JP2009522281A - 翻訳機能障害に基づく治療法 - Google Patents

翻訳機能障害に基づく治療法 Download PDF

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Publication number
JP2009522281A
JP2009522281A JP2008548731A JP2008548731A JP2009522281A JP 2009522281 A JP2009522281 A JP 2009522281A JP 2008548731 A JP2008548731 A JP 2008548731A JP 2008548731 A JP2008548731 A JP 2008548731A JP 2009522281 A JP2009522281 A JP 2009522281A
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cell
cancer
compound
eif4e
group
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JP2009522281A5 (enExample
Inventor
ボーデン，キャサリン，エル．ビー．
ジェーミソン，ゴードン，エー．
カルコビッチ，ビルヤナ
ケントシス，アレックス
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Translational Therapeutics Inc
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Translational Therapeutics Inc
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Publication of JP2009522281A publication Critical patent/JP2009522281A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2008548731A 2005-12-28 2006-12-28 翻訳機能障害に基づく治療法 Pending JP2009522281A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US75446105P 2005-12-28 2005-12-28
US79404806P 2006-04-22 2006-04-22
US84858306P 2006-09-29 2006-09-29
US85440406P 2006-10-25 2006-10-25
PCT/US2006/049450 WO2007123579A2 (en) 2005-12-28 2006-12-28 Translational dysfunction based therapeutics

Related Child Applications (1)

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JP2015182943A Division JP2016040263A (ja) 2005-12-28 2015-09-16 翻訳機能障害に基づく治療法

Publications (2)

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JP2009522281A true JP2009522281A (ja) 2009-06-11
JP2009522281A5 JP2009522281A5 (enExample) 2013-04-11

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JP2008548731A Pending JP2009522281A (ja) 2005-12-28 2006-12-28 翻訳機能障害に基づく治療法
JP2015182943A Pending JP2016040263A (ja) 2005-12-28 2015-09-16 翻訳機能障害に基づく治療法

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EP (1) EP1971690B1 (enExample)
JP (2) JP2009522281A (enExample)
AU (1) AU2006342447B2 (enExample)
CA (1) CA2633715C (enExample)
NZ (1) NZ569883A (enExample)
WO (1) WO2007123579A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5602349B2 (ja) * 2007-11-20 2014-10-08 旭化成ファーマ株式会社 ミゾリビン及び／又はリバビリンの測定方法
WO2009118712A2 (en) * 2008-03-27 2009-10-01 Ecole Polytechnique Federale De Lausanne (Epfl) Novel dihydroxypyrrolidine derivatives as anti-cancer agents
US8599383B2 (en) 2009-05-06 2013-12-03 The Regents Of The University Of California Optical cytometry
WO2013019984A1 (en) * 2011-08-02 2013-02-07 The Regents Of The University Of California Rapid, massively parallel single-cell drug response measurements via live cell interferometry
CA2752008A1 (en) 2011-09-13 2013-03-13 Universite De Montreal Combination therapy using ribavirin as elf4e inhibitor
EP3004373B1 (en) 2013-05-24 2018-03-14 The Regents of The University of California Identifying desirable t lymphocytes by change in mass responses
WO2020214806A1 (en) * 2019-04-16 2020-10-22 The Regents Of The University Of California Protein translational control

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GB1010380A (en) * 1963-08-07 1965-11-17 Shionogi & Co Antibiotic showdomycin and a process for its production
JPH03503049A (ja) * 1988-01-07 1991-07-11 ユニバーシティ・オブ・リバプール 腺癌を治療するための逆転写酵素阻害剤
WO2004012769A1 (en) * 2002-08-02 2004-02-12 The Regents Of The University Of California Therapeutic inhibitionof protein kinases in cancer cells
JP2004509061A (ja) * 2000-02-15 2004-03-25 リバファーム・インコーポレイテッド カルボキサミジンで修飾した単環式塩基を有するヌクレオシドアナログ
WO2004100995A1 (en) * 2003-05-15 2004-11-25 Hemosol Lp Targeted delivery of anti-viral compounds through hemoglobin bioconjugation
US20050159372A1 (en) * 2000-02-15 2005-07-21 Robert Tam Nucleoside analogs with carboxamidine modified monocyclic base
JP2005524662A (ja) * 2002-02-28 2005-08-18 ビオタ インコーポレーティッド ヌクレオシド５’−一リン酸模倣物およびこれらのプロドラッグ

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US4419446A (en) 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
FI63596C (fi) 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US5023243A (en) 1981-10-23 1991-06-11 Molecular Biosystems, Inc. Oligonucleotide therapeutic agent and method of making same
FI71768C (fi) 1984-02-17 1987-02-09 Orion Yhtymae Oy Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
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US5177198A (en) 1989-11-30 1993-01-05 University Of N.C. At Chapel Hill Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates
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JPH0874B2 (ja) 1990-07-27 1996-01-10 アイシス・ファーマシューティカルス・インコーポレーテッド 遺伝子発現を検出および変調するヌクレアーゼ耐性、ピリミジン修飾オリゴヌクレオチド
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GB1010380A (en) * 1963-08-07 1965-11-17 Shionogi & Co Antibiotic showdomycin and a process for its production
JPH03503049A (ja) * 1988-01-07 1991-07-11 ユニバーシティ・オブ・リバプール 腺癌を治療するための逆転写酵素阻害剤
JP2004509061A (ja) * 2000-02-15 2004-03-25 リバファーム・インコーポレイテッド カルボキサミジンで修飾した単環式塩基を有するヌクレオシドアナログ
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EP1971690B1 (en) 2018-10-17
CA2633715A1 (en) 2007-11-01
EP1971690A4 (en) 2009-11-11
JP2016040263A (ja) 2016-03-24
AU2006342447A1 (en) 2007-11-01
WO2007123579A3 (en) 2008-02-28
NZ569883A (en) 2011-12-22
AU2006342447B2 (en) 2013-06-20
CA2633715C (en) 2016-06-14
WO2007123579A2 (en) 2007-11-01
WO2007123579B1 (en) 2008-04-24
EP1971690A2 (en) 2008-09-24

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