2) | GB0607063D0 (enExample) |
| WO (1) | WO2007128982A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2274430T3 (pl) * | 2008-04-30 | 2017-09-29 | Sanbio Inc | Komórki regenerujące nerwy ze zmianami w metylacji DNA |
| EP2128259A1 (en) * | 2008-05-27 | 2009-12-02 | Koninklijke Philips Electronics N.V. | Therapy delivery and monitoring using a gene of interest-reporter fusion protein and optical imaging |
| WO2010113039A1 (en) * | 2009-04-03 | 2010-10-07 | Medical Research Council | Mutants of activation-induced cytidine deaminase (aid) and methods of use |
| EP2258858A1 (en) * | 2009-06-05 | 2010-12-08 | Universitätsklinikum Freiburg | Transgenic LSD1 animal model for cancer |
| US20110104787A1 (en) * | 2009-11-05 | 2011-05-05 | President And Fellows Of Harvard College | Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences |
| JP2013514779A (ja) * | 2009-12-18 | 2013-05-02 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | 脱メチル化および細胞の再プログラミングを促進するためのシチジンデアミナーゼ関連薬剤の使用 |
| US20140274812A1 (en) | 2011-07-15 | 2014-09-18 | The General Hospital Corporation | Methods of Transcription Activator Like Effector Assembly |
| US9890364B2 (en) | 2012-05-29 | 2018-02-13 | The General Hospital Corporation | TAL-Tet1 fusion proteins and methods of use thereof |
| EP2906602B1 (en) | 2012-10-12 | 2019-01-16 | The General Hospital Corporation | Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins |
| CA2900338C (en) | 2013-02-07 | 2024-11-05 | The General Hospital Corporation | TRANSCRIPTIONAL ACTIVATORS TALE |
| US9721248B2 (en) | 2014-03-04 | 2017-08-01 | Bank Of America Corporation | ATM token cash withdrawal |
| GB201418965D0 (enExample) | 2014-10-24 | 2014-12-10 | Ospedale San Raffaele And Fond Telethon | |
| US10460367B2 (en) | 2016-04-29 | 2019-10-29 | Bank Of America Corporation | System for user authentication based on linking a randomly generated number to the user and a physical item |
| US10268635B2 (en) | 2016-06-17 | 2019-04-23 | Bank Of America Corporation | System for data rotation through tokenization |
| EP3562946B1 (en) * | 2016-12-28 | 2021-11-24 | Transgene SA | Oncolytic viruses and therapeutic molecules |
| GB2587970B (en) | 2018-04-19 | 2023-02-08 | Univ California | Compositions and methods for gene editing |
| EP3841204A4 (en) * | 2018-08-23 | 2022-05-18 | Sangamo Therapeutics, Inc. | CHANGED TARGET SPECIFIC BASE EDITORS |
| JP7059965B2 (ja) | 2019-02-21 | 2022-04-26 | 株式会社豊田中央研究所 | エピゲノム状態を制御する融合タンパク質及びその利用 |
| US11680109B2 (en) | 2019-05-29 | 2023-06-20 | Duke University | Compositions and methods for detection and measurement of RNA modifications through targeted RNA editing |
| CN113383749B (zh) * | 2020-03-12 | 2025-11-18 | 中国医学科学院基础医学研究所 | 一种使用单个肿瘤细胞构建小鼠肿瘤模型的方法 |
| JP7823919B2 (ja) * | 2021-05-20 | 2026-03-04 | 国立大学法人群馬大学 | エピゲノムが改変された動植物の親系統の製造に用いるための組成物およびその用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2646438B1 (fr) | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
| CA2276306C (en) * | 1996-12-30 | 2009-12-15 | The Johns Hopkins University School Of Medicine | Loss of imprinting-based in vitro diagnostic method to determine the propensity to develop cancer |
| US6534261B1 (en) * | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| CA2365601A1 (en) * | 1999-03-29 | 2000-10-05 | Kansai Technology Licensing Organization Co., Ltd. | Novel cytidine deaminase |
| AUPQ655100A0 (en) * | 2000-03-29 | 2000-04-20 | Am Asset Management Pty Ltd | Device and method for cleaning golf balls |
| ATE353361T1 (de) * | 2000-04-28 | 2007-02-15 | Sangamo Biosciences Inc | Gezielten modifikation der chromatinstruktur |
| EP1303608A2 (en) | 2000-07-21 | 2003-04-23 | Syngenta Participations AG | Zinc finger domain recognition code and uses thereof |
| AU2884102A (en) * | 2000-12-07 | 2002-06-18 | Sangamo Biosciences Inc | Regulation of angiogenesis with zinc finger proteins |
| JP2005508885A (ja) * | 2001-07-31 | 2005-04-07 | ザ ステイト オブ オレゴン， アクティング バイ アンド スルー ザ ステイト ボード オブ ハイヤー エデュケイション オン ビハーフ オブ ザ ユニバーシティー オブ オレゴン | Ｄｎａメチル化の阻害剤 |
| EP1506288B1 (en) * | 2002-05-10 | 2013-04-17 | Medical Research Council | Activation induced deaminase (aid) |
| GB0312676D0 (en) | 2003-06-02 | 2003-07-09 | Babraham Inst | Binding assay |
| FR2875239B1 (fr) * | 2004-09-10 | 2007-07-20 | Inst Necker Ass Loi De 1901 | Procede pour l'acceleration des mutations somatiques et son application en proteomique |
-
2006
- 2006-04-07 GB GBGB0607063.5A patent/GB0607063D0/en not_active Ceased
- 2006-11-27 GB GBGB0623644.2A patent/GB0623644D0/en not_active Ceased
-
2007
- 2007-04-10 US US12/226,094 patent/US8298529B2/en not_active Expired - Fee Related
- 2007-04-10 WO PCT/GB2007/001304 patent/WO2007128982A2/en not_active Ceased
- 2007-04-10 JP JP2009503661A patent/JP2009532053A/ja active Pending
- 2007-04-10 EP EP07732348.3A patent/EP2010660B1/en not_active Not-in-force
-
2012
- 2012-10-05 US US13/646,008 patent/US8658393B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107794272B (zh) | 一种高特异性的crispr基因组编辑体系 | |
| Zhong et al. | CRISPR-Cas9-mediated genetic screening in mice with haploid embryonic stem cells carrying a guide RNA library | |
| CN107208078B (zh) | 使用成对向导rna进行靶向遗传修饰的方法和组合物 | |
| CN105463027A (zh) | 一种高肌肉量及肥厚型心肌病模型克隆猪的制备方法 | |
| US20230125704A1 (en) | Modified bacterial retroelement with enhanced dna production | |
| JP7063885B2 (ja) | 標的にされた増大するｄｎａ脱メチル化 | |
| JP2016027807A5 (enExample) | ||
| Ioannidi et al. | Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases | |
| CN105063023B (zh) | 一种锌指核酸酶介导的猪mstn基因突变序列及其应用 | |
| Guo et al. | Multiplexed genome engineering for porcine fetal fibroblasts with gRNA–tRNA arrays based on CRISPR/Cas9 | |
| WO2026061506A1 (zh) | 核酸内切酶Gs12-7MAX及其介导的基因编辑系统 | |
| CN103421793B (zh) | 猪肝脏特异性表达基因ttr启动子的克隆及应用 | |
| WO2018164457A1 (ko) | C2cL 엔도뉴클레아제를 포함하는 유전체 교정용 조성물 및 이를 이용한 유전체 교정 방법 | |
| WO2022050377A1 (ja) | 標的ｄｎａの編集方法、標的ｄｎａが編集された細胞の製造方法、及びそれらに用いるｄｎａ編集システム | |
| CN103882043A (zh) | 羊驼TGF-β1-3′UTR双荧光素酶报告基因载体及其构建和应用 | |
| CN110004181B (zh) | 一种附加型CRISPR/Cas9表达载体及其构建方法与应用 | |
| CN112280800B (zh) | 一种构建体及其在制备动物衰老细胞示踪和衰老细胞清除药物中的应用 | |
| JP2018523999A (ja) | ヒト化心筋 | |
| Simonsson et al. | Changing cell fate by nuclear reprogramming | |
| JP7454881B2 (ja) | Ｃｒｉｓｐｒタイプｉ－ｄシステムを利用した標的ヌクレオチド配列改変技術 | |
| Ohtsuka | Development of Pronuclear Injection-Based Targeted Transgenesis in Mice Through Cre–loxP Site-Specific Recombination | |
| Tang et al. | In vitro CRISPR-Cas9-mediated efficient Ad5 vector modification | |
| WO2021171688A1 (ja) | 遺伝子ノックイン方法、遺伝子ノックイン細胞作製方法、遺伝子ノックイン細胞、がん化リスク評価方法、がん細胞製造方法、及びこれらに用いるためのキット | |
| CN102703506A (zh) | α1,2-岩藻糖转移酶基因沉默的体细胞克隆猪及其生产方法与应用 | |
| CN104099359B (zh) | 通过构建“大小染色体”高效敲除大肠杆菌基因组的方法 |