JP2009528345A5 - - Google Patents
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- Publication number
- JP2009528345A5 JP2009528345A5 JP2008557240A JP2008557240A JP2009528345A5 JP 2009528345 A5 JP2009528345 A5 JP 2009528345A5 JP 2008557240 A JP2008557240 A JP 2008557240A JP 2008557240 A JP2008557240 A JP 2008557240A JP 2009528345 A5 JP2009528345 A5 JP 2009528345A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- arylaliphatic
- pharmaceutical composition
- aliphatic
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77853206P | 2006-03-02 | 2006-03-02 | |
| US60/778,532 | 2006-03-02 | ||
| PCT/SG2006/000350 WO2007100304A1 (en) | 2006-03-02 | 2006-11-15 | Methods for cancer therapy and stem cell modulation |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013015684A Division JP2013121974A (ja) | 2006-03-02 | 2013-01-30 | 癌治療と幹細胞調節のための方法 |
| JP2013213366A Division JP5902138B2 (ja) | 2006-03-02 | 2013-10-11 | 癌治療と幹細胞調節のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009528345A JP2009528345A (ja) | 2009-08-06 |
| JP2009528345A5 true JP2009528345A5 (https=) | 2010-01-07 |
| JP5468782B2 JP5468782B2 (ja) | 2014-04-09 |
Family
ID=38459334
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008557240A Expired - Fee Related JP5468782B2 (ja) | 2006-03-02 | 2006-11-15 | 癌治療と幹細胞調節のための方法 |
| JP2013015684A Pending JP2013121974A (ja) | 2006-03-02 | 2013-01-30 | 癌治療と幹細胞調節のための方法 |
| JP2013213366A Expired - Fee Related JP5902138B2 (ja) | 2006-03-02 | 2013-10-11 | 癌治療と幹細胞調節のための方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013015684A Pending JP2013121974A (ja) | 2006-03-02 | 2013-01-30 | 癌治療と幹細胞調節のための方法 |
| JP2013213366A Expired - Fee Related JP5902138B2 (ja) | 2006-03-02 | 2013-10-11 | 癌治療と幹細胞調節のための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8058258B2 (https=) |
| EP (2) | EP1993553B1 (https=) |
| JP (3) | JP5468782B2 (https=) |
| AU (1) | AU2006339445A1 (https=) |
| SG (1) | SG170041A1 (https=) |
| TW (1) | TW200812590A (https=) |
| WO (1) | WO2007100304A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101909630A (zh) | 2007-11-02 | 2010-12-08 | 新加坡科技研究局 | 预防和治疗肿瘤的方法和化合物 |
| WO2010027935A1 (en) * | 2008-09-08 | 2010-03-11 | Merck Sharp & Dohme Corp. | Ahcy hydrolase inhibitors for treatment of hyper homocysteinemia |
| CN102369204A (zh) * | 2008-09-26 | 2012-03-07 | 新加坡科技研究局 | 3-脱氮瓶菌素衍生物 |
| WO2010111712A2 (en) * | 2009-03-27 | 2010-09-30 | Cold Spring Harbor Laboratory | Identification of rnai targets and use of rnai for rational therapy of chemotherapy-resistant leukemia and other cancers |
| US8491927B2 (en) | 2009-12-02 | 2013-07-23 | Nimble Epitech, Llc | Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor |
| SG180031A1 (en) * | 2010-10-15 | 2012-05-30 | Agency Science Tech & Res | Combination treatment of cancer |
| EP2646454B1 (en) | 2010-12-03 | 2015-07-08 | Epizyme, Inc. | 7-deazapurine modulators of histone methyltransferase, and methods of use thereof |
| CA2819620A1 (en) | 2010-12-03 | 2012-06-21 | Epizyme, Inc. | Modulators of histone methyltransferase, and methods of use thereof |
| US8580762B2 (en) | 2010-12-03 | 2013-11-12 | Epizyme, Inc. | Substituted purine and 7-deazapurine compounds |
| CA2831403A1 (en) * | 2011-05-19 | 2012-11-22 | Glax L.L.C. | Compositions and methods for treating and preventing cancer by targeting and inhibiting cancer stem cells |
| WO2013036846A2 (en) * | 2011-09-09 | 2013-03-14 | Koronis Pharmaceuticals, Incorporated | N4 derivatives of deoxycytidine prodrugs |
| US20150038548A1 (en) * | 2012-07-09 | 2015-02-05 | Metheor Therapeutics Corporation | Oligonucleotide inhibitors of dna methyltransferases and their use in treating diseases |
| US20150284422A1 (en) | 2012-08-10 | 2015-10-08 | Epizyme, Inc. | Inhibitors of protein methyltransferase dot1l and methods of use thereof |
| US9597348B2 (en) | 2012-09-06 | 2017-03-21 | Epizyme, Inc. | Method of treating leukemia |
| EP2908913B1 (en) | 2012-10-17 | 2018-10-03 | Cedars-Sinai Medical Center | Molecular signatures of ovarian cancer |
| US20160010059A1 (en) * | 2013-03-06 | 2016-01-14 | The Regents Of The University Of California | EXPANSION OF HEMATOPOIETIC PROGENITOR CELLS BY HISTONE METHYLTRANSFERASE G9a INHIBITION |
| US9738679B2 (en) | 2013-03-15 | 2017-08-22 | Epizyme, Inc. | Methods of synthesizing substituted purine compounds |
| WO2016022563A1 (en) | 2014-08-04 | 2016-02-11 | Auburn University | Enantiomers of the 1',6'-isomer of neplanocin a |
| WO2016149299A1 (en) * | 2015-03-16 | 2016-09-22 | Epinova Therapeutics Corp. | Therapeutic compounds that suppress protein arginine methyltransferase activity for reducing tumor cell proliferation |
| WO2020055663A1 (en) * | 2018-09-11 | 2020-03-19 | The Texas A&M University System | L-oligonucleotide inhibitors of polycomb repressive complex 2 (prc2) |
| WO2020057107A1 (zh) * | 2018-09-17 | 2020-03-26 | 诺未科技（北京）有限公司 | 一种组合物及其用途 |
| WO2023249714A1 (en) * | 2022-06-24 | 2023-12-28 | Memorial Sloan-Kettering Cancer Center | Therapeutic compositions and methods for activating double stranded rna response in cancer patients via dnmt1 targeted therapy |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US510260A (en) * | 1893-12-05 | Electric-arc-lighting system | ||
| US4975434A (en) * | 1986-05-27 | 1990-12-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Antiviral and anticancer cyclopentenyl cytosine |
| US4968690A (en) | 1986-05-27 | 1990-11-06 | United States Government As Represented By The Secretary Of The Dept. Of Health And Human Services | 3-deazaneplanocin, intermediates for it, and antiviral composition and method of treatment using it |
| JPH04327587A (ja) | 1991-04-26 | 1992-11-17 | Asahi Chem Ind Co Ltd | ６’−ｃ−アルキル−３−デアザネプラノシンａ誘導体、その製造法およびその用途 |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6090622A (en) | 1997-03-31 | 2000-07-18 | The Johns Hopkins School Of Medicine | Human embryonic pluripotent germ cells |
| JP2002507404A (ja) * | 1998-03-27 | 2002-03-12 | ジェネンテク・インコーポレイテッド | Ａｐｏ−２リガンド−抗ＨＥＲ−２抗体相乗作用 |
| SE517975C2 (sv) | 2000-05-30 | 2002-08-13 | Power Ab C | Fackverkskonstruktion av balkar sammansatta till ett tredimensionellt ramverk samt användning av en sådan fackverkskonstruktion |
| US20050191618A1 (en) | 2001-05-18 | 2005-09-01 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of human immunodeficiency virus (HIV) gene expression using short interfering nucleic acid (siNA) |
| ES2378524T3 (es) | 2002-09-13 | 2012-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Célula progenitora de megacariocitos de mamífero |
| AU2003295444A1 (en) | 2002-11-15 | 2004-06-15 | The Board Of Trustees Of The University Of Illinois | Methods for in vitro expansion of hematopoietic stem cells |
| US20050245559A1 (en) | 2004-01-23 | 2005-11-03 | Koul Hari K | Treatment and prevention of prostate cancer |
| WO2005105136A1 (en) | 2004-04-27 | 2005-11-10 | University Of South Florida | Nanogene therapy for cell proliferation disorders |
| ATE511859T1 (de) | 2004-07-20 | 2011-06-15 | Schering Corp | Apoptoseinduktion in toll-artige rezeptoren exprimierenden tumorzellen |
-
2006
- 2006-11-15 AU AU2006339445A patent/AU2006339445A1/en not_active Abandoned
- 2006-11-15 JP JP2008557240A patent/JP5468782B2/ja not_active Expired - Fee Related
- 2006-11-15 WO PCT/SG2006/000350 patent/WO2007100304A1/en not_active Ceased
- 2006-11-15 US US12/281,470 patent/US8058258B2/en not_active Expired - Fee Related
- 2006-11-15 EP EP06813130.9A patent/EP1993553B1/en not_active Not-in-force
- 2006-11-15 EP EP12175675.3A patent/EP2522352B1/en not_active Not-in-force
- 2006-11-15 SG SG201101385-1A patent/SG170041A1/en unknown
-
2007
- 2007-02-27 TW TW096106615A patent/TW200812590A/zh unknown
-
2011
- 2011-09-26 US US13/245,709 patent/US8211869B2/en not_active Expired - Fee Related
-
2013
- 2013-01-30 JP JP2013015684A patent/JP2013121974A/ja active Pending
- 2013-10-11 JP JP2013213366A patent/JP5902138B2/ja not_active Expired - Fee Related
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