JP2009525990A - 医薬組成物 - Google Patents

医薬組成物 Download PDF

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Publication number
JP2009525990A
JP2009525990A JP2008553588A JP2008553588A JP2009525990A JP 2009525990 A JP2009525990 A JP 2009525990A JP 2008553588 A JP2008553588 A JP 2008553588A JP 2008553588 A JP2008553588 A JP 2008553588A JP 2009525990 A JP2009525990 A JP 2009525990A
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JP
Japan
Prior art keywords
berberine
blood lipid
lipid lowering
functions
lowering agent
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Pending
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JP2008553588A
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English (en)
Japanese (ja)
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JP2009525990A5 (enExample
Inventor
ヤンウェン ワン，
ジェフ ジディコースキー，
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National Research Council Canada
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National Research Council Canada
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Publication of JP2009525990A publication Critical patent/JP2009525990A/ja
Publication of JP2009525990A5 publication Critical patent/JP2009525990A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14—Yeasts or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/104—Fermentation of farinaceous cereal or cereal material; Addition of enzymes or microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
JP2008553588A 2006-02-09 2007-02-09 医薬組成物 Pending JP2009525990A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71145506P 2006-02-09 2006-02-09
PCT/CA2007/000194 WO2007090289A1 (en) 2006-02-09 2007-02-09 Combinations of botanical extracts for promoting cardiovascular health

Publications (2)

Publication Number Publication Date
JP2009525990A true JP2009525990A (ja) 2009-07-16
JP2009525990A5 JP2009525990A5 (enExample) 2010-04-02

Family

ID=38344842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008553588A Pending JP2009525990A (ja) 2006-02-09 2007-02-09 医薬組成物

Country Status (6)

Country Link
US (1) US8895079B2 (enExample)
EP (1) EP1983989B1 (enExample)
JP (1) JP2009525990A (enExample)
CA (1) CA2640414C (enExample)
DK (1) DK1983989T3 (enExample)
WO (1) WO2007090289A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012524533A (ja) * 2009-04-23 2012-10-18 エス・アー・コルマン 薬剤として使用するための減コレステロール酪農製品
JP2022017496A (ja) * 2015-11-13 2022-01-25 シンセン ハイタイド バイオファーマシューティカル リミテッド 組成物、ならびにその適用および薬学的調製の方法
JP2023099689A (ja) * 2014-07-29 2023-07-13 シンセン ハイタイド バイオファーマシューティカル リミテッド ベルベリン塩、ウルソデオキシコール酸塩ならびに組み合わせ、その調製および適用方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003795B2 (en) 2007-06-22 2011-08-23 Cvi Pharmaceuticals Limited Compounds and compositions for reducing lipid levels
US8716249B2 (en) * 2008-01-31 2014-05-06 Energy Light Llc Compositions and methods for improving cardiovascular health
WO2009133458A1 (en) * 2008-05-01 2009-11-05 Afexa Life Sciences Inc. Pharmaceutical composition comprising extracts of huanglian and ku ding cha effective for lowering blood lipid levels
TWI454221B (en) * 2008-07-14 2014-10-01 Composition and method for inhibiting formation of body fat
ITMI20081403A1 (it) 2008-07-29 2010-01-30 Velleja Res Srl Composizioni comprendenti berberina e/o suoi analoghi o estratti che la contengano, per la prevenzione e il trattamento delle alterazioni del quadro lipidico e glucidico
IT1405432B1 (it) * 2010-12-16 2014-01-10 Funcional Food Res S R L Preparazione alimentare funzionale ed uso relativo.
WO2013016741A1 (en) * 2011-07-22 2013-01-31 Smith Conrad Anton Dietary supplement for use in a weight loss program
US20150335615A1 (en) * 2013-01-04 2015-11-26 Toshihisa Kawai Cholesterol-lowering compounds in combination with lipid metabolism-altering compounds of non-absorbable sugars, compounds that convert nh3 to nh4+, or hydrogen-generating compounds for the treatment of high cholesterol and inflammation
US9637731B2 (en) 2013-03-05 2017-05-02 Innovative Environmental Technologies, Inc. Heavy metal stabilization and methane inhibition during induced or naturally occurring reducing conditions in contaminated media
US9221699B2 (en) * 2013-03-05 2015-12-29 Innovative Environment Technologies, Inc. Inhibition of methane production during anaerobic reductive dechlorination
ITUB20150541A1 (it) 2015-03-03 2016-09-03 Acraf Composizione comprendente sostanze e/o estratti naturali
CA3023648C (en) * 2016-05-10 2023-11-28 Shenzhen Hightide Biopharmaceutical, Ltd. Pharmaceutical composition of berberine with epa and dha
MX2019011678A (es) * 2017-03-28 2020-02-12 IRP Health Pty Ltd Alcaloides de berberina en la prevencion y/o tratamiento de una enfermedad intestinal.
ES2645028B2 (es) * 2017-10-13 2018-06-04 Maria D. GÓMEZ GARRE Preparación farmacéutica única y estable que contiene berberina, en formulación de liberación lenta, una estatina y ubiquinol para el tratamiento de la enfermedad cardiovascular y los factores de riesgo asociados
IT202300006831A1 (it) 2023-04-06 2024-10-06 Dompe Farm Spa Composizione a base di estratti vegetali utile per il trattamento delle dislispidemie

Citations (8)

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US5589182A (en) * 1993-12-06 1996-12-31 Tashiro; Renki Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression
JPH0995452A (ja) * 1995-07-21 1997-04-08 Res Inst For Prod Dev 脂肪分解促進剤
JPH09255570A (ja) * 1996-03-21 1997-09-30 Fujitsuko Kk 血中脂質濃度を低減させる薬剤及び可食性組成物
JP2000264842A (ja) * 1999-03-18 2000-09-26 Medvill Co Ltd 知母と黄蘖の混合水性抽出物を包含する、抗炎症及び鎮痛用薬剤組成物並びにその製法
WO2001030359A1 (en) * 1999-10-29 2001-05-03 Triple Crown Ab Cholesterol lowering and blood lipids lowering composition
CN1437973A (zh) * 2003-01-23 2003-08-27 北京中医药大学 一种治疗缺血性脑中风的药物组合物及其制备方法
JP2004331635A (ja) * 2003-05-04 2004-11-25 Kaicho Se 細胞遣伝情報正常化材料及びその製法
JP2008513382A (ja) * 2004-09-17 2008-05-01 インスティチュート オブ メディシナル バイオテクノロジー、 チャイニーズ アカデミー オブ メディカル サイエンシズ 高脂血症を治療する方法及び組成物

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US20060078533A1 (en) 2004-10-12 2006-04-13 Omoigui Osemwota S Method of prevention and treatment of aging and age-related disorders including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimer's disease and cancer
US20060078532A1 (en) 2004-10-12 2006-04-13 Omoigui Osemwota S Method of prevention and treatment of Atherosclerosis, Peripheral vascular disease, Coronary artery disease, aging and age-related disorders including osteoporosis, arthritis, type 2 diabetes, dementia and Alzheimer's disease
US20060078531A1 (en) 2004-10-12 2006-04-13 Osemwota Sota Method of prevention and treatment of atherosclerosis, peripheral vascular disease, coronary artery disease, and age-related disorders including osteoporosis, arthritis, type 2 diabetes, dementia and Alzheimer's disease

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589182A (en) * 1993-12-06 1996-12-31 Tashiro; Renki Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression
JPH0995452A (ja) * 1995-07-21 1997-04-08 Res Inst For Prod Dev 脂肪分解促進剤
JPH09255570A (ja) * 1996-03-21 1997-09-30 Fujitsuko Kk 血中脂質濃度を低減させる薬剤及び可食性組成物
JP2000264842A (ja) * 1999-03-18 2000-09-26 Medvill Co Ltd 知母と黄蘖の混合水性抽出物を包含する、抗炎症及び鎮痛用薬剤組成物並びにその製法
WO2001030359A1 (en) * 1999-10-29 2001-05-03 Triple Crown Ab Cholesterol lowering and blood lipids lowering composition
CN1437973A (zh) * 2003-01-23 2003-08-27 北京中医药大学 一种治疗缺血性脑中风的药物组合物及其制备方法
JP2004331635A (ja) * 2003-05-04 2004-11-25 Kaicho Se 細胞遣伝情報正常化材料及びその製法
JP2008513382A (ja) * 2004-09-17 2008-05-01 インスティチュート オブ メディシナル バイオテクノロジー、 チャイニーズ アカデミー オブ メディカル サイエンシズ 高脂血症を治療する方法及び組成物

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JPN6012023680; Ａｍｅｒｉｃａｎ　Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　Ｎｕｔｒｉｔｉｏｎ Ｖｏｌ．６９, 1999, ｐ．２３１-２３６ *
JPN7012001704; Ｎａｔｕｒｅ　Ｍｅｄｉｃｉｎｅ Ｖｏｌ．１０，　Ｎｏ．１２, 2004, ｐ．１３４４-１３５１ *
JPN7012001705; Ｅｘｐｅｒｔ　Ｏｐｉｎｉｏｎ　Ｉｎｖｅｓｔｉｇａｔｉｏｎａｌ　Ｄｒｕｇｓ Ｖｏｌ．１４，　Ｎｏ．５, 2005, ｐ．６８３-６８５ *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012524533A (ja) * 2009-04-23 2012-10-18 エス・アー・コルマン 薬剤として使用するための減コレステロール酪農製品
JP2023099689A (ja) * 2014-07-29 2023-07-13 シンセン ハイタイド バイオファーマシューティカル リミテッド ベルベリン塩、ウルソデオキシコール酸塩ならびに組み合わせ、その調製および適用方法
JP2022017496A (ja) * 2015-11-13 2022-01-25 シンセン ハイタイド バイオファーマシューティカル リミテッド 組成物、ならびにその適用および薬学的調製の方法
JP7448511B2 (ja) 2015-11-13 2024-03-12 シンセン ハイタイド バイオファーマシューティカル リミテッド 組成物、ならびにその適用および薬学的調製の方法

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CA2640414C (en) 2013-07-09
WO2007090289A1 (en) 2007-08-16
US8895079B2 (en) 2014-11-25
EP1983989A1 (en) 2008-10-29
US20100239603A1 (en) 2010-09-23
EP1983989A4 (en) 2009-07-08
CA2640414A1 (en) 2007-08-16
DK1983989T3 (da) 2013-10-14
EP1983989B1 (en) 2013-07-03

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