JP2009525323A - 神経変性疾患の処置の為にｔｌｒ３アゴニストを使用する方法 - Google Patents

神経変性疾患の処置の為にｔｌｒ３アゴニストを使用する方法 Download PDF

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JP2009525323A
JP2009525323A JP2008553193A JP2008553193A JP2009525323A JP 2009525323 A JP2009525323 A JP 2009525323A JP 2008553193 A JP2008553193 A JP 2008553193A JP 2008553193 A JP2008553193 A JP 2008553193A JP 2009525323 A JP2009525323 A JP 2009525323A
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stathmin
tlr3
amino acid
cells
acid sequence
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JP2009525323A5 (enExample
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ノート，ヨハネス，マリア ファン
ブシブシ，マリカ
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ネーデルランドセ オルガニサティエ フォール トエゲパストナトールヴェテンシャッペリク オンデルゾエク ティエヌオー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Toxicology (AREA)
  • Psychology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008553193A 2006-02-03 2007-02-02 神経変性疾患の処置の為にｔｌｒ３アゴニストを使用する方法 Pending JP2009525323A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06075265A EP1815863A1 (en) 2006-02-03 2006-02-03 Use of TLR3 agonists for the treatment of neurodegenerative disorders
PCT/NL2007/050045 WO2007089151A1 (en) 2006-02-03 2007-02-02 Use of tlr3 agonists for the treatment of neurodegenerative disorders

Publications (2)

Publication Number Publication Date
JP2009525323A true JP2009525323A (ja) 2009-07-09
JP2009525323A5 JP2009525323A5 (enExample) 2010-03-25

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JP2008553193A Pending JP2009525323A (ja) 2006-02-03 2007-02-02 神経変性疾患の処置の為にｔｌｒ３アゴニストを使用する方法

Country Status (5)

Country Link
US (1) US20090253622A1 (enExample)
EP (2) EP1815863A1 (enExample)
JP (1) JP2009525323A (enExample)
AU (1) AU2007210379A1 (enExample)
WO (1) WO2007089151A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2015524402A (ja) * 2012-07-19 2015-08-24 ジム トレード コンサルティング ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー リージンク コマンディトゲゼルシャフト 創傷治療用の薬剤

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US20100130425A1 (en) * 2005-09-09 2010-05-27 Oregon Health & Science University Use of toll-like receptor ligands in treating excitotoxic injury, ischemia and/or hypoxia
US9003695B2 (en) 2006-12-29 2015-04-14 Genifuel Corporation Controlled growth environments for algae cultivation
GB201022049D0 (en) * 2010-12-29 2011-02-02 Imp Innovations Ltd Methods
US10421971B2 (en) 2014-01-15 2019-09-24 The University Of Chicago Anti-tumor therapy
US10105305B2 (en) * 2014-02-19 2018-10-23 The Johns Hopkins University Compositions and methods for promoting skin regeneration and hair growth
EP3298131B1 (en) 2015-05-20 2023-04-26 The Regents of The University of California Method for generating human dendritic cells for immunotherapy
MX2018005274A (es) 2015-10-30 2019-09-19 The Regents Of The Universtiy Of California Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.
EP3318270A1 (en) 2016-11-08 2018-05-09 RMB-Research GmbH Stathmin composition and method for treating wounds
CN110177887B (zh) 2016-11-10 2024-10-29 达丽斯生物医学公司 用于扩增和检测沙眼衣原体的多核苷酸
EP3551034A1 (en) 2016-12-07 2019-10-16 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
CA3046019A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a tlr modulator
US10450616B1 (en) 2018-05-09 2019-10-22 Talis Biomedical Corporation Polynucleotides for the amplification and detection of Chlamydia trachomatis
CN114173821A (zh) * 2019-01-14 2022-03-11 哈佛学院校长同事会 用于恢复stmn2水平的方法和组合物
WO2020232226A1 (en) 2019-05-16 2020-11-19 The Johns Hopkins University Compositions and methods for skin rejuvenation
JP7795914B2 (ja) * 2019-06-03 2026-01-08 クラリス コーポレーション 神経学的疾患を処置するためのオリゴヌクレオチドおよびその使用方法
WO2021076964A1 (en) * 2019-10-17 2021-04-22 Icahn School Of Medicine At Mount Sinai Stathmin 2 (stmn2) as a therapeutic target for parkinson's disease
US11891662B2 (en) * 2019-12-02 2024-02-06 Talis Biomedical Corporation Polynucleotides for amplification and detection of human beta actin
US20230107927A1 (en) 2020-02-28 2023-04-06 First Wave Bio, Inc. Methods of treating iatrogenic autoimmune colitis
US11047007B1 (en) 2020-03-23 2021-06-29 Talis Biomedical Corporation Polynucleotides for amplification and detection of SARS-CoV-2
US12616692B2 (en) 2020-07-02 2026-05-05 ViiV Healthcare Company; and Method of achieving HIV viral remission using long-acting antiretroviral agents
CN117320722A (zh) 2021-04-28 2023-12-29 埃尼奥制药公司 使用fxr激动剂作为联合治疗强烈增强tlr3激动剂的作用

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EP1288226A1 (en) * 2001-09-03 2003-03-05 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Modification of the expression levels of Toll-like receptor familiy members for influencing neurodegeneration and neuroprotection in the human central nervous system
WO2004078925A2 (en) * 2003-02-28 2004-09-16 Irm Llc Methods and compositions for treating and preventing neurodegenerative diseases
WO2005106038A2 (en) * 2004-04-15 2005-11-10 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders

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US20030044935A1 (en) * 1997-06-11 2003-03-06 Kenneth Jacobs Secreted proteins and polynucleotides encoding them
EP1242443A4 (en) * 1999-12-23 2005-06-22 Nuvelo Inc NEW NUCLEIC ACIDS AND POLYPEPTIDES
WO2002044424A1 (en) * 2000-12-01 2002-06-06 Board Of Trustees Of The University Of Arkansas Compositions, methods, apparatus and products comprising a stathmin/oncoprotein 18 sequence for detecting and treating cancer
JP2011516026A (ja) * 2002-11-26 2011-05-26 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための組成物と方法

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EP1288226A1 (en) * 2001-09-03 2003-03-05 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Modification of the expression levels of Toll-like receptor familiy members for influencing neurodegeneration and neuroprotection in the human central nervous system
WO2004078925A2 (en) * 2003-02-28 2004-09-16 Irm Llc Methods and compositions for treating and preventing neurodegenerative diseases
WO2005106038A2 (en) * 2004-04-15 2005-11-10 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders

Non-Patent Citations (5)

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JPN6012029351; Ｊｏｕｒｎａｌ　ｏｆ　Ｎｕｅｒｏｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．１５９, 2005, ｐ．１２-１９ *
JPN6012029353; Ｎｅｕｒｏｂｉｏｌｏｇｙ　ｏｆ　Ａｇｉｎｇ Ｖｏｌ．１７，　Ｎｏ．３, 1996, ｐ．３３１-３４１ *
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015524402A (ja) * 2012-07-19 2015-08-24 ジム トレード コンサルティング ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー リージンク コマンディトゲゼルシャフト 創傷治療用の薬剤

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EP1815863A1 (en) 2007-08-08
EP1991251A1 (en) 2008-11-19
WO2007089151A1 (en) 2007-08-09
US20090253622A1 (en) 2009-10-08
AU2007210379A1 (en) 2007-08-09

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