JP2009532053A5 - - Google Patents

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Publication number
JP2009532053A5
JP2009532053A5 JP2009503661A JP2009503661A JP2009532053A5 JP 2009532053 A5 JP2009532053 A5 JP 2009532053A5 JP 2009503661 A JP2009503661 A JP 2009503661A JP 2009503661 A JP2009503661 A JP 2009503661A JP 2009532053 A5 JP2009532053 A5 JP 2009532053A5
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JP
Japan
Prior art keywords
domain
sequence
cell
molecule
cytidine deaminase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009503661A
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English (en)
Japanese (ja)
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JP2009532053A (ja
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Publication date
Priority claimed from GBGB0607063.5A external-priority patent/GB0607063D0/en
Application filed filed Critical
Publication of JP2009532053A publication Critical patent/JP2009532053A/ja
Publication of JP2009532053A5 publication Critical patent/JP2009532053A5/ja
Pending legal-status Critical Current

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JP2009503661A 2006-04-07 2007-04-10 インヴィヴォでの核酸配列のエピジェネティック修飾用組成物および方法 Pending JP2009532053A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US79027306P 2006-04-07 2006-04-07
GBGB0607063.5A GB0607063D0 (en) 2006-04-07 2006-04-07 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
US79794206P 2006-05-05 2006-05-05
GBGB0623644.2A GB0623644D0 (en) 2006-04-07 2006-11-27 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
PCT/GB2007/001304 WO2007128982A2 (en) 2006-04-07 2007-04-10 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo

Publications (2)

Publication Number Publication Date
JP2009532053A JP2009532053A (ja) 2009-09-10
JP2009532053A5 true JP2009532053A5 (enExample) 2010-05-27

Family

ID=36539563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009503661A Pending JP2009532053A (ja) 2006-04-07 2007-04-10 インヴィヴォでの核酸配列のエピジェネティック修飾用組成物および方法

Country Status (5)

Country Link
US (2) US8298529B2 (enExample)
EP (1) EP2010660B1 (enExample)
JP (1) JP2009532053A (enExample)
GB (2) GB0607063D0 (enExample)
WO (1) WO2007128982A2 (enExample)

Families Citing this family (21)

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PL2274430T3 (pl) * 2008-04-30 2017-09-29 Sanbio Inc Komórki regenerujące nerwy ze zmianami w metylacji DNA
EP2128259A1 (en) * 2008-05-27 2009-12-02 Koninklijke Philips Electronics N.V. Therapy delivery and monitoring using a gene of interest-reporter fusion protein and optical imaging
US9683226B2 (en) * 2009-04-03 2017-06-20 Medical Research Council Mutants of activation-induced cytidine deaminase (AID) and methods of use
EP2258858A1 (en) * 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Transgenic LSD1 animal model for cancer
US20110104787A1 (en) * 2009-11-05 2011-05-05 President And Fellows Of Harvard College Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences
US20130011380A1 (en) * 2009-12-18 2013-01-10 Blau Helen M Use of Cytidine Deaminase-Related Agents to Promote Demethylation and Cell Reprogramming
CA2841710C (en) 2011-07-15 2021-03-16 The General Hospital Corporation Methods of transcription activator like effector assembly
US9890364B2 (en) * 2012-05-29 2018-02-13 The General Hospital Corporation TAL-Tet1 fusion proteins and methods of use thereof
EP3789405A1 (en) 2012-10-12 2021-03-10 The General Hospital Corporation Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
EP2954042B1 (en) 2013-02-07 2017-12-06 The General Hospital Corporation Tale transcriptional activators
US9721248B2 (en) 2014-03-04 2017-08-01 Bank Of America Corporation ATM token cash withdrawal
GB201418965D0 (enExample) 2014-10-24 2014-12-10 Ospedale San Raffaele And Fond Telethon
US10460367B2 (en) 2016-04-29 2019-10-29 Bank Of America Corporation System for user authentication based on linking a randomly generated number to the user and a physical item
US10268635B2 (en) 2016-06-17 2019-04-23 Bank Of America Corporation System for data rotation through tokenization
CA3045228C (en) * 2016-12-28 2024-01-02 Transgene Sa Oncolytic viruses and therapeutic molecules
AU2019255789B2 (en) 2018-04-19 2025-11-20 The Regents Of The University Of California Compositions and methods for gene editing
JP7541508B2 (ja) * 2018-08-23 2024-08-28 サンガモ セラピューティクス， インコーポレイテッド 操作された標的特異的な塩基エディター
JP7059965B2 (ja) * 2019-02-21 2022-04-26 株式会社豊田中央研究所 エピゲノム状態を制御する融合タンパク質及びその利用
US11680109B2 (en) 2019-05-29 2023-06-20 Duke University Compositions and methods for detection and measurement of RNA modifications through targeted RNA editing
CN113383749B (zh) * 2020-03-12 2025-11-18 中国医学科学院基础医学研究所 一种使用单个肿瘤细胞构建小鼠肿瘤模型的方法
JP7823919B2 (ja) * 2021-05-20 2026-03-04 国立大学法人群馬大学 エピゲノムが改変された動植物の親系統の製造に用いるための組成物およびその用途

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
FR2646438B1 (fr) 1989-03-20 2007-11-02 Pasteur Institut Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
CA2276306C (en) * 1996-12-30 2009-12-15 The Johns Hopkins University School Of Medicine Loss of imprinting-based in vitro diagnostic method to determine the propensity to develop cancer
US6534261B1 (en) * 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
AU3330700A (en) * 1999-03-29 2000-10-16 Tasuku Honjo Novel cytidine deaminase
AUPQ655100A0 (en) * 2000-03-29 2000-04-20 Am Asset Management Pty Ltd Device and method for cleaning golf balls
EP1276859B1 (en) * 2000-04-28 2007-02-07 Sangamo Biosciences Inc. Targeted modification of chromatin structure
IL154059A0 (en) 2000-07-21 2003-07-31 Syngenta Participations Ag Zinc finger domain recognition code and uses thereof
WO2002046412A2 (en) * 2000-12-07 2002-06-13 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
US8207142B2 (en) 2001-07-31 2012-06-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Inhibitor of DNA methylation
WO2003095636A2 (en) * 2002-05-10 2003-11-20 Medical Research Council Activation induced deaminase (aid)
GB0312676D0 (en) * 2003-06-02 2003-07-09 Babraham Inst Binding assay
FR2875239B1 (fr) * 2004-09-10 2007-07-20 Inst Necker Ass Loi De 1901 Procede pour l'acceleration des mutations somatiques et son application en proteomique

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